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Hereditary Persistence of Fetal Hemoglobin HPFH Test Cost

Original price was: 1,600 د.إ.Current price is: 1,200 د.إ.

-25%

The Hereditary Persistence of Fetal Hemoglobin (HPFH) test is a specialized genetic analysis designed to detect mutations associated with the continued production of fetal hemoglobin (HbF) into adulthood. Fetal hemoglobin is a type of hemoglobin that is normally present in fetuses and infants, providing efficient oxygen transport from the mother’s bloodstream. In individuals with HPFH, this form of hemoglobin persists at elevated levels beyond infancy, which can have implications for certain blood disorders, including sickle cell disease and beta-thalassemia.

The test involves collecting a blood sample from the individual, which is then analyzed for specific genetic markers indicative of HPFH. These markers include mutations in the HBG1 and HBG2 genes, among others, that are responsible for the regulation of hemoglobin production. Identifying the presence of these mutations can aid in the diagnosis of HPFH, inform treatment strategies for related hemoglobinopathies, and provide valuable information for genetic counseling.

In the United Arab Emirates, the HPFH test is available at DNA Labs UAE, a leading facility in genetic diagnostics. The cost of the test is 1200 AED, making it accessible for individuals seeking to understand their genetic predisposition to persistent fetal hemoglobin production and its implications for their health. DNA Labs UAE employs state-of-the-art technology and expertise to ensure accurate and reliable test results, offering a crucial resource for patients and healthcare providers in managing and understanding hemoglobin-related disorders.

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Hereditary Persistence of Fetal Hemoglobin (HPFH) Test

Welcome to DNA Labs UAE, where we offer the Hereditary Persistence of Fetal Hemoglobin (HPFH) Test. This test is designed to detect the presence of HPFH and provide valuable insights into your genetic makeup. Read on to learn more about the test, its components, cost, symptoms, diagnosis, and more.

Test Details

The Hereditary Persistence of Fetal Hemoglobin (HPFH) Test is a genetic test that helps identify the continued production of fetal hemoglobin (HbF) into adulthood. Normally, fetal hemoglobin is gradually replaced by adult hemoglobin (HbA) shortly after birth. However, individuals with HPFH do not experience this switch, resulting in higher-than-normal levels of HbF in their blood.

HPFH is typically caused by mutations in genes that regulate hemoglobin production. There are various types of HPFH, with HPFH-1 and HPFH-2 being the most common. HPFH-1 is caused by mutations in the gamma-globin gene, while HPFH-2 is caused by mutations in the beta-globin gene.

Individuals with HPFH may experience clinical benefits due to the persistence of fetal hemoglobin. Fetal hemoglobin has a higher affinity for oxygen than adult hemoglobin, which can improve oxygen delivery to tissues. This can be particularly advantageous for individuals with conditions such as sickle cell disease and beta-thalassemia, where increased levels of fetal hemoglobin can help mitigate the effects of the underlying disease.

Test Components

The Hereditary Persistence of Fetal Hemoglobin (HPFH) Test requires the following components:

  • Sterile container
  • Sterile Normal Saline Container
  • EDTA Vacutainer (2ml)

Test Cost

The cost of the Hereditary Persistence of Fetal Hemoglobin (HPFH) Test is 1200.0 AED.

Sample Condition

The test can be performed using amniotic fluid, chorionic villi, or cord blood as the sample.

Report Delivery

Once the sample is collected, the report will be delivered within 7-8 days.

Method

The Hereditary Persistence of Fetal Hemoglobin (HPFH) Test is conducted using the End Point PCR method.

Test Type

The Hereditary Persistence of Fetal Hemoglobin (HPFH) Test falls under the category of Genetics.

Referring Doctor

The test can be ordered by a General Physician.

Test Department

The Hereditary Persistence of Fetal Hemoglobin (HPFH) Test is conducted in our Test Department.

Pre Test Information

A Doctor’s prescription is required for the Hereditary Persistence of Fetal Hemoglobin (HPFH) Test. However, prescriptions are not applicable for surgery and pregnancy cases or individuals planning to travel abroad.

Diagnosis and Treatment

Diagnosis of HPFH is typically done through genetic testing, which can identify the specific mutation causing the condition. Treatment for HPFH is generally not required, as it is a benign condition. However, in certain cases where HPFH is associated with another hemoglobin disorder, treatment may be directed towards managing the underlying condition.

At DNA Labs UAE, we are committed to providing accurate and reliable genetic testing services. Contact us today to schedule your Hereditary Persistence of Fetal Hemoglobin (HPFH) Test and gain valuable insights into your genetic makeup.

Test Name Hereditary persistence of fetal hemoglobin HPFH Test
Components Sterile container / Sterile Normal Saline Container / EDTA Vacutainer (2ml)
Price 1200.0 AED
Sample Condition Amniotic fluid \/ Chorionic villi \/ Cord blood
Report Delivery 7-8 days
Method End Point PCR
Test type Genetics
Doctor General Physician
Test Department:
Pre Test Information Hereditary persistence of fetal hemoglobin (HPFH) can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.
Test Details

Hereditary persistence of fetal hemoglobin (HPFH) is a genetic condition characterized by the continued production of fetal hemoglobin (HbF) into adulthood. Normally, fetal hemoglobin is gradually replaced by adult hemoglobin (HbA) shortly after birth. However, in individuals with HPFH, the switch from HbF to HbA does not occur, resulting in a higher-than-normal level of HbF in the blood.

HPFH is typically caused by mutations in the genes that regulate the production of hemoglobin. There are several types of HPFH, each associated with mutations in different genes. The most common types are HPFH-1 and HPFH-2, which are caused by mutations in the gamma-globin gene and the beta-globin gene, respectively.

The persistence of fetal hemoglobin in individuals with HPFH can have clinical benefits. Fetal hemoglobin has a higher affinity for oxygen than adult hemoglobin, which means that individuals with HPFH may have improved oxygen delivery to tissues. This can be particularly beneficial in certain conditions, such as sickle cell disease and beta-thalassemia, where increased levels of fetal hemoglobin can help mitigate the effects of the underlying disease.

HPFH is typically inherited in an autosomal dominant manner, which means that an affected individual has a 50% chance of passing the condition on to each of their children. However, the severity and clinical impact of HPFH can vary widely between individuals, even within the same family.

Diagnosis of HPFH is typically done through genetic testing, which can identify the specific mutation causing the condition. Treatment for HPFH is generally not required, as it is a benign condition. However, in certain cases, such as when HPFH is associated with another hemoglobin disorder, treatment may be directed towards managing the underlying condition.

SKU: TEST-5361