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HLA Mixed Antibody Screen – PRA Class I II and MICA Test Cost

Original price was: 2,080 د.إ.Current price is: 1,870 د.إ.

-10%

The HLA Mixed Antibody Screen – PRA (Panel Reactive Antibody) Class I, II, and MICA Test is a sophisticated diagnostic assessment designed to evaluate the presence of antibodies against human leukocyte antigens (HLA) and Major Histocompatibility Complex class I chain-related gene A (MICA) in the bloodstream. This test is crucial for individuals undergoing or planning to undergo organ transplantation, as the presence of these antibodies can significantly affect the compatibility between donor and recipient, potentially leading to transplant rejection.

The test specifically screens for antibodies against HLA Class I and Class II antigens, which are critical for immune response and organ transplant compatibility. Additionally, it assesses antibodies against MICA, which have been associated with transplant rejection and reduced graft survival. By identifying these antibodies, healthcare providers can better match donors and recipients, minimize the risk of rejection, and improve transplant outcomes.

Performed at DNA Labs UAE, a leading diagnostic and research facility, the test is executed with precision and accuracy, ensuring reliable results for patients and healthcare professionals. The cost of the HLA Mixed Antibody Screen – PRA Class I, II, and MICA Test is 1870 AED, reflecting the comprehensive and detailed analysis involved in this assessment.

This test represents a critical step in pre-transplant evaluation, helping to ensure the highest levels of compatibility and success in organ transplantation procedures.

Description

HLA Mixed Antibody Screen – PRA Class I II and MICA Test

Test Name: HLA MIXED ANTIBODY SCREEN – PRA CLASS I II and MICA Test

Components:

PRA Class I
PRA Class II
Anti MICA antibodies

Price: 1870.0 AED

Sample Condition: 3 mL (1.5 mL min.) serum from 1 SST. Only Recipient sample required. Ship refrigerated or frozen. Provide brief clinical history.

Report Delivery: 10-12 days

Method: Luminex X-Map technology

Test type: Transplantation

Doctor: Nephrologist, Gastroenterologist, Surgeon

Test Department:

Pre Test Information: Only Recipient sample required. Provide brief clinical history.

Test Details:

The HLA Mixed Antibody Screen – PRA Class I II & MICA Test is a laboratory test used to determine the presence of antibodies against human leukocyte antigens (HLA) in a patient’s blood. HLA antigens are proteins found on the surface of cells that play a crucial role in the body’s immune response.

The test specifically looks for the presence of antibodies against Class I and Class II HLA antigens, as well as MICA antigens. Class I HLA antigens are found on nearly all nucleated cells in the body, while Class II HLA antigens are primarily found on immune cells such as B cells, T cells, and antigen-presenting cells.

The presence of antibodies against HLA antigens can be problematic in certain medical situations, such as organ transplantation. If a patient has pre-existing antibodies against the HLA antigens of a potential organ donor, it can lead to rejection of the transplanted organ. Therefore, this test is often performed prior to transplantation to assess the patient’s risk of developing antibody-mediated rejection.

The HLA Mixed Antibody Screen – PRA Class I II & MICA Test involves mixing the patient’s serum (the liquid portion of the blood) with a panel of cells that express different HLA antigens. If antibodies are present in the patient’s serum, they will bind to the HLA antigens on the cells, forming visible clumps or agglutination. The degree of agglutination is then assessed and reported as a percentage of panel-reactive antibodies (PRA). A higher PRA percentage indicates a higher risk of antibody-mediated rejection.

In addition to Class I and Class II HLA antigens, the test also includes MICA antigens. MICA antigens are a type of non-classical HLA antigen that can also elicit an immune response. Including MICA antigens in the test helps to provide a more comprehensive assessment of the patient’s antibody profile.

Overall, the HLA Mixed Antibody Screen – PRA Class I II & MICA Test is an important tool in assessing the risk of antibody-mediated rejection in organ transplantation and other medical situations where HLA antibodies may be relevant.

Test Name	HLA MIXED ANTIBODY SCREEN – PRA CLASS I II and MICA Test
Components	PRA Class IPRA Class II*Anti MICA antibodies
Price	1870.0 AED
Sample Condition	3 mL (1.5 mL min.) serum from 1 SST. Only Recipient sample required. Ship refrigerated or frozen. Provide brief clinical history.
Report Delivery	10-12 days
Method	Luminex X-Map technology
Test type	Transplantation
Doctor	Nephrologist, Gastroenterologist, Surgeon
Test Department:
Pre Test Information	Only Recipient sample required. Provide brief clinical history.
Test Details	The HLA Mixed Antibody Screen – PRA Class I II & MICA Test is a laboratory test used to determine the presence of antibodies against human leukocyte antigens (HLA) in a patient’s blood. HLA antigens are proteins found on the surface of cells that play a crucial role in the body’s immune response. The test specifically looks for the presence of antibodies against Class I and Class II HLA antigens, as well as MICA antigens. Class I HLA antigens are found on nearly all nucleated cells in the body, while Class II HLA antigens are primarily found on immune cells such as B cells, T cells, and antigen-presenting cells. The presence of antibodies against HLA antigens can be problematic in certain medical situations, such as organ transplantation. If a patient has pre-existing antibodies against the HLA antigens of a potential organ donor, it can lead to rejection of the transplanted organ. Therefore, this test is often performed prior to transplantation to assess the patient’s risk of developing antibody-mediated rejection. The HLA Mixed Antibody Screen – PRA Class I II & MICA Test involves mixing the patient’s serum (the liquid portion of the blood) with a panel of cells that express different HLA antigens. If antibodies are present in the patient’s serum, they will bind to the HLA antigens on the cells, forming visible clumps or agglutination. The degree of agglutination is then assessed and reported as a percentage of panel-reactive antibodies (PRA). A higher PRA percentage indicates a higher risk of antibody-mediated rejection. In addition to Class I and Class II HLA antigens, the test also includes MICA antigens. MICA antigens are a type of non-classical HLA antigen that can also elicit an immune response. Including MICA antigens in the test helps to provide a more comprehensive assessment of the patient’s antibody profile. Overall, the HLA Mixed Antibody Screen – PRA Class I II & MICA Test is an important tool in assessing the risk of antibody-mediated rejection in organ transplantation and other medical situations where HLA antibodies may be relevant.