FISH – t 1221 or LSI TELAML1 Test
Are you looking for information about the FISH – t 1221 or LSI TELAML1 Test? Look no further! DNA Labs UAE offers this test at a cost of AED 1200.0. This test is used for the diagnosis of leukemia and is commonly referred to by oncologists and hematologists.
Test Details
The FISH – t(1221) test is a type of fluorescence in situ hybridization (FISH) test that is used to detect a specific chromosomal translocation known as t(12;21). This translocation is commonly found in pediatric acute lymphoblastic leukemia (ALL) and is associated with a more favorable prognosis. On the other hand, the LSI TEL/AML1 test is also a FISH test that detects a different chromosomal translocation known as t(12;21)(p13;q22). This translocation is specifically associated with B-cell precursor ALL and results in the fusion of the TEL (ETV6) and AML1 (RUNX1) genes.
Both tests are molecular diagnostic tools used in the evaluation of leukemia patients, specifically in the detection of specific chromosomal abnormalities. The FISH – t(1221) test is primarily used to detect the t(12;21) translocation, while the LSI TEL/AML1 test is used to detect the TEL/AML1 fusion gene. It’s important to note that these tests are typically performed in conjunction with other diagnostic methods, such as cytogenetic analysis and molecular genetic testing, to provide a comprehensive assessment of the patient’s leukemia.
Test Cost and Sample Condition
The FISH – t 1221 or LSI TELAML1 Test is priced at AED 1200.0. The sample condition required for this test is 5 mL (3 mL min.) whole blood OR 4 mL (2 mL min.) Bone Marrow from 2 Green Top (Sodium Heparin) tubes. The sample should be shipped at 18-22°C and should not be frozen. Additionally, a duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory for this test.
Report Delivery and Test Type
The report for the FISH – t 1221 or LSI TELAML1 Test is delivered daily by 4 pm. The turnaround time for the report is 4 working days. The test type is categorized under Leukemia and is conducted in the CYTOGENETICS department.
Pre Test Information
Prior to undergoing the FISH – t 1221 or LSI TELAML1 Test, it is important to fill out the Chromosome & FISH analysis Requisition Form (Form 17) completely. This form is mandatory for the test.
Conclusion
The FISH – t 1221 or LSI TELAML1 Test is an important tool in the diagnosis and evaluation of leukemia patients. It helps detect specific chromosomal abnormalities associated with pediatric acute lymphoblastic leukemia (ALL) and provides valuable prognostic information. If you are an oncologist or hematologist, consider referring your patients to DNA Labs UAE for this test. With a cost of AED 1200.0 and a comprehensive report delivery, DNA Labs UAE ensures accurate and timely results.
Test Name | FISH – t 1221 or LSI TELAML1 Test |
---|---|
Components | |
Price | 1200.0 AED |
Sample Condition | 5 mL (3 mL min.) whole blood OR 4 mL (2 mL min.) Bone Marrow from 2 Green Top (Sodium Heparin) tubes. Ship at 18-22?\u00f8C. DO NOT FREEZE.Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory. |
Report Delivery | Sample Daily by 4 pm; Report 4 Working days |
Method | FISH |
Test type | Leukemia |
Doctor | Oncologist, Hematologist |
Test Department: | CYTOGENETICS |
Pre Test Information | Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory. |
Test Details |
The FISH – t(1221) test is a type of fluorescence in situ hybridization (FISH) test that is used to detect a specific chromosomal translocation known as t(12;21). This translocation is commonly found in pediatric acute lymphoblastic leukemia (ALL) and is associated with a more favorable prognosis. On the other hand, the LSI TEL/AML1 test is also a FISH test that detects a different chromosomal translocation known as t(12;21)(p13;q22). This translocation is specifically associated with B-cell precursor ALL and results in the fusion of the TEL (ETV6) and AML1 (RUNX1) genes. The presence of this fusion gene is considered a favorable prognostic marker in pediatric ALL. Both tests are molecular diagnostic tools used in the evaluation of leukemia patients, specifically in the detection of specific chromosomal abnormalities. The FISH – t(1221) test is primarily used to detect the t(12;21) translocation, while the LSI TEL/AML1 test is used to detect the TEL/AML1 fusion gene. It’s important to note that these tests are typically performed in conjunction with other diagnostic methods, such as cytogenetic analysis and molecular genetic testing, to provide a comprehensive assessment of the patient’s leukemia. The results of these tests can help guide treatment decisions and provide valuable prognostic information. |