FISH – SYNOVIAL SARCOMA SS18 SYT 18q11.2 GENE REARRANGEMENT Test
Test Name: FISH – SYNOVIAL SARCOMA SS18 SYT 18q11.2 GENE REARRANGEMENT Test
Components: Price: 2010.0 AED
Sample Condition: Submit Formalin fixed paraffin embedded tissue block. Ship at room temperature. Tissue block must contain 10% tumor tissue. Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.
Report Delivery: Sample Daily by 4 pm; Report 4 Working days
Method: FISH
Test type: Cancer
Doctor: Oncologist
Test Department: CYTOGENETICS
Pre Test Information: Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.
Test Details
The FISH (Fluorescence In Situ Hybridization) test for synovial sarcoma is used to detect a specific gene rearrangement involving the SS18/SYT gene on chromosome 18q11.2.
Synovial sarcoma is a rare type of soft tissue sarcoma that usually affects young adults. It is characterized by a specific translocation between chromosomes X and 18, resulting in a fusion of the SS18 gene on chromosome 18 with the SYT gene on the X chromosome. This gene rearrangement is present in about 90% of synovial sarcoma cases.
The FISH test utilizes fluorescently labeled DNA probes that specifically bind to the SS18/SYT fusion gene. By visualizing the fluorescent signals under a microscope, the presence of the gene rearrangement can be identified. If the SS18/SYT fusion gene is detected, it confirms the diagnosis of synovial sarcoma.
The FISH test is a valuable diagnostic tool for synovial sarcoma, as it provides a definitive and specific result. It can be performed on a tissue sample obtained through a biopsy or surgical resection. The results of the FISH test can help guide treatment decisions and prognosis for patients with synovial sarcoma.
| Test Name | FISH – SYNOVIAL SARCOMA SS18 SYT 18q11.2 GENE REARRANGEMENT Test |
|---|---|
| Components | |
| Price | 2010.0 AED |
| Sample Condition | Submit Formalin fixed paraffin embedded tissue block. Ship at room temperature. Tissue block must contain 10% tumor tissue. Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory. |
| Report Delivery | Sample Daily by 4 pm; Report 4 Working days |
| Method | FISH |
| Test type | Cancer |
| Doctor | Oncologist |
| Test Department: | CYTOGENETICS |
| Pre Test Information | Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory. |
| Test Details | The FISH (Fluorescence In Situ Hybridization) test for synovial sarcoma is used to detect a specific gene rearrangement involving the SS18/SYT gene on chromosome 18q11.2. Synovial sarcoma is a rare type of soft tissue sarcoma that usually affects young adults. It is characterized by a specific translocation between chromosomes X and 18, resulting in a fusion of the SS18 gene on chromosome 18 with the SYT gene on the X chromosome. This gene rearrangement is present in about 90% of synovial sarcoma cases. The FISH test utilizes fluorescently labeled DNA probes that specifically bind to the SS18/SYT fusion gene. By visualizing the fluorescent signals under a microscope, the presence of the gene rearrangement can be identified. If the SS18/SYT fusion gene is detected, it confirms the diagnosis of synovial sarcoma. The FISH test is a valuable diagnostic tool for synovial sarcoma, as it provides a definitive and specific result. It can be performed on a tissue sample obtained through a biopsy or surgical resection. The results of the FISH test can help guide treatment decisions and prognosis for patients with synovial sarcoma. |
