FISH – t814 OR MYCIGH FOR BURKITT and NON-HODGKIN LYMPHOMA Test
Test Name: FISH – t814 OR MYCIGH FOR BURKITT and NON-HODGKIN LYMPHOMA Test
Test Cost: AED 1200.0
Test Components: 5 mL (3 mL min.) whole blood OR 4 mL (2 mL min.) Bone Marrow from 2 Green Top (Sodium Heparin) tubes. Ship at 18-22°C. DO NOT FREEZE.
Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.
Report Delivery: Sample Daily by 4 pm; Report 4 Working days
Method: FISH
Test Type: Cancer
Doctor: Oncologist, Hematologist
Test Department: CYTOGENETICS
Pre Test Information: Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.
Test Details
FISH (Fluorescence In Situ Hybridization) is a molecular cytogenetic technique used to detect and locate specific DNA sequences on chromosomes. It is commonly used in cancer diagnostics to detect genetic abnormalities, such as translocations, deletions, or amplifications, which can be indicative of certain types of cancer.
t(8;14) is a specific translocation commonly found in Burkitt lymphoma, a type of non-Hodgkin lymphoma. This translocation involves the fusion of the MYC gene on chromosome 8 with the immunoglobulin heavy chain (IGH) gene on chromosome 14. The resulting abnormal fusion protein promotes uncontrolled cell growth and division, leading to the development of cancer.
Therefore, performing FISH analysis for the t(8;14) translocation or MYC/IGH fusion is a useful diagnostic test for identifying Burkitt lymphoma or certain types of non-Hodgkin lymphoma. This test helps confirm the presence of the specific genetic abnormality associated with these diseases and aids in the accurate diagnosis and classification of the lymphoma.
Test Name | FISH – t814 OR MYCIGH FOR BURKITT and NON-HODGKIN LYMPHOMA Test |
---|---|
Components | |
Price | 1200.0 AED |
Sample Condition | 5 mL (3 mL min.) whole blood OR 4 mL (2 mL min.) Bone Marrow from 2 Green Top (Sodium Heparin) tubes. Ship at 18-22?\u00f8C. DO NOT FREEZE.Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory. |
Report Delivery | Sample Daily by 4 pm; Report 4 Working days |
Method | FISH |
Test type | Cancer |
Doctor | Oncologist, Hematologist |
Test Department: | CYTOGENETICS |
Pre Test Information | Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory. |
Test Details |
FISH (Fluorescence In Situ Hybridization) is a molecular cytogenetic technique used to detect and locate specific DNA sequences on chromosomes. It is commonly used in cancer diagnostics to detect genetic abnormalities, such as translocations, deletions, or amplifications, which can be indicative of certain types of cancer. t(8;14) is a specific translocation commonly found in Burkitt lymphoma, a type of non-Hodgkin lymphoma. This translocation involves the fusion of the MYC gene on chromosome 8 with the immunoglobulin heavy chain (IGH) gene on chromosome 14. The resulting abnormal fusion protein promotes uncontrolled cell growth and division, leading to the development of cancer. Therefore, performing FISH analysis for the t(8;14) translocation or MYC/IGH fusion is a useful diagnostic test for identifying Burkitt lymphoma or certain types of non-Hodgkin lymphoma. This test helps confirm the presence of the specific genetic abnormality associated with these diseases and aids in the accurate diagnosis and classification of the lymphoma. |