Sale!

Familial Mediterranean Fever MEFV Full Gene Analysis Test Cost

Original price was: 9,600 د.إ.Current price is: 7,200 د.إ.

-25%

The Familial Mediterranean Fever (FMF) MEFV Full Gene Analysis Test is a comprehensive genetic screening designed to identify mutations in the MEFV gene, which are associated with Familial Mediterranean Fever. This condition is an inherited disorder that primarily affects individuals of Mediterranean and Middle Eastern descent, leading to recurrent fevers and painful inflammation of the abdomen, lungs, and joints. By analyzing the entire MEFV gene, this test can provide crucial information for the diagnosis, management, and treatment planning of FMF.

Conducted at DNA Labs UAE, a leading facility in genetic diagnostics, the test ensures high accuracy and reliability in results. The cost of the FMF MEFV Full Gene Analysis Test is 7200 AED, reflecting the comprehensive nature of the genetic analysis and the expertise required to interpret its findings. This test is particularly important for individuals with a family history of FMF or those exhibiting symptoms, as early detection can significantly improve the quality of life through targeted treatments and lifestyle adjustments.

Home  Sample collection service available

  • 100% accuaret Test Results
  • Ranked as Most trusted Genetic DNA Lab
  • This test is not intended for medical diagnosis or treatment
Guaranteed Safe Checkout

Familial Mediterranean Fever MEFV Full Gene Analysis Test Price 7200 AED in Dubai

Understanding Familial Mediterranean Fever (FMF)

Familial Mediterranean Fever (FMF) is an inherited autoinflammatory disorder primarily affecting individuals of Mediterranean descent, including those in the UAE. Characterized by recurrent episodes of fever, abdominal pain, chest pain, and arthritis, FMF can significantly impact the quality of life. The condition is caused by mutations in the MEFV gene, which encodes the protein pyrin. Pyrin plays a crucial role in controlling inflammation in the body. Mutations in this gene lead to uncontrolled inflammation, resulting in the symptoms observed in FMF.

The Role of MEFV Gene in FMF

The MEFV gene, located on chromosome 16, is responsible for producing the pyrin protein, which regulates inflammation by modulating the immune response. Mutations in the MEFV gene disrupt this regulation, causing the inflammatory episodes typical of FMF. Over 300 mutations in the MEFV gene have been identified, with specific mutations being more prevalent in certain populations.

Importance of MEFV Full Gene Analysis

MEFV full gene analysis involves sequencing the entire MEFV gene to identify any mutations present. This comprehensive approach offers several key benefits:

  1. Accurate Diagnosis: FMF symptoms can overlap with other autoinflammatory and autoimmune disorders, making accurate diagnosis challenging. MEFV full gene analysis provides a definitive diagnosis by identifying specific mutations responsible for FMF.
  2. Personalized Treatment Plans: Understanding the specific mutations in the MEFV gene allows healthcare providers to tailor treatment plans. Certain mutations may respond better to specific medications, ensuring more effective management of the condition.
  3. Family Planning and Genetic Counseling: For individuals with FMF or those who carry MEFV mutations, genetic counseling is crucial. MEFV full gene analysis provides essential information for family planning, helping individuals understand the risk of passing the condition to their children.
  4. Preventing Complications: Early and accurate diagnosis through MEFV full gene analysis can prevent complications such as amyloidosis, a condition where inflammatory proteins accumulate in organs, potentially leading to organ failure.

The Process of MEFV Full Gene Analysis

MEFV full gene analysis is typically conducted using a blood sample. The process involves several steps:

  1. Sample Collection: A healthcare professional collects a blood sample from the patient.
  2. DNA Extraction: The DNA is extracted from the blood sample in a laboratory.
  3. Sequencing: The MEFV gene is sequenced to identify any mutations. This involves reading the genetic code of the entire gene.
  4. Data Interpretation: Geneticists interpret the sequencing data to identify any mutations and their potential impact on protein function.
  5. Reporting: The results are compiled into a comprehensive report, detailing the identified mutations and their clinical significance.

Choosing the Right Facility for MEFV Full Gene Analysis in UAE

When considering MEFV full gene analysis, it is essential to choose a reputable facility with expertise in genetic testing and a track record of accurate results. Here are some factors to consider:

  1. Accreditation and Certification: Ensure the facility is accredited and certified by relevant health authorities.
  2. Expertise and Experience: Look for a facility with experienced geneticists and a history of conducting MEFV full gene analysis.
  3. Comprehensive Genetic Counseling: The facility should offer genetic counseling services to help you understand the results and their implications.
  4. Advanced Technology: Choose a facility that uses the latest sequencing technology for accurate and reliable results.
  5. Patient Support Services: Consider facilities that provide ongoing support and resources for managing FMF and related conditions.

Pre Test Information

Familial Mediterranean Fever: MEFV full gene analysis can be done with a doctor’s prescription. Please note that the prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.

Test Details

Familial Mediterranean Fever (FMF) is an inherited autoinflammatory disorder that primarily affects people of Mediterranean origin. It is caused by mutations in the MEFV gene, which encodes for a protein called pyrin. Pyrin is involved in regulating the body’s inflammatory response.

There are more than 300 known mutations in the MEFV gene, with the most common mutations found in exons 2, 3, 5, and 10. Genetic testing for FMF typically involves sequencing these exons to identify any mutations. However, a full gene analysis of MEFV involves sequencing the entire gene, including all exons and introns. This comprehensive analysis can identify rare mutations that may not be detected by sequencing only the common exons.

A full gene analysis can also help to identify genetic variants that may contribute to disease severity or treatment response. Various genetic testing methods, such as Sanger sequencing, next-generation sequencing, and targeted gene panels, can be used to perform a full gene analysis of MEFV.

The results of genetic testing can help to confirm a diagnosis of FMF, guide treatment decisions, and provide valuable information for genetic counseling of affected individuals and their families.

Conclusion

Familial Mediterranean Fever is a complex condition requiring accurate diagnosis and personalized treatment plans. MEFV full gene analysis offers a powerful tool for achieving these goals, providing critical insights into the genetic basis of FMF. For individuals in the UAE, understanding the importance of MEFV full gene analysis and choosing the right facility can significantly impact the management and outcome of this condition. By leveraging advanced genetic testing, patients can receive more effective treatments, gain valuable information for family planning, and ultimately improve their quality of life.

Test Name: Familial Mediterranean Fever MEFV Full Gene Analysis Test

Components: EDTA Vacutainer (3 ml)

Price: 7200.0 AED

Sample Condition: Peripheral blood

Report Delivery: 4-6 weeks

Method: NGS (Next-Generation Sequencing)

Test Type: Genetics

Doctor: General Physician

Test Department: DNA Labs UAE

Test NameFamilial Mediterranean Fever MEFV full gene Analysis Test
ComponentsEDTA Vacutainer (3 ml)
Price 7200.0 AED
Sample ConditionPeripheral blood
Report Delivery4-6 weeks
MethodNGS
Test typeGenetics
DoctorGeneral Physician
Test Department:
Pre Test InformationFamilial Mediterranean Fever: MEFV full gene Analysis can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.
Test DetailsFamilial Mediterranean Fever (FMF) is an inherited autoinflammatory disorder that primarily affects people of Mediterranean origin. It is caused by mutations in the MEFV gene, which encodes for a protein called pyrin. Pyrin is involved in regulating the body’s inflammatory response.There are more than 300 known mutations in the MEFV gene, and the most common mutations are found in exons 2, 3, 5, and 10. Genetic testing for FMF typically involves sequencing these exons to identify any mutations.

However, a full gene analysis of MEFV involves sequencing the entire gene, including all exons and introns. This can identify rare mutations that may not be detected by sequencing only the common exons. A full gene analysis can also help to identify genetic variants that may contribute to disease severity or treatment response.

A full gene analysis of MEFV can be performed using a variety of genetic testing methods, including Sanger sequencing, next-generation sequencing, and targeted gene panels. The results of genetic testing can help to confirm a diagnosis of FMF, guide treatment decisions, and inform genetic counseling for affected individuals and their families.