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Cytochrome P450 2D6 Genotyping CYP2D6 – Alleles Test Cost

Original price was: 1,800 د.إ.Current price is: 1,350 د.إ.

-25%

Cytochrome P450 2D6 (CYP2D6) genotyping is a genetic test performed to identify variations in the CYP2D6 gene, which can influence an individual’s ability to metabolize certain medications. The CYP2D6 enzyme plays a crucial role in the metabolism of a wide range of drugs, including antidepressants, antipsychotics, beta-blockers, and opioids. Variations or alleles in the CYP2D6 gene can lead to differences in drug metabolism rates, affecting drug efficacy and risk of side effects.

The CYP2D6 alleles test is aimed at determining an individual’s genotype to predict their metabolizer status – whether they are poor, intermediate, extensive, or ultrarapid metabolizers. This information is valuable for healthcare providers to tailor medication types and dosages for optimal therapeutic outcomes and minimized adverse effects.

In the United Arab Emirates, DNA Labs UAE offers the CYP2D6 genotyping test at a cost of 1350 AED. The test involves a simple and non-invasive sample collection process, typically a cheek swab or a blood sample. Once the sample is analyzed, the results can help guide personalized medicine approaches, ensuring that patients receive the most appropriate and effective medication based on their genetic makeup.

Description

Cytochrome P450 2D6 Genotyping CYP2D6 – Alleles Test

Test Name: Cytochrome P450 2D6 Genotyping CYP2D6 – Alleles Test

Components: EDTA Vacutainer (2ml)

Price: 1350.0 AED

Sample Condition: Peripheral blood

Report Delivery: 10-12 days

Method: Sanger Sequencing

Test type: Genetics

Doctor: Gynecologist

Test Department:

Pre Test Information: Cytochrome P450 2D6 Genotyping (CYP2D6 – Alleles) can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.

Test Details: Cytochrome P450 2D6 (CYP2D6) is an enzyme responsible for metabolizing a wide range of drugs in the body. Genetic variations in the CYP2D6 gene can lead to differences in enzyme activity, which can affect the way individuals metabolize certain medications.

There are several known genetic variations, or alleles, of the CYP2D6 gene. These alleles can be categorized into different phenotypes based on their activity levels. The most common phenotypes include:

Poor metabolizers (PM): These individuals have two non-functional alleles, resulting in little to no enzyme activity. Poor metabolizers may experience increased drug levels and potential side effects when taking medications metabolized by CYP2D6.
Intermediate metabolizers (IM): Individuals with one non-functional allele and one allele with reduced activity fall into this category. Intermediate metabolizers may have slower metabolism of CYP2D6 substrates compared to normal metabolizers.
Normal metabolizers (NM): These individuals have two functional alleles, resulting in normal enzyme activity. Normal metabolizers are expected to have typical drug metabolism for CYP2D6 substrates.
Ultrarapid metabolizers (UM): Individuals with multiple copies of functional alleles may fall into this category. Ultrarapid metabolizers have increased enzyme activity, leading to faster drug metabolism. This can result in reduced drug efficacy for some medications.

Genotyping tests can determine an individual’s CYP2D6 genotype by identifying specific alleles present in their DNA. This information can help healthcare providers personalize medication dosing and selection, especially for drugs that are metabolized by CYP2D6.

Test Name	Cytochrome P450 2D6 Genotyping CYP2D6 – Alleles Test
Components	EDTA Vacutainer (2ml)
Price	1350.0 AED
Sample Condition	Peripheral blood
Report Delivery	10-12 days
Method	Sanger Sequencing
Test type	Genetics
Doctor	Gynecologist
Test Department:
Pre Test Information	Cytochrome P450 2D6 Genotyping (CYP2D6 – Alleles) can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.
Test Details	Cytochrome P450 2D6 (CYP2D6) is an enzyme responsible for metabolizing a wide range of drugs in the body. Genetic variations in the CYP2D6 gene can lead to differences in enzyme activity, which can affect the way individuals metabolize certain medications. There are several known genetic variations, or alleles, of the CYP2D6 gene. These alleles can be categorized into different phenotypes based on their activity levels. The most common phenotypes include: 1. Poor metabolizers (PM): These individuals have two non-functional alleles, resulting in little to no enzyme activity. Poor metabolizers may experience increased drug levels and potential side effects when taking medications metabolized by CYP2D6. 2. Intermediate metabolizers (IM): Individuals with one non-functional allele and one allele with reduced activity fall into this category. Intermediate metabolizers may have slower metabolism of CYP2D6 substrates compared to normal metabolizers. 3. Normal metabolizers (NM): These individuals have two functional alleles, resulting in normal enzyme activity. Normal metabolizers are expected to have typical drug metabolism for CYP2D6 substrates. 4. Ultrarapid metabolizers (UM): Individuals with multiple copies of functional alleles may fall into this category. Ultrarapid metabolizers have increased enzyme activity, leading to faster drug metabolism. This can result in reduced drug efficacy for some medications. Genotyping tests can determine an individual’s CYP2D6 genotype by identifying specific alleles present in their DNA. This information can help healthcare providers personalize medication dosing and selection, especially for drugs that are metabolized by CYP2D6.