HLA – CELIAC DISEASE DR-DQB1-DQA1 HAPLOTYPE ASSOCIATION INCLUDING DQ2DQ8 Test
Welcome to DNA Labs UAE’s blog on the HLA – CELIAC DISEASE DR-DQB1-DQA1 HAPLOTYPE ASSOCIATION INCLUDING DQ2DQ8 test. In this blog, we will provide detailed information about the test, its components, cost, symptoms, diagnosis, and more.
Test Details
The HLA – CELIAC DISEASE (DR-DQB1-DQA1 HAPLOTYPE ASSOCIATION INCLUDING DQ2DQ8) test is a genetic test used to determine the risk of developing celiac disease. Celiac disease is an autoimmune disorder that affects the small intestine and is triggered by the consumption of gluten.
The test analyzes specific genes, namely HLA-DR, HLA-DQB1, and HLA-DQA1, to identify certain genetic variations or haplotypes that are associated with an increased risk of developing celiac disease. The most common genetic variants associated with celiac disease are HLA-DQ2 and HLA-DQ8.
The presence of HLA-DQ2 and/or HLA-DQ8 haplotypes increases the risk of developing celiac disease, although not everyone with these haplotypes will develop the condition. Conversely, the absence of these haplotypes does not exclude the possibility of developing celiac disease.
This test is typically performed on individuals who have symptoms suggestive of celiac disease or have a family history of the condition. It can help in confirming the diagnosis of celiac disease and guiding further management, such as adhering to a gluten-free diet.
It is important to note that this test alone is not sufficient to diagnose celiac disease definitively. A confirmed diagnosis usually requires additional tests, such as blood tests for specific antibodies and a small intestinal biopsy.
Test Components and Price
The HLA – CELIAC DISEASE DR-DQB1-DQA1 HAPLOTYPE ASSOCIATION INCLUDING DQ2DQ8 test costs AED 1330.0.
The required sample condition for the test is 4 mL (3 mL min.) whole blood in 1 Lavender Top (EDTA) tube OR 6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube. The sample should be shipped refrigerated and should not be frozen.
Report Delivery
The report for the HLA – CELIAC DISEASE DR-DQB1-DQA1 HAPLOTYPE ASSOCIATION INCLUDING DQ2DQ8 test is typically delivered within 10-12 days.
Method and Test Type
The method used for this test is SSP – PCR (Sequence-Specific Primer Polymerase Chain Reaction).
The test type is Malabsorption Syndrome, which is a condition characterized by the body’s inability to absorb certain nutrients properly.
Doctor and Test Department
The test is typically ordered by a Gastroenterologist, a specialist in the digestive system and its disorders.
The test is conducted in the Test Department of DNA Labs UAE.
Pre Test Information
No special preparation is required before undergoing the HLA – CELIAC DISEASE DR-DQB1-DQA1 HAPLOTYPE ASSOCIATION INCLUDING DQ2DQ8 test.
It is recommended to consult with your healthcare provider for any specific instructions.
Thank you for reading our blog on the HLA – CELIAC DISEASE DR-DQB1-DQA1 HAPLOTYPE ASSOCIATION INCLUDING DQ2DQ8 test. For more information or to schedule a test, please contact DNA Labs UAE.
| Test Name | HLA – CELIAC DISEASE DR-DQB1-DQA1 HAPLOTYPE ASSOCIATION INCLUDING DQ2DQ8 Test |
|---|---|
| Components | |
| Price | 1330.0 AED |
| Sample Condition | 4 mL (3 mL min.) whole blood in 1 Lavender Top (EDTA) tube OR6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube. Ship refrigerated. DO NOT FREEZE. |
| Report Delivery | 10-12 days |
| Method | SSP – PCR |
| Test type | Malabsorption Syndrome |
| Doctor | Gastroenterologist |
| Test Department: | |
| Pre Test Information | No special preparation required |
| Test Details | HLA – CELIAC DISEASE (DR-DQB1-DQA1 HAPLOTYPE ASSOCIATION INCLUDING DQ2DQ8) test is a genetic test used to determine the risk of developing celiac disease. Celiac disease is an autoimmune disorder that affects the small intestine and is triggered by the consumption of gluten. The test analyzes specific genes, namely HLA-DR, HLA-DQB1, and HLA-DQA1, to identify certain genetic variations or haplotypes that are associated with an increased risk of developing celiac disease. The most common genetic variants associated with celiac disease are HLA-DQ2 and HLA-DQ8. The presence of HLA-DQ2 and/or HLA-DQ8 haplotypes increases the risk of developing celiac disease, although not everyone with these haplotypes will develop the condition. Conversely, the absence of these haplotypes does not exclude the possibility of developing celiac disease. This test is typically performed on individuals who have symptoms suggestive of celiac disease or have a family history of the condition. It can help in confirming the diagnosis of celiac disease and guiding further management, such as adhering to a gluten-free diet. It is important to note that this test alone is not sufficient to diagnose celiac disease definitively. A confirmed diagnosis usually requires additional tests, such as blood tests for specific antibodies and a small intestinal biopsy. |
