Test Price
2,800 AEDโ Home Collection Available
HPCA Gene DYT2 Genetic Test in UAE | 2,800 AED | DHA Certified
Executive Summary & Core Metrics
๐ฌ Guaranteed Precision
- 99.9% Diagnostic Sensitivity via ISO-Accredited NGS Full-Gene Sequencing.
- VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Daily 8 AM โ 11 PM).
- Clinical Guidance: Post-test teleconsultation for result interpretation.
- Insurance Support: Direct billing verification via WhatsApp +971 54 548 8731.
๐ Compliance & Peace of Mind
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL)
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields
- Federal Decree-Law No. 4 of 2016 on Medical Liability
- ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139)
Test Overview & Methodology
The HPCA Gene DYT2 Genetic Test is a high-precision next-generation sequencing (NGS) assay designed to detect pathogenic variants in the HPCA gene, causative for autosomal dominant dystonia type 2 (DYT2). This test is indispensable for neurologists and geneticists seeking definitive molecular diagnosis in patients with early-onset dystonia, especially when accompanied by a positive family history. The methodology covers the complete coding region and splice sites, detecting single nucleotide variants, insertions, deletions, and copy-number variants with >99.9% sensitivity.
| Feature | โญ Our Test (NGS Full HPCA Gene) | ๐ Sanger Sequencing (Alternative) |
|---|---|---|
| Precision / Coverage | Complete coding region & splice sites; detects SNVs, indels, CNVs | Limited to targeted amplicon; miss copy-number variants |
| Turnaround Time | 3โ4 weeks (ISO 15189-accredited lab) | 6โ8 weeks (often outsourced) |
| Diagnostic Yield | >99.9% sensitivity for pathogenic variants | ~90% for point mutations only |
| Clinical Reporting | Curated with ACMG classification & clinical correlation note | Basic variant report without contextual phenotype |
Physician Insight & Safety Protocols
โAs a Consultant Medical Genetics practicing under DHA (License: 9294403), I affirm that this genetic test is a powerful toolโbut it must be interpreted within the full clinical picture. A positive HPCA variant confirms hereditary dystonia, yet a negative result does not exclude other dystonia genes; always correlate with electromyography, brain MRI, and family history. Guide your patients gently through the implications, as this knowledge can alter treatment planning and family dynamics.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
โ ๏ธ Important Safety Advisory
Do not discontinue any prescribed medication (e.g., anticholinergics, botulinum toxin injections) without consulting your treating physician. Genetic results are supplementary and do not override clinical management.
๐ด Safety Exclusion Criteria & Emergency Red Flags
Exclusion Criteria (Do Not Proceed)
- Inability to provide informed consent or lack of legal guardian for minors.
- Recent blood transfusion (< 3 weeks) if submitting whole blood.
- Severe hemophilia or bleeding disorder without physician clearance.
- Known active infection with febrile illness (postpone collection).
Seek Immediate Medical Attention If:
- Sudden worsening of dystonia leading to airway compromise.
- Acute neck or trunk spasms causing difficulty breathing or swallowing.
- New onset of confusion, seizures, or suicidal ideation.
- Status dystonicus (prolonged, severe dystonic contractions).
Patient FAQ & Clinical Guidance
1. What is the HPCA gene DYT2 NGS test?
This advanced genetic test identifies mutations in the HPCA gene linked to hereditary dystonia type 2 (DYT2), providing a definitive molecular diagnosis to guide treatment and family genetic counseling.
2. How is the sample collected and what is the turnaround time?
A DHA-licensed phlebotomist collects a small blood sample at your home via our VIP Mobile Phlebotomy service. The final NGS report is securely delivered within 3 to 4 weeks.
3. Is this test covered by insurance in the UAE?
Insurance coverage varies by plan. Our team verifies direct billing eligibility and obtains preโapproval using neurological genetic testing codes before your appointment.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) for secure genetic data handling. All health data is processed in compliance with Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent follow Federal Decree-Law No. 4 of 2016 on Medical Liability. Our laboratory operates under DHA Facility License 1143 and is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | HPCA Gene DYT2 Genetic Test (NGS Full Gene Sequencing) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Whole Blood (Peripheral) |
| Methodology Used | Next-Generation Sequencing (NGS) โ Full Gene Coverage |
| ICD-10-CM Code | G24.2 |
| LOINC Code | 92558-8 |
| DHA Facility License & Address | License 1143 โ Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
ุฏุนู ุซูุงุฆู ุงููุบุฉ ู ุชุงุญ
ุงูุชุญูู ู ู ุงูุชุบุทูุฉ ุงูุชุฃู ูููุฉ
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
ุชููู ุนู ุงูุชุฎู ูู. ุฃุฑุณู ุตูุฑุฉ ู ู ุจุทุงูุฉ ุงูุชุฃู ูู ููุตูุฉ ุงูุทุจูุจ ุฅูู ูุฑูู ุงูุชุญูู ุงูู ุนุชู ุฏ ู ู ููุฆุฉ ุงูุตุญุฉ ุจุฏุจู ุนุจุฑ ุงููุงุชุณุงุจ. ุงุญุตู ุนูู ุชุญุฏูุซ ุงูุญุงูุฉ ูู ุฏูุงุฆู.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians