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FISH – inv16 or LSI CBFB Test

1,010 د.إ

-10%

The FISH (Fluorescence In Situ Hybridization) – inv16 or LSI CBFB Test is a specialized genetic test performed to detect the inversion of chromosome 16, specifically targeting the CBFB gene. This particular genetic alteration is commonly associated with certain types of leukemia, most notably acute myeloid leukemia (AML). The test utilizes fluorescent probes to bind to specific DNA sequences on chromosome 16, allowing for the visualization of the inversion under a fluorescence microscope.

Conducted at DNA Labs UAE, a leading facility in genetic diagnostics, the test is pivotal in the diagnosis and management of patients suspected of having or known to have leukemia. By identifying the inv16 or CBFB gene rearrangement, clinicians can better determine prognosis, tailor treatment plans to the individual patient, and monitor response to therapy.

The cost of the FISH – inv16 or LSI CBFB Test at DNA Labs UAE is 1010 AED. Given the complexity of the test and the specialized equipment and expertise required, this cost reflects the comprehensive analysis and reliable results provided by the laboratory. Patients and healthcare providers considering this test should consult with a specialist to understand its implications fully and how it fits into the broader diagnostic and treatment plan.

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FISH – inv16 OR LSI CBFB Test

Test Name: FISH – inv16 OR LSI CBFB Test

Components: Price: 1010.0 AED

Sample Condition: 5 mL (3 mL min.) whole blood OR 4 mL (2 mL min.) Bone Marrow from 2 Green Top (Sodium Heparin) tubes. Ship at 18-22°C. DO NOT FREEZE.

Requisition Form: Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.

Report Delivery: Sample Daily by 4 pm; Report 4 Working days

Method: FISH

Test type: Cancer

Doctor: Oncologist, Hematologist

Test Department: CYTOGENETICS

Pre Test Information: Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.

Test Details:

FISH (Fluorescence In Situ Hybridization) – inv(16) or LSI CBFB Test is a molecular diagnostic test used to detect a specific genetic abnormality known as inv(16) or CBFB-MYH11 fusion gene in certain types of leukemia. The inv(16) or inversion 16 is a chromosomal abnormality that occurs in a subtype of acute myeloid leukemia (AML) called acute myelomonocytic leukemia (AMML). It involves the rearrangement of genetic material on chromosome 16, leading to the fusion of the CBFB (core-binding factor subunit beta) gene with the MYH11 (myosin heavy chain 11) gene.

The LSI CBFB Test is a type of FISH test that uses fluorescently labeled DNA probes specific to the CBFB gene and the MYH11 gene. These probes bind to the respective genes on the patient’s chromosomes and emit fluorescent signals that can be visualized under a fluorescence microscope. The presence of the CBFB-MYH11 fusion gene is indicated by the presence of a specific fluorescent signal pattern.

The FISH – inv(16) or LSI CBFB Test is used to confirm the diagnosis of inv(16)-positive AMML and to monitor the response to treatment. It is a highly sensitive and specific test that can detect even low levels of the CBFB-MYH11 fusion gene in leukemia cells. The results of this test can help guide treatment decisions and prognosis for patients with inv(16)-positive AMML.

Test Name FISH – inv16 OR LSI CBFB Test
Components
Price 1010.0 AED
Sample Condition 5 mL (3 mL min.) whole blood OR 4 mL ( 2 mL min.) Bone Marrow from 2 Green Top (Sodium Heparin) tubes. Ship at 18-22?\u00f8C. DO NOT FREEZE. Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.
Report Delivery Sample Daily by 4 pm; Report 4 Working days
Method FISH
Test type Cancer
Doctor Oncologist, Hematologist
Test Department: CYTOGENETICS
Pre Test Information Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.
Test Details

FISH (Fluorescence In Situ Hybridization) – inv(16) or LSI CBFB Test is a molecular diagnostic test used to detect a specific genetic abnormality known as inv(16) or CBFB-MYH11 fusion gene in certain types of leukemia.

The inv(16) or inversion 16 is a chromosomal abnormality that occurs in a subtype of acute myeloid leukemia (AML) called acute myelomonocytic leukemia (AMML). It involves the rearrangement of genetic material on chromosome 16, leading to the fusion of the CBFB (core-binding factor subunit beta) gene with the MYH11 (myosin heavy chain 11) gene.

The LSI CBFB Test is a type of FISH test that uses fluorescently labeled DNA probes specific to the CBFB gene and the MYH11 gene. These probes bind to the respective genes on the patient’s chromosomes and emit fluorescent signals that can be visualized under a fluorescence microscope. The presence of the CBFB-MYH11 fusion gene is indicated by the presence of a specific fluorescent signal pattern.

The FISH – inv(16) or LSI CBFB Test is used to confirm the diagnosis of inv(16)-positive AMML and to monitor the response to treatment. It is a highly sensitive and specific test that can detect even low levels of the CBFB-MYH11 fusion gene in leukemia cells. The results of this test can help guide treatment decisions and prognosis for patients with inv(16)-positive AMML.