Test Price
2,800 AED✅ Home Collection Available
EN2 Gene (Autism Spectrum Disorder) Genetic Test in UAE | 2,800 AED | DNA Labs UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Genetic Counselling & Result Interpretation by a Consultant Medical Geneticist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
This clinically actionable genetic test identifies pathogenic variants in the EN2 gene associated with autism spectrum disorder risk, enabling personalised early intervention strategies and informed family planning.
Test Overview & Methodology
The EN2 gene test utilises next-generation sequencing (NGS) to analyse the complete coding region of the EN2 gene, detecting single nucleotide variants, small insertions and deletions, and copy number changes. This comprehensive approach provides a robust genetic foundation for understanding ASD susceptibility, particularly when a family history of neurodevelopmental disorders is present.
| Feature | Our Test (NGS) | Closest Alternative (Targeted Panel) |
|---|---|---|
| Precision | >99.9% analytical sensitivity | Limited to pre-selected hotspots |
| Methodology | Full gene NGS (Illumina® platform) | PCR-based, may miss novel variants |
| Turnaround | 21 working days | 10–14 working days |
| Clinical Utility | Comprehensive variant detection + genetic counselling | Basic report without counselling |
Physician Insight & Safety Protocols
"As a Consultant Medical Genetics, I recognise the emotional and clinical significance of identifying a genetic contributor to autism spectrum disorder. The EN2 gene test provides a critical piece of the diagnostic puzzle, yet it must be integrated with comprehensive developmental assessments and multidisciplinary evaluations. I strongly advise against making any treatment or therapeutic decisions based solely on genetic findings without consulting a qualified specialist."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication & Clinical Advisory
⚠ Important Clinical Warning
Do not discontinue, alter, or initiate any prescribed medication or therapy without direct consultation with your treating physician. Genetic results should complement, not replace, professional medical judgement.
All sample collection and testing protocols strictly adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring patient safety and informed consent at every stage.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion: Individuals unable to provide informed consent (minors require parental or legal guardian consent in accordance with UAE Federal Law).
- Exclusion: Patients currently undergoing chemotherapy or those who have received a blood transfusion within the past 72 hours (may affect DNA yield and quality).
- Red Flag: Severe acute illness or uncontrolled epilepsy – postpone sample collection and contact your physician immediately.
- Red Flag: If the patient exhibits harmful behaviours toward self or others, seek urgent psychiatric care before proceeding with genetic testing.
Patient FAQ & Clinical Guidance
1. What is the EN2 gene test and what does it detect?
The EN2 gene test employs next-generation sequencing to identify pathogenic variants within the EN2 gene that are linked to an increased risk of autism spectrum disorder. It analyses the entire coding region, detecting single nucleotide variants, small insertions and deletions, and copy number changes. This test is particularly valuable when a strong family history of neurodevelopmental disorders exists or when clinical presentation suggests a genetic aetiology.
2. How is the sample collected and what preparation is needed?
Sample collection is straightforward and requires either a whole blood draw in EDTA tubes, a dried blood spot on an FTA card, or a buccal swab. Our team will arrange a VIP home visit between 8 AM and 11 PM via temperature-controlled cold-chain logistics. No fasting is necessary. A mandatory pre-test genetic counselling session is conducted to construct a three-generation pedigree and ensure you fully understand the scope, limitations, and possible outcomes of the test.
3. How is the result interpreted and what follow-up counselling is provided?
Results are classified according to American College of Medical Genetics and Genomics (ACMG) standards as pathogenic, likely pathogenic, variant of uncertain significance, likely benign, or benign. After the report is issued, you will receive a telephonic genetic counselling session with a consultant medical geneticist. This session explains the clinical implications of the identified variant, recommends next steps such as comprehensive developmental assessment or family planning, and provides a written summary in English or Arabic.
4. What is the turnaround time and how will I receive my results?
The standard turnaround time is 21 working days from the date the sample is received at our ISO-accredited laboratory. Results are delivered via a secure, encrypted digital portal and a printed hard copy is provided upon request. Your referring physician will also receive a clinical summary to facilitate integrated care planning.
UAE Regulatory & Data Privacy Adherence
- Full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) for all genetic and personal data processing.
- Strict adherence to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields for secure health data exchange.
- All data encrypted and stored on UAE-based servers in alignment with Dubai Health Authority (DHA) and Ministry of Health and Prevention (MOHAP) standards.
- ISO 9001:2015 Certified Facility – Certificate No. INT/EGQ/2509DA/3139.
Clinical & Logistical Metadata
| Test Name | EN2 Gene (Autism Spectrum Disorder) Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 21 Working Days |
| Sample Type / Matrix | Whole Blood (EDTA), Dried Blood Spot (FTA Card), or Buccal Swab |
| Methodology Used | Next-Generation Sequencing (NGS) – Full Gene Sequencing (Illumina® Platform) |
| ICD-10-CM Code | F84.0 |
| LOINC Code | 55233-1 |
| DHA Facility License & Laboratory Address | DHA Facility License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians