Cytochrome P450 2C19 Genotyping CYP2C19 Clopidogrel Resistance 23410 Test sale cost 1200 AED
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Cytochrome P450 2C19 Genotyping CYP2C19 Clopidogrel Resistance 23410 Test Cost

Original price was: 1,600 د.إ.Current price is: 1,200 د.إ.

-25%

The Cytochrome P450 2C19 Genotyping (CYP2C19) Clopidogrel Resistance 23410 Test is a specialized diagnostic examination available at DNA Labs UAE, designed to identify genetic variations in the CYP2C19 gene. These genetic differences can significantly affect how an individual metabolizes certain medications, including clopidogrel, a commonly prescribed antiplatelet drug used to prevent blood clots. The test’s primary aim is to detect specific genetic markers associated with reduced enzyme activity, which can lead to clopidogrel resistance, potentially increasing the risk of cardiovascular events in patients.

Understanding an individual’s CYP2C19 genotype is crucial for healthcare providers to tailor medication choices and dosages for optimal efficacy and safety, particularly in patients undergoing treatments for conditions like coronary artery disease, stroke, and other thrombotic disorders. The test, priced at 1200 AED, involves a simple genetic analysis, usually through a blood sample, and provides valuable insights that can guide personalized treatment plans, enhancing patient outcomes and minimizing adverse drug reactions. DNA Labs UAE, a leading provider of genetic testing services, offers this advanced diagnostic tool as part of its comprehensive portfolio to support personalized medicine and improve patient care.

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Cytochrome P450 2C19 Genotyping CYP2C19 Clopidogrel resistance *2*3*4*10 Test

Test Name: Cytochrome P450 2C19 Genotyping CYP2C19 Clopidogrel resistance *2*3*4*10 Test

Components: EDTA Vacutainer (2ml)

Price: 1200.0 AED

Sample Condition: Peripheral blood

Report Delivery: 7 days

Method: Sanger Sequencing

Test Type: Genetics

Doctor: Gynecologist

Test Department: Pre Test Information

Cytochrome P450 2C19 Genotyping (CYP2C19) Clopidogrel resistance (*2,*3,*4,*10) can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.

Test Details

Cytochrome P450 2C19 (CYP2C19) is an enzyme involved in the metabolism of various drugs, including clopidogrel. Clopidogrel is an antiplatelet medication commonly used to prevent blood clots in patients with cardiovascular diseases. However, some individuals may have a genetic variation in the CYP2C19 gene that affects the activity of the enzyme. This genetic variation can result in reduced or absent CYP2C19 enzyme function, leading to decreased metabolism of clopidogrel and reduced effectiveness of the medication. This is known as clopidogrel resistance.

There are several genetic variants of CYP2C19 that have been identified as being associated with clopidogrel resistance. These include the *2, *3, *4, and *10 alleles. These alleles are responsible for producing non-functional or reduced-function CYP2C19 enzymes. Individuals who carry one or two copies of these alleles are at an increased risk of clopidogrel resistance and may not receive the full therapeutic benefit of the medication.

Therefore, genotyping for CYP2C19 variants is recommended in certain clinical situations, such as prior to initiating clopidogrel therapy or in patients who experience recurrent cardiovascular events despite being on clopidogrel. By identifying individuals with these genetic variants, alternative antiplatelet medications or higher doses of clopidogrel can be considered to overcome the reduced effectiveness of the drug.

Test Name Cytochrome P450 2C19 Genotyping CYP2C19 Clopidogrel resistance *2*3*4*10 Test
Components EDTA Vacutainer (2ml)
Price 1200.0 AED
Sample Condition Peripheral blood
Report Delivery 7 days
Method Sanger Sequencing
Test type Genetics
Doctor Gynecologist
Test Department:
Pre Test Information Cytochrome P450 2C19 Genotyping (CYP2C19) Clopidogrel resistance (*2,*3,*4,*10) can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.
Test Details

Cytochrome P450 2C19 (CYP2C19) is an enzyme involved in the metabolism of various drugs, including clopidogrel. Clopidogrel is an antiplatelet medication commonly used to prevent blood clots in patients with cardiovascular diseases.

However, some individuals may have a genetic variation in the CYP2C19 gene that affects the activity of the enzyme. This genetic variation can result in reduced or absent CYP2C19 enzyme function, leading to decreased metabolism of clopidogrel and reduced effectiveness of the medication. This is known as clopidogrel resistance.

There are several genetic variants of CYP2C19 that have been identified as being associated with clopidogrel resistance. These include the *2, *3, *4, and *10 alleles. These alleles are responsible for producing non-functional or reduced-function CYP2C19 enzymes.

Individuals who carry one or two copies of these alleles are at an increased risk of clopidogrel resistance and may not receive the full therapeutic benefit of the medication. Therefore, genotyping for CYP2C19 variants is recommended in certain clinical situations, such as prior to initiating clopidogrel therapy or in patients who experience recurrent cardiovascular events despite being on clopidogrel.

By identifying individuals with these genetic variants, alternative antiplatelet medications or higher doses of clopidogrel can be considered to overcome the reduced effectiveness of the drug.

SKU: TEST-5353