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Heparin-Induced Thrombocytopenia HIT Anti-Platelet Factor 4-Heparin PF4-H IgG Quantitative Test Cost

Original price was: 3,110 د.إ.Current price is: 2,800 د.إ.

-10%

Heparin-Induced Thrombocytopenia (HIT) is a serious immune-mediated adverse reaction to heparin, a common anticoagulant medication. This condition arises when the body generates antibodies against a complex formed between heparin and Platelet Factor 4 (PF4), leading to a paradoxical reduction in platelet count and an increased risk of thrombosis. The Anti-Platelet Factor 4-Heparin (PF4-H) IgG Quantitative Test is a specialized diagnostic assay designed to detect the presence and quantify the levels of these specific antibodies in the blood.

This test is crucial for the diagnosis and management of patients suspected of having HIT, as it helps in confirming the presence of PF4-H antibodies, thereby guiding appropriate treatment decisions. Given the potential for severe complications associated with HIT, including deep vein thrombosis, pulmonary embolism, and stroke, accurate and timely diagnosis is paramount.

In the UAE, the Anti-PF4-H IgG Quantitative Test is available at DNA Labs, a leading laboratory known for its advanced diagnostic services. The cost of the test is 2800 AED, reflecting the sophisticated nature of the assay and the expertise required to perform it. DNA Labs UAE ensures precise results, providing essential information for clinicians to manage patients who have or are at risk of developing HIT due to heparin therapy.

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HEPARIN INDUCED THROMBOCYTOPENIA (HIT) – Anti Platelet Factor 4-Heparin (PF4-H) IgG Quantitative Test

Test Cost: AED 2800.0

Test Components:

  • Price: AED 2800.0

Sample Condition:

3 mL whole blood in 1 Blue Top (Sodium Citrate) tube. Mix thoroughly by inversion. Transport to Lab within 4 hours. If this is not possible, make PPP within 1 hour of collection as follows: Centrifuge sample at 3600 rpm for 15 min. & transfer supernatant to a clean plastic tube. Centrifuge this supernatant again at 3600 rpm for 15 mins. & finally transfer the supernatant (PPP) to 1 labelled, clean plastic screw capped vial. FREEZE IMMEDIATELY. Ship frozen. DO NOT THAW. Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory.

Report Delivery:

Sample Daily by 11 am; Report Same day

Method:

Chemiluminescent Immunoassay (CLIA)

Test Type:

Disorders of Coagulation

Doctor:

Cardiologist, Hematologist

Test Department:

COAGULATION

Pre Test Information:

Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory.

Test Details:

Heparin-induced thrombocytopenia (HIT) is a condition characterized by a decrease in platelet count caused by the immune system’s response to heparin, a commonly used blood thinner. It is important to diagnose HIT promptly as it can lead to serious complications such as blood clots.

The anti-platelet factor 4-heparin (PF4-H) IgG quantitative test is a laboratory test used to diagnose HIT. It measures the levels of anti-PF4-H antibodies in the blood, specifically IgG antibodies. These antibodies are produced by the immune system in response to the formation of complexes between heparin and platelet factor 4 (PF4), a protein found in platelets.

The test involves taking a blood sample from the patient and measuring the levels of anti-PF4-H IgG antibodies using a quantitative method, such as enzyme-linked immunosorbent assay (ELISA). The results are reported as a numerical value, indicating the concentration of antibodies in the blood.

A positive result, indicating high levels of anti-PF4-H IgG antibodies, suggests the presence of HIT. However, it is important to note that a positive result alone is not sufficient for diagnosis. Clinical assessment, including the patient’s symptoms and other laboratory tests, is also necessary to confirm the diagnosis.

The anti-PF4-H IgG quantitative test is a valuable tool in diagnosing HIT and guiding appropriate treatment decisions. It helps differentiate HIT from other causes of thrombocytopenia and allows for timely management to prevent complications associated with this condition.

Test Name HEPARIN INDUCED THROMBOCYTOPENIA HIT ANTI PLATELET FACTOR 4-HEPARIN PF4-H IgG QUANTITATIVE Test
Components
Price 2800.0 AED
Sample Condition 3 mL whole blood in 1 Blue Top (Sodium Citrate) tube. Mix thoroughly by inversion. Transport to Lab within 4 hours. If this is not possible, make PPP within 1 hour of collection as follows: Centrifuge sample at 3600 rpm for 15 min. & transfer supernatant to a clean plastic tube. Centrifuge this supernatant again at 3600 rpm for 15 mins. & finally transfer the supernatant (PPP) to 1 labelled, clean plastic screw capped vial. FREEZE IMMEDIATELY. Ship frozen. DO NOT THAW. Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory.
Report Delivery Sample Daily by 11 am; Report Same day
Method Chemiluminescent Imuunoassay (CLIA)
Test type Disorders of Coagulation
Doctor Cardiologist, Hematologist
Test Department: COAGULATION
Pre Test Information Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory.
Test Details

Heparin-induced thrombocytopenia (HIT) is a condition characterized by a decrease in platelet count caused by the immune system’s response to heparin, a commonly used blood thinner. It is important to diagnose HIT promptly as it can lead to serious complications such as blood clots.

The anti-platelet factor 4-heparin (PF4-H) IgG quantitative test is a laboratory test used to diagnose HIT. It measures the levels of anti-PF4-H antibodies in the blood, specifically IgG antibodies. These antibodies are produced by the immune system in response to the formation of complexes between heparin and platelet factor 4 (PF4), a protein found in platelets.

The test involves taking a blood sample from the patient and measuring the levels of anti-PF4-H IgG antibodies using a quantitative method, such as enzyme-linked immunosorbent assay (ELISA). The results are reported as a numerical value, indicating the concentration of antibodies in the blood.

A positive result, indicating high levels of anti-PF4-H IgG antibodies, suggests the presence of HIT. However, it is important to note that a positive result alone is not sufficient for diagnosis. Clinical assessment, including the patient’s symptoms and other laboratory tests, is also necessary to confirm the diagnosis.

The anti-PF4-H IgG quantitative test is a valuable tool in diagnosing HIT and guiding appropriate treatment decisions. It helps differentiate HIT from other causes of thrombocytopenia and allows for timely management to prevent complications associated with this condition.