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HLA-B*5701 Genotyping for Abacavir Hypersensitivity Test

600 د.إ

-25%

HLA-B*5701 Genotyping for Abacavir Hypersensitivity Test is a specialized genetic test performed to identify individuals at risk of experiencing a hypersensitivity reaction to abacavir, a medication used in the treatment of HIV. This test is crucial because a hypersensitivity reaction can be severe and potentially life-threatening, but it is largely preventable if those at risk are identified before starting the medication. The test focuses on detecting the presence of the HLA-B*5701 allele, a genetic variant strongly associated with an increased risk of developing abacavir hypersensitivity.

At DNA Labs UAE, the test is available for 600 AED, offering a valuable tool for healthcare providers in personalizing HIV treatment plans. By identifying patients who carry the HLA-B*5701 allele, clinicians can make informed decisions to avoid prescribing abacavir to these individuals, thereby significantly reducing the risk of adverse reactions. This genotyping test represents an important step in the movement towards personalized medicine, ensuring that treatments are both safe and effective for individual patients.

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HLA-B*5701 Genotyping for Abacavir Hypersensitivity Test

At DNA Labs UAE, we offer the HLA-B*5701 Genotyping test for Abacavir Hypersensitivity. This test is used to determine an individual’s HLA-B*5701 genotype and assess their risk of developing hypersensitivity reactions to the antiretroviral drug Abacavir.

Test Details

The HLA-B*5701 genotyping test is specifically performed to identify individuals who have a significantly increased risk of developing severe hypersensitivity reactions to Abacavir. Abacavir is commonly used in the treatment of HIV infection, but approximately 5-8% of individuals with European ancestry and a smaller percentage of individuals from other populations carry the HLA-B*5701 allele.

Hypersensitivity reactions to Abacavir can manifest as a variety of symptoms, including fever, rash, gastrointestinal symptoms, respiratory symptoms, and in severe cases, life-threatening reactions such as Stevens-Johnson syndrome or toxic epidermal necrolysis.

It is important to note that HLA-B*5701 genotyping is specific to the risk of hypersensitivity reactions to Abacavir and does not provide information about other drug allergies or adverse reactions. Additionally, this test is only relevant for individuals who may be prescribed Abacavir as part of their HIV treatment.

Test Components

  • EDTA Vacutainer (2ml)

Test Price

The cost of the HLA-B*5701 Genotyping for Abacavir Hypersensitivity Test is 600.0 AED.

Sample Condition

The test requires a peripheral blood sample.

Report Delivery

Reports are typically delivered within 1 week.

Method

The HLA-B*5701 genotyping test is performed using Sanger Sequencing.

Test Type

This test falls under the category of Genetics.

Referring Doctor

This test can be ordered by a Gynecologist.

Test Department

This test is conducted in the Genetics department.

Pre Test Information

HLA-B*57:01 Genotyping (for Abacavir Hypersensitivity) can be done with a doctor’s prescription. However, please note that the prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.

Test Name HLA-B*5701 Genotyping for Abacavir Hypersensitivity Test
Components EDTA Vacutainer (2ml)
Price 600.0 AED
Sample Condition Peripheral blood
Report Delivery 1 week
Method Sanger Sequencing
Test type Genetics
Doctor Gynecologist
Test Department:
Pre Test Information HLA-B*57:01 Genotyping (for Abacavir Hypersensitivity) can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.
Test Details

HLA-B*57:01 genotyping is a genetic test used to determine an individual’s HLA-B*57:01 genotype. This test is specifically performed to assess the risk of developing hypersensitivity reactions to the antiretroviral drug Abacavir.

Abacavir is commonly used in the treatment of HIV infection. However, approximately 5-8% of individuals with European ancestry and a smaller percentage of individuals from other populations carry the HLA-B*57:01 allele. These individuals have a significantly increased risk of developing a severe hypersensitivity reaction to Abacavir.

The hypersensitivity reaction can manifest as a variety of symptoms, including fever, rash, gastrointestinal symptoms, respiratory symptoms, and in severe cases, life-threatening reactions such as Stevens-Johnson syndrome or toxic epidermal necrolysis.

HLA-B*57:01 genotyping is typically performed prior to initiating Abacavir therapy to identify individuals at risk for hypersensitivity reactions. If an individual tests positive for HLA-B*57:01, Abacavir should be avoided, and alternative antiretroviral medications should be considered.

Genotyping for HLA-B*57:01 can be done using various methods, including polymerase chain reaction (PCR) and sequence-specific oligonucleotide probes (SSOP). These techniques detect specific genetic variations associated with the HLA-B*57:01 allele.

It is important to note that HLA-B*57:01 genotyping is specific to the risk of hypersensitivity reactions to Abacavir and does not provide information about other drug allergies or adverse reactions. Additionally, this test is only relevant for individuals who may be prescribed Abacavir as part of their HIV treatment.