FISH – inv16 OR LSI CBFB Test
Test Name: FISH – inv16 OR LSI CBFB Test
Components: Price: 1010.0 AED
Sample Condition: 5 mL (3 mL min.) whole blood OR 4 mL (2 mL min.) Bone Marrow from 2 Green Top (Sodium Heparin) tubes. Ship at 18-22°C. DO NOT FREEZE.
Requisition Form: Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.
Report Delivery: Sample Daily by 4 pm; Report 4 Working days
Method: FISH
Test type: Cancer
Doctor: Oncologist, Hematologist
Test Department: CYTOGENETICS
Pre Test Information: Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.
Test Details:
FISH (Fluorescence In Situ Hybridization) – inv(16) or LSI CBFB Test is a molecular diagnostic test used to detect a specific genetic abnormality known as inv(16) or CBFB-MYH11 fusion gene in certain types of leukemia. The inv(16) or inversion 16 is a chromosomal abnormality that occurs in a subtype of acute myeloid leukemia (AML) called acute myelomonocytic leukemia (AMML). It involves the rearrangement of genetic material on chromosome 16, leading to the fusion of the CBFB (core-binding factor subunit beta) gene with the MYH11 (myosin heavy chain 11) gene.
The LSI CBFB Test is a type of FISH test that uses fluorescently labeled DNA probes specific to the CBFB gene and the MYH11 gene. These probes bind to the respective genes on the patient’s chromosomes and emit fluorescent signals that can be visualized under a fluorescence microscope. The presence of the CBFB-MYH11 fusion gene is indicated by the presence of a specific fluorescent signal pattern.
The FISH – inv(16) or LSI CBFB Test is used to confirm the diagnosis of inv(16)-positive AMML and to monitor the response to treatment. It is a highly sensitive and specific test that can detect even low levels of the CBFB-MYH11 fusion gene in leukemia cells. The results of this test can help guide treatment decisions and prognosis for patients with inv(16)-positive AMML.
| Test Name | FISH – inv16 OR LSI CBFB Test |
|---|---|
| Components | |
| Price | 1010.0 AED |
| Sample Condition | 5 mL (3 mL min.) whole blood OR 4 mL ( 2 mL min.) Bone Marrow from 2 Green Top (Sodium Heparin) tubes. Ship at 18-22?\u00f8C. DO NOT FREEZE. Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory. |
| Report Delivery | Sample Daily by 4 pm; Report 4 Working days |
| Method | FISH |
| Test type | Cancer |
| Doctor | Oncologist, Hematologist |
| Test Department: | CYTOGENETICS |
| Pre Test Information | Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory. |
| Test Details | FISH (Fluorescence In Situ Hybridization) – inv(16) or LSI CBFB Test is a molecular diagnostic test used to detect a specific genetic abnormality known as inv(16) or CBFB-MYH11 fusion gene in certain types of leukemia. The inv(16) or inversion 16 is a chromosomal abnormality that occurs in a subtype of acute myeloid leukemia (AML) called acute myelomonocytic leukemia (AMML). It involves the rearrangement of genetic material on chromosome 16, leading to the fusion of the CBFB (core-binding factor subunit beta) gene with the MYH11 (myosin heavy chain 11) gene. The LSI CBFB Test is a type of FISH test that uses fluorescently labeled DNA probes specific to the CBFB gene and the MYH11 gene. These probes bind to the respective genes on the patient’s chromosomes and emit fluorescent signals that can be visualized under a fluorescence microscope. The presence of the CBFB-MYH11 fusion gene is indicated by the presence of a specific fluorescent signal pattern. The FISH – inv(16) or LSI CBFB Test is used to confirm the diagnosis of inv(16)-positive AMML and to monitor the response to treatment. It is a highly sensitive and specific test that can detect even low levels of the CBFB-MYH11 fusion gene in leukemia cells. The results of this test can help guide treatment decisions and prognosis for patients with inv(16)-positive AMML. |
