FISH – MYCN AMPLIFICATION Test
Test Cost: AED 2040.0
Symptoms, Diagnosis, and Test Details
At DNA Labs UAE, we offer the FISH – MYCN amplification test, a diagnostic test used to detect the amplification of the MYCN gene in cancer cells. This test is particularly important for patients with neuroblastoma, a type of childhood cancer.
Test Components and Price
The FISH – MYCN amplification test is priced at AED 2040.0. To conduct the test, we require a formalin-fixed paraffin-embedded tissue block containing at least 10% tumor tissue. Please ship the sample at room temperature. Additionally, it is mandatory to fill out the Chromosome & FISH analysis Requisition Form (Form 17).
Report Delivery and Turnaround Time
You can expect your test results to be delivered within 4 working days. Samples are received daily by 4 pm.
Method and Test Type
The FISH – MYCN amplification test utilizes the FISH method, which stands for fluorescence in situ hybridization. This technique allows us to visualize specific DNA sequences within cells. By applying fluorescently labeled DNA probes complementary to the MYCN gene, we can detect the amplification of this gene in cancer cells.
Doctor and Test Department
The FISH – MYCN amplification test is conducted by our experienced oncologist in the CYTOGENETICS department.
Pre Test Information
Prior to conducting the test, please ensure that the Chromosome & FISH analysis Requisition Form (Form 17) is duly filled and submitted.
Importance and Applications
The FISH – MYCN amplification test plays a crucial role in determining the prognosis and treatment options for patients with neuroblastoma. MYCN amplification is associated with a more aggressive form of the disease and poorer outcomes. By identifying MYCN amplification, we can guide treatment decisions, such as the use of more intensive therapies. This test provides valuable information about the genetic characteristics of the cancer cells, aiding in the diagnosis and management of neuroblastoma patients.
| Test Name | FISH – MYCN AMPLIFICATION Test |
|---|---|
| Components | |
| Price | 2040.0 AED |
| Sample Condition | Submit Formalin fixed paraffin embedded tissue block. Ship at room temperature. Tissue block must contain 10% tumor tissue. Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory. |
| Report Delivery | Sample Daily by 4 pm; Report 4 Working days |
| Method | FISH |
| Test type | Cancer |
| Doctor | Oncologist |
| Test Department: | CYTOGENETICS |
| Pre Test Information | Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory. |
| Test Details |
The FISH – MYCN amplification test is a diagnostic test used to detect the amplification of the MYCN gene in cancer cells. MYCN amplification is a genetic alteration that is commonly found in neuroblastoma, a type of childhood cancer. FISH stands for fluorescence in situ hybridization, which is a technique used to visualize specific DNA sequences within cells. In this test, fluorescently labeled DNA probes that are complementary to the MYCN gene are applied to the cancer cells. If the MYCN gene is amplified, the probes will bind to multiple copies of the gene, resulting in a strong fluorescent signal. The FISH – MYCN amplification test is important for determining the prognosis and treatment options for patients with neuroblastoma. MYCN amplification is associated with a more aggressive form of the disease and poorer outcomes. Therefore, identifying MYCN amplification can help guide treatment decisions, such as the use of more intensive therapies. Overall, the FISH – MYCN amplification test plays a crucial role in the diagnosis and management of neuroblastoma patients by providing valuable information about the genetic characteristics of the cancer cells. |
