Sale!

HLA Hypersensitivity to Allopurinol B*5801 Test Cost

Original price was: 1,560 د.إ.Current price is: 1,400 د.إ.

-10%

The HLA Hypersensitivity to Allopurinol B*5801 Test is a specialized diagnostic assessment designed to identify individuals at increased risk of developing severe adverse reactions to allopurinol, a medication commonly used to treat gout and certain types of kidney stones. This test is particularly crucial as it screens for the presence of the HLA-B*5801 allele, a genetic variant associated with a heightened sensitivity to allopurinol, leading to potentially life-threatening conditions such as Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN).

Conducted at DNA Labs UAE, a leading facility in genetic and molecular diagnostics, the test ensures precision and reliability in results. The process involves collecting a DNA sample, typically through a blood draw or cheek swab, which is then analyzed for the specific HLA-B*5801 allele. The presence of this allele can significantly influence the course of treatment for individuals requiring allopurinol, guiding healthcare providers to consider alternative medications or adjust dosages accordingly to mitigate the risk of severe reactions.

The cost of the HLA Hypersensitivity to Allopurinol B*5801 Test at DNA Labs UAE is 1400 AED, an investment in personalized medicine that can greatly enhance patient safety and treatment efficacy. By identifying genetic predispositions to drug hypersensitivity, this test represents a critical step forward in the field of pharmacogenomics, offering a tailored approach to medication management and reducing the likelihood of adverse drug reactions.

Description

HLA Hypersensitivity to Allopurinol B*5801 Test

Test Name: HLA Hypersensitivity to Allopurinol B*5801 Test

Components: PCR, Sequencing

Price: 1400.0 AED

Sample Condition: 4 mL (3 mL min.) whole blood in 1 Lavender Top (EDTA) tube OR 6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube OR Buccal swab collected in a sterile container. Ship refrigerated. DO NOT FREEZE.

Report Delivery: 10-12 days

Test Type: Disorders of Kidney

Doctor: Nephrologist

Test Department: Pre Test Information

No special preparation required

Test Details:

HLA hypersensitivity to allopurinol, specifically the HLA-B*58:01 allele, can be tested using genetic testing methods. This test is used to determine if an individual is at risk of developing a severe allergic reaction called Stevens-Johnson syndrome or toxic epidermal necrolysis when taking allopurinol.

The test involves analyzing a sample of the patient’s DNA, usually obtained through a blood sample or cheek swab. The DNA is then tested for the presence of the HLA-B*58:01 allele. If the HLA-B*58:01 allele is detected, it indicates an increased risk of developing a severe allergic reaction to allopurinol.

In such cases, alternative medications may be considered to manage conditions like gout, for which allopurinol is commonly prescribed.

It is important to note that this test is primarily used as a screening tool to identify individuals at higher risk. It does not guarantee that a severe reaction will occur or rule out the possibility of a reaction in those who do not have the allele. Clinical judgment and further evaluation are still necessary to make treatment decisions.

Test Name	HLA HYPERSENSITIVITY TO ALLOPURINOL B*5801 Test
Components
Price	1400.0 AED
Sample Condition	4 mL (3 mL min.) whole blood in 1 Lavender Top (EDTA) tube OR6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube OR Buccal swab collected in a sterile container. Ship refrigerated. DO NOT FREEZE.
Report Delivery	10-12 days
Method	PCR, Sequencing
Test type	Disorders of Kidney
Doctor	Nephrologist
Test Department:
Pre Test Information	No special preparation required
Test Details	HLA hypersensitivity to allopurinol, specifically the HLA-B58:01 allele, can be tested using genetic testing methods. This test is used to determine if an individual is at risk of developing a severe allergic reaction called Stevens-Johnson syndrome or toxic epidermal necrolysis when taking allopurinol. The test involves analyzing a sample of the patient’s DNA, usually obtained through a blood sample or cheek swab. The DNA is then tested for the presence of the HLA-B58:01 allele. If the HLA-B*58:01 allele is detected, it indicates an increased risk of developing a severe allergic reaction to allopurinol. In such cases, alternative medications may be considered to manage conditions like gout, for which allopurinol is commonly prescribed. It is important to note that this test is primarily used as a screening tool to identify individuals at higher risk. It does not guarantee that a severe reaction will occur or rule out the possibility of a reaction in those who do not have the allele. Clinical judgment and further evaluation are still necessary to make treatment decisions.