HEXA Gene Tay-Sachs disease Genetic Test
At DNA Labs UAE, we offer the HEXA Gene Tay-Sachs disease Genetic Test at a cost of AED 3200.0.
Test Details
The HEXA Gene Tay-Sachs disease NGS Genetic Test is a genetic test that utilizes Next-Generation Sequencing (NGS) technology to analyze the HEXA gene for mutations associated with Tay-Sachs disease. Tay-Sachs disease is a rare genetic disorder characterized by the progressive destruction of nerve cells in the brain and spinal cord.
The HEXA gene provides instructions for producing an enzyme called beta-hexosaminidase A, which is responsible for breaking down a fatty substance called GM2 ganglioside. Mutations in the HEXA gene can lead to a deficiency or complete absence of this enzyme, resulting in the accumulation of GM2 ganglioside in the nerve cells and causing the symptoms of Tay-Sachs disease.
The HEXA Gene Tay-Sachs disease NGS Genetic Test involves obtaining a DNA sample, typically through a blood or saliva sample, and analyzing it using NGS technology. NGS allows for the simultaneous sequencing of multiple genes, including the HEXA gene, to identify any genetic variants or mutations.
By detecting mutations in the HEXA gene, this test can determine if an individual carries a mutation associated with Tay-Sachs disease. Carriers of a single mutation are typically unaffected by the disease but can pass the mutation on to their children. If both parents are carriers, there is a 25% chance with each pregnancy that their child will inherit two copies of the mutated gene and develop Tay-Sachs disease.
This genetic test can be useful for individuals with a family history of Tay-Sachs disease or those who are planning to have children and want to assess their risk of passing on the disease. It can also be used for prenatal testing to determine if a fetus has inherited the mutation.
It is important to note that this test specifically analyzes the HEXA gene for mutations associated with Tay-Sachs disease and does not provide information about other genetic conditions or diseases. Additionally, genetic testing should be done in consultation with a healthcare professional or genetic counselor who can help interpret the results and provide appropriate guidance and support.
Test Components and Price
- Test Name: HEXA Gene Tay-Sachs disease Genetic Test
- Components: Blood or Extracted DNA or One drop Blood on FTA Card
- Price: 3200.0 AED
Report Delivery
Reports for the HEXA Gene Tay-Sachs disease Genetic Test are typically delivered within 3 to 4 weeks.
Method
The HEXA Gene Tay-Sachs disease Genetic Test utilizes NGS technology for analysis.
Test Type
The HEXA Gene Tay-Sachs disease Genetic Test falls under the category of Metabolic Disorders.
Doctor
The test can be ordered by a General Physician.
Test Department
The test is conducted by the Genetics department at DNA Labs UAE.
Pre Test Information
Prior to undergoing the HEXA Gene Tay-Sachs disease NGS Genetic DNA Test, it is recommended to provide the clinical history of the patient. Additionally, a Genetic Counselling session is conducted to draw a pedigree chart of family members affected with Tay-Sachs disease.
| Test Name | HEXA Gene Tay-Sachs disease Genetic Test |
|---|---|
| Components | |
| Price | 3200.0 AED |
| Sample Condition | Blood or Extracted DNA or One drop Blood on FTA Card |
| Report Delivery | 3 to 4 Weeks |
| Method | NGS Technology |
| Test type | Metabolic Disorders |
| Doctor | General Physician |
| Test Department: | Genetics |
| Pre Test Information | Clinical History of Patient who is going for HEXA Gene Tay-Sachs disease NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Tay-Sachs disease |
| Test Details |
HEXA Gene Tay-Sachs disease NGS Genetic Test is a genetic test that uses Next-Generation Sequencing (NGS) technology to analyze the HEXA gene for mutations associated with Tay-Sachs disease. Tay-Sachs disease is a rare genetic disorder characterized by the progressive destruction of nerve cells in the brain and spinal cord. The HEXA gene provides instructions for producing an enzyme called beta-hexosaminidase A, which is responsible for breaking down a fatty substance called GM2 ganglioside. Mutations in the HEXA gene can lead to a deficiency or complete absence of this enzyme, resulting in the accumulation of GM2 ganglioside in the nerve cells and causing the symptoms of Tay-Sachs disease. The HEXA Gene Tay-Sachs disease NGS Genetic Test involves obtaining a DNA sample, typically through a blood or saliva sample, and analyzing it using NGS technology. NGS allows for the simultaneous sequencing of multiple genes, including the HEXA gene, to identify any genetic variants or mutations. By detecting mutations in the HEXA gene, this test can determine if an individual carries a mutation associated with Tay-Sachs disease. Carriers of a single mutation are typically unaffected by the disease but can pass the mutation on to their children. If both parents are carriers, there is a 25% chance with each pregnancy that their child will inherit two copies of the mutated gene and develop Tay-Sachs disease. This genetic test can be useful for individuals with a family history of Tay-Sachs disease or those who are planning to have children and want to assess their risk of passing on the disease. It can also be used for prenatal testing to determine if a fetus has inherited the mutation. It is important to note that this test specifically analyzes the HEXA gene for mutations associated with Tay-Sachs disease and does not provide information about other genetic conditions or diseases. Additionally, genetic testing should be done in consultation with a healthcare professional or genetic counselor who can help interpret the results and provide appropriate guidance and support. |
