IgVH MUTATION DETECTION SCREENING Test
Test Name: IgVH MUTATION DETECTION SCREENING Test
Components: PCR, Sequencing
Price: 1760.0 AED
Sample Condition: 4 mL (2 mL min.) whole blood in 1 Lavender top (EDTA) tube. Ship refrigerated. DO NOT FREEZE.
Report Delivery: Sample Mon by 9 am; Report Fri
Test Type: Leukemia
Doctor: Hematologist, Oncologist
Test Department: MOLECULAR DIAGNOSTICS
Pre Test Information: No special preparation required
Test Details: The IgVH mutation detection screening test is a laboratory test used to detect mutations in the immunoglobulin variable region heavy chain (IgVH) gene. This gene is responsible for encoding the variable region of antibodies produced by B cells. Mutations in the IgVH gene can occur in various types of B cell malignancies, including chronic lymphocytic leukemia (CLL) and some non-Hodgkin lymphomas. These mutations can provide important prognostic information and help guide treatment decisions.
The IgVH mutation detection screening test typically involves sequencing the IgVH gene from a patient’s B cells and comparing it to a reference sequence. Any differences or mutations in the gene can be identified and analyzed. The presence or absence of mutations can provide information about the aggressiveness of the disease and the likelihood of response to certain treatments.
This test is often performed as part of the diagnostic workup for B cell malignancies and may be repeated over time to monitor disease progression or response to treatment. It is usually ordered by a hematologist or oncologist and requires a blood or bone marrow sample from the patient.
It is important to note that the IgVH mutation detection screening test is not a stand-alone diagnostic test, but rather a tool used in conjunction with other clinical and laboratory findings to assess the prognosis and guide treatment decisions for B cell malignancies.
Test Name | IgVH MUTATION DETECTION SCREENING Test |
---|---|
Components | |
Price | 1760.0 AED |
Sample Condition | 4 mL (2 mL min.) whole blood in 1 Lavender top (EDTA) tube. Ship refrigerated. DO NOT FREEZE. |
Report Delivery | Sample Mon by 9 am; Report Fri |
Method | PCR, Sequencing |
Test type | Leukemia |
Doctor | Hematologist, Oncologist |
Test Department: | MOLECULAR DIAGNOSTICS |
Pre Test Information | No special preparation required |
Test Details |
The IgVH mutation detection screening test is a laboratory test used to detect mutations in the immunoglobulin variable region heavy chain (IgVH) gene. This gene is responsible for encoding the variable region of antibodies produced by B cells. Mutations in the IgVH gene can occur in various types of B cell malignancies, including chronic lymphocytic leukemia (CLL) and some non-Hodgkin lymphomas. These mutations can provide important prognostic information and help guide treatment decisions. The IgVH mutation detection screening test typically involves sequencing the IgVH gene from a patient’s B cells and comparing it to a reference sequence. Any differences or mutations in the gene can be identified and analyzed. The presence or absence of mutations can provide information about the aggressiveness of the disease and the likelihood of response to certain treatments. This test is often performed as part of the diagnostic workup for B cell malignancies and may be repeated over time to monitor disease progression or response to treatment. It is usually ordered by a hematologist or oncologist and requires a blood or bone marrow sample from the patient. It is important to note that the IgVH mutation detection screening test is not a stand-alone diagnostic test, but rather a tool used in conjunction with other clinical and laboratory findings to assess the prognosis and guide treatment decisions for B cell malignancies. |