HLA PRE-TRANSPLANT WORKUP SENSITIZED RECIPIENT PANEL 3 Test
Test Name: HLA PRE-TRANSPLANT WORKUP SENSITIZED RECIPIENT PANEL 3 Test
Components: Donor: HLA DNA Typing for Kidney / Liver transplant, PCR Low resolution Luminex
Price: 4630.0 AED
Sample Condition: DONOR: 12 mL (10 mL min.) whole blood in 2 Yellow Top (ACD) tubes AND 4 mL (2 mL min.) whole blood in 1 Lavender top (EDTA) tube. Ship refrigerated. DO NOT FREEZE. Doctor’s prescription on the letter head with 1 photograph each of recipient and donor duly stamped AND Consent form for HLA Typing for Solid organ transplant (Form 33) is mandatory.
Report Delivery: 10-12 days
Method: Complement Dependent Cytotoxicity with DTT treatment, Reverse SSOP – Luminex, Luminex X-Map technology
Test type: Transplantation
Doctor: Nephrologist
Test Department:
Pre Test Information: Doctor’s prescription on the letter head with 1 photograph each of recipient and donor duly stamped AND Consent form for HLA Typing for Solid organ transplant (Form 33) is mandatory.
Test Details
The Sensitized Recipient Panel 3 (SRP3) test is a pre-transplant workup test used to determine the level of sensitization in a potential organ transplant recipient. Sensitization refers to the presence of antibodies in the recipient’s blood that may react against the transplanted organ.
The SRP3 test specifically measures the presence and strength of antibodies against a panel of specific human leukocyte antigens (HLAs). HLAs are proteins found on the surface of cells that play a critical role in the immune response. Matching the HLA types between the organ donor and recipient is important to minimize the risk of rejection.
The SRP3 test is typically performed using a technique called flow cytometry. This involves labeling the recipient’s blood cells with fluorescent markers that bind to specific HLA antigens. The labeled cells are then passed through a flow cytometer, which can detect and quantify the fluorescence emitted by the cells. This provides information about the presence and strength of antibodies against the HLA antigens.
The results of the SRP3 test help transplant teams assess the potential risk of antibody-mediated rejection in the recipient. If the recipient has a high level of antibodies against the donor’s HLA types, it may indicate a higher risk of rejection and the need for additional interventions, such as desensitization therapy or a different donor match.
Overall, the SRP3 test is an important tool in the pre-transplant workup process, helping transplant teams make informed decisions about organ transplantation and optimize outcomes for sensitized recipients.
| Test Name | HLA PRE-TRANSPLANT WORKUP SENSITIZED RECIPIENT PANEL 3 Test |
|---|---|
| Components | Donor: *HLA DNA Typing for Kidney / Liver transplant, PCR Low resolution Luminex |
| Price | 4630.0 AED |
| Sample Condition | DONOR: 12 mL (10 mL min.) whole blood in 2 Yellow Top (ACD) tubes AND 4 mL (2 mL min.) whole blood in 1 Lavender top (EDTA) tube. Ship refrigerated. DO NOT FREEZE.Doctor’s prescription on the letter head with 1 photograph each of recipient and donor duly stamped AND Consent form for HLA Typing for Solid organ transplant (Form 33) is mandatory. |
| Report Delivery | 10-12 days |
| Method | Complement Dependent Cytotoxicity with DTT treatment, Reverse SSOP – Luminex, Luminex X-Map technology |
| Test type | Transplantation |
| Doctor | Nephrologist |
| Test Department: | |
| Pre Test Information | Doctor’s prescription on the letter head with 1 photograph each of recipient and donor duly stamped AND Consent form for HLA Typing for Solid organ transplant (Form 33) is mandatory. |
| Test Details |
The Sensitized Recipient Panel 3 (SRP3) test is a pre-transplant workup test used to determine the level of sensitization in a potential organ transplant recipient. Sensitization refers to the presence of antibodies in the recipient’s blood that may react against the transplanted organ. The SRP3 test specifically measures the presence and strength of antibodies against a panel of specific human leukocyte antigens (HLAs). HLAs are proteins found on the surface of cells that play a critical role in the immune response. Matching the HLA types between the organ donor and recipient is important to minimize the risk of rejection. The SRP3 test is typically performed using a technique called flow cytometry. This involves labeling the recipient’s blood cells with fluorescent markers that bind to specific HLA antigens. The labeled cells are then passed through a flow cytometer, which can detect and quantify the fluorescence emitted by the cells. This provides information about the presence and strength of antibodies against the HLA antigens. The results of the SRP3 test help transplant teams assess the potential risk of antibody-mediated rejection in the recipient. If the recipient has a high level of antibodies against the donor’s HLA types, it may indicate a higher risk of rejection and the need for additional interventions, such as desensitization therapy or a different donor match. Overall, the SRP3 test is an important tool in the pre-transplant workup process, helping transplant teams make informed decisions about organ transplantation and optimize outcomes for sensitized recipients. |
