FISH for Her-2 Neu Test
Cost: AED 2800.0
Test Name: FISH for Her-2 Neu Test
Components: Price 2800.0 AED
Sample Condition: Submit Formalin fixed paraffin embedded tissue block. Ship at room temperature. Tissue block must contain 10% tumor tissue. Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.
Report Delivery: Sample Daily by 4 pm; Report 4 Working days
Method: FISH
Test type: Cancer
Doctor: Oncologist
Test Department: CYTOGENETICS
Pre Test Information: Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.
FISH, or Fluorescence In Situ Hybridization, is a molecular genetic technique used to detect and locate specific DNA sequences on chromosomes. In the context of Her-2 Neu, FISH can be used to determine the amplification of the Her-2 Neu gene in breast cancer cells. Her-2 Neu, also known as Human Epidermal Growth Factor Receptor 2, is a protein that plays a role in cell growth and division.
In some breast cancer cases, the Her-2 Neu gene is amplified, leading to overexpression of the Her-2 Neu protein. This overexpression is associated with more aggressive tumor growth and a poorer prognosis. FISH for Her-2 Neu involves labeling a specific DNA probe with a fluorescent molecule and applying it to breast cancer cells. The probe is designed to bind to the Her-2 Neu gene, and if the gene is amplified, multiple copies of the probe will bind to the DNA. The fluorescence signal from the probe can then be visualized under a microscope, and the number of fluorescent signals indicates the level of Her-2 Neu gene amplification.
FISH for Her-2 Neu is commonly used as a diagnostic tool to determine the eligibility of breast cancer patients for targeted therapy with drugs like trastuzumab (Herceptin). Patients with Her-2 Neu gene amplification are more likely to respond to these targeted therapies and may have a better prognosis.
In summary, FISH for Her-2 Neu is a molecular genetic technique used to detect and quantify the amplification of the Her-2 Neu gene in breast cancer cells. It plays a crucial role in the diagnosis and treatment of breast cancer patients.
| Test Name | FISH for Her-2 Neu Test |
|---|---|
| Components | |
| Price | 2800.0 AED |
| Sample Condition | Submit Formalin fixed paraffin embedded tissue block. Ship at room temperature. Tissue block must contain 10% tumor tissue. Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory. |
| Report Delivery | Sample Daily by 4 pm; Report 4 Working days |
| Method | FISH |
| Test type | Cancer |
| Doctor | Oncologist |
| Test Department: | CYTOGENETICS |
| Pre Test Information | Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory. |
| Test Details | FISH, or Fluorescence In Situ Hybridization, is a molecular genetic technique used to detect and locate specific DNA sequences on chromosomes. In the context of Her-2 Neu, FISH can be used to determine the amplification of the Her-2 Neu gene in breast cancer cells. Her-2 Neu, also known as Human Epidermal Growth Factor Receptor 2, is a protein that plays a role in cell growth and division. In some breast cancer cases, the Her-2 Neu gene is amplified, leading to overexpression of the Her-2 Neu protein. This overexpression is associated with more aggressive tumor growth and a poorer prognosis. FISH for Her-2 Neu involves labeling a specific DNA probe with a fluorescent molecule and applying it to breast cancer cells. The probe is designed to bind to the Her-2 Neu gene, and if the gene is amplified, multiple copies of the probe will bind to the DNA. The fluorescence signal from the probe can then be visualized under a microscope, and the number of fluorescent signals indicates the level of Her-2 Neu gene amplification. FISH for Her-2 Neu is commonly used as a diagnostic tool to determine the eligibility of breast cancer patients for targeted therapy with drugs like trastuzumab (Herceptin). Patients with Her-2 Neu gene amplification are more likely to respond to these targeted therapies and may have a better prognosis. In summary, FISH for Her-2 Neu is a molecular genetic technique used to detect and quantify the amplification of the Her-2 Neu gene in breast cancer cells. It plays a crucial role in the diagnosis and treatment of breast cancer patients. |
