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Fish – Follicular Lymphoma IGHBCL2 t1418 Test Cost

Original price was: 1,690 د.إ.Current price is: 1,520 د.إ.

-10%

The Fish – Follicular Lymphoma IGHBCL2 t(14;18) Test is a specialized diagnostic procedure designed to identify the presence of a specific chromosomal translocation, t(14;18)(q32;q21), which is commonly associated with follicular lymphoma. This translocation results in the juxtaposition of the BCL2 gene on chromosome 18 to the immunoglobulin heavy chain locus on chromosome 14. This genetic abnormality leads to the overexpression of the BCL2 protein, which plays a critical role in the pathogenesis of the disease by inhibiting apoptosis, thereby contributing to the survival of the lymphoma cells.

Performed at DNA Labs UAE, a state-of-the-art facility known for its advanced diagnostic services, this test utilizes Fluorescence In Situ Hybridization (FISH) technology. FISH is a cytogenetic technique that allows for the visualization of specific DNA sequences on chromosomes, making it an effective tool for detecting chromosomal abnormalities associated with various types of cancers, including follicular lymphoma.

The cost of the Fish – Follicular Lymphoma IGHBCL2 t(14;18) Test at DNA Labs UAE is 1520 AED. This test is crucial for the accurate diagnosis and management of patients suspected of having follicular lymphoma, as it provides essential genetic information that can guide treatment decisions and predict patient outcomes. Given the significance of the test in the clinical setting, it represents a valuable investment in the health and well-being of patients facing a potential diagnosis of follicular lymphoma.

Description

FISH – FOLLICULAR LYMPHOMA IGHBCL2 t1418 Test

Test Name: FISH – FOLLICULAR LYMPHOMA IGHBCL2 t1418 Test

Components: Price: 1520.0 AED

Sample Condition: 4 mL (3 mL min.) whole blood OR 4 mL (2 mL min.) Bone marrow from 2 Green Top (Sodium Heparin) tubes. Ship at 18-22°C OR Lymph node biopsy (5×5 mm) in normal saline OR Formalin fixed paraffin embedded tissue block. Ship at room temperature. DO NOT FREEZE.

Requisition Form: Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.

Report Delivery: Sample Daily by 4 pm; Report 4 Working days

Method: FISH

Test type: Lymphomas

Doctor: Oncologist

Test Department: CYTOGENETICS

Pre Test Information: Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.

Test Details:

The FISH – Follicular Lymphoma (IGH/BCL2) t(14;18) test is a molecular diagnostic test used to detect a specific chromosomal translocation in follicular lymphoma. This translocation involves the genes IGH (Immunoglobulin heavy chain) and BCL2 (B-cell lymphoma 2), resulting in the fusion of these genes.

The t(14;18) translocation is found in approximately 85-90% of cases of follicular lymphoma, making it a useful diagnostic marker for this type of lymphoma. This translocation leads to the overexpression of the BCL2 protein, which prevents apoptosis (programmed cell death) and promotes the survival of lymphoma cells.

The FISH test uses fluorescently labeled DNA probes that specifically bind to the IGH and BCL2 genes. By examining the pattern of fluorescence under a microscope, the presence of the t(14;18) translocation can be detected. This test can be performed on a bone marrow or lymph node biopsy sample.

The FISH – Follicular Lymphoma (IGH/BCL2) t(14;18) test is important for confirming the diagnosis of follicular lymphoma and distinguishing it from other types of lymphomas. It can also be used to monitor disease progression and response to treatment.

It is important to note that this test is not used for screening or early detection of follicular lymphoma, but rather for confirming the diagnosis in individuals suspected to have the disease. It is typically ordered by a hematologist or oncologist as part of the diagnostic workup for lymphoma.

Test Name	FISH – FOLLICULAR LYMPHOMA IGHBCL2 t1418 Test
Components
Price	1520.0 AED
Sample Condition	4 mL (3 mL min.) whole blood OR 4 mL (2 mL min.) Bone marrow from 2 Green Top (Sodium Heparin) tubes. Ship at 18\u0192??22?\u00f8C OR Lymph node biopsy (5×5 mm) in normal saline OR Formalin fixed paraffin embedded tissue block. Ship at room temperature. DO NOT FREEZE. Duly filled Chromosome & FISH analysisRequisition Form (Form 17) is mandatory.
Report Delivery	Sample Daily by 4 pm; Report 4 Working days
Method	FISH
Test type	Lymphomas
Doctor	Oncologist
Test Department:	CYTOGENETICS
Pre Test Information	Duly filled Chromosome & FISH analysisRequisition Form (Form 17) is mandatory.
Test Details	The FISH – Follicular Lymphoma (IGH/BCL2) t(14;18) test is a molecular diagnostic test used to detect a specific chromosomal translocation in follicular lymphoma. This translocation involves the genes IGH (Immunoglobulin heavy chain) and BCL2 (B-cell lymphoma 2), resulting in the fusion of these genes. The t(14;18) translocation is found in approximately 85-90% of cases of follicular lymphoma, making it a useful diagnostic marker for this type of lymphoma. This translocation leads to the overexpression of the BCL2 protein, which prevents apoptosis (programmed cell death) and promotes the survival of lymphoma cells. The FISH test uses fluorescently labeled DNA probes that specifically bind to the IGH and BCL2 genes. By examining the pattern of fluorescence under a microscope, the presence of the t(14;18) translocation can be detected. This test can be performed on a bone marrow or lymph node biopsy sample. The FISH – Follicular Lymphoma (IGH/BCL2) t(14;18) test is important for confirming the diagnosis of follicular lymphoma and distinguishing it from other types of lymphomas. It can also be used to monitor disease progression and response to treatment. It is important to note that this test is not used for screening or early detection of follicular lymphoma, but rather for confirming the diagnosis in individuals suspected to have the disease. It is typically ordered by a hematologist or oncologist as part of the diagnostic workup for lymphoma.