HLA PRE-TRANSPLANT WORKUP NON SENSITIZED RECIPIENT PANEL1 Test
At DNA Labs UAE, we offer the HLA pre-transplant workup for non-sensitized recipients, which includes the Non-Sensitized Recipient Panel 1 (NSRP1) test. This test is crucial in determining the compatibility between potential organ donors and recipients.
Test Details
The NSRP1 test involves analyzing the recipient’s blood or tissue sample to identify specific HLA antigens present on their cells. HLA antigens are proteins found on the surface of cells that play a vital role in the immune system’s recognition of self and non-self cells.
By determining the recipient’s HLA typing, our healthcare providers can identify potential organ donors whose HLA antigens closely match the recipient’s. A closer match between the donor and recipient’s HLA antigens reduces the risk of organ rejection and significantly improves the chances of a successful transplant.
The NSRP1 test is performed using molecular techniques such as polymerase chain reaction (PCR) or sequence-specific oligonucleotide probe (SSOP) analysis. These techniques allow for accurate and detailed identification of HLA antigens.
Other Tests in the Pre-Transplant Workup
In addition to the NSRP1 test, we may also perform other tests as part of the pre-transplant workup for non-sensitized recipients:
- Crossmatching tests: These tests assess the compatibility between the recipient and potential donors.
- Antibody screening: This test detects any pre-existing antibodies that may increase the risk of rejection.
- Additional HLA typing tests: If necessary, we may perform additional HLA typing tests to gather more detailed information.
Test Cost and Sample Requirements
The HLA PRE-TRANSPLANT WORKUP NON SENSITIZED RECIPIENT PANEL1 test costs AED 3280.0. The sample requirements for the test are as follows:
- Donor: 12 mL (10 mL min.) whole blood in 2 Yellow Top (ACD) tubes and 4 mL (2 mL min.) whole blood in 1 Lavender top (EDTA) tube.
- Ship the samples refrigerated. Do not freeze.
- Doctor’s prescription on the letterhead with 1 photograph each of the recipient and donor duly stamped.
- Consent form for HLA Typing for Solid organ transplant (Form 33) is mandatory.
Report Delivery
The report for the HLA PRE-TRANSPLANT WORKUP NON SENSITIZED RECIPIENT PANEL1 test will be delivered within 10-12 days.
Conclusion
The HLA pre-transplant workup, including the NSRP1 test, is essential in determining the best possible organ match for non-sensitized recipients. By identifying compatible organ donors, we can significantly increase the chances of a successful transplant outcome. At DNA Labs UAE, we are dedicated to providing accurate and detailed HLA typing services to support successful organ transplants.
Test Name | HLA PRE-TRANSPLANT WORKUP NON SENSITIZED RECIPIENT PANEL1 Test |
---|---|
Components | Donor: *HLA DNA Typing for Kidney / Liver transplant, PCR Low resolution Luminex |
Price | 3280.0 AED |
Sample Condition | DONOR: 12 mL (10 mL min.) whole blood in 2 Yellow Top (ACD) tubes AND 4 mL (2 mL min.) whole blood in 1 Lavender top (EDTA) tube. Ship refrigerated. DO NOT FREEZE. Doctor’s prescription on the letter head with 1 photograph each of recipient and donor duly stamped ANDConsent form for HLA Typing for Solid organ transplant (Form 33) is mandatory. |
Report Delivery | 10-12 days |
Method | Complement Dependent Cytotoxicity with DTT treatment, Reverse SSOP – Luminex, Luminex X-Map technology |
Test type | Transplantation |
Doctor | Nephrologist |
Test Department: | |
Pre Test Information | Doctor’s prescription on the letter head with 1 photograph each of recipient and donor duly stamped ANDConsent form for HLA Typing for Solid organ transplant (Form 33) is mandatory. |
Test Details | The HLA pre-transplant workup for a non-sensitized recipient typically involves several tests, including the Non-Sensitized Recipient Panel 1 (NSRP1) test. This test is performed to determine the recipient’s HLA typing and assess their compatibility with potential organ donors. The NSRP1 test involves analyzing the recipient’s blood or tissue sample to identify specific HLA antigens present on their cells. HLA antigens are proteins found on the surface of cells that play a crucial role in the immune system’s recognition of self and non-self cells. By determining the recipient’s HLA typing, healthcare providers can identify potential organ donors whose HLA antigens closely match the recipient’s. A closer match between the donor and recipient’s HLA antigens reduces the risk of organ rejection and improves the chances of a successful transplant. The NSRP1 test is usually performed using molecular techniques, such as polymerase chain reaction (PCR) or sequence-specific oligonucleotide probe (SSOP) analysis. These techniques allow for accurate and detailed identification of HLA antigens. In addition to the NSRP1 test, other tests may be performed as part of the pre-transplant workup for a non-sensitized recipient. These may include crossmatching tests to assess compatibility between the recipient and potential donors, antibody screening to detect any pre-existing antibodies that may increase the risk of rejection, and additional HLA typing tests if necessary. Overall, the HLA pre-transplant workup, including the NSRP1 test, is essential in determining the best possible organ match for a non-sensitized recipient and ensuring a successful transplant outcome. |