CALCITONIN STIMULATION BY CALCIUM – PENTAGASTRIN Test
Components
For suspected Medullary Thyroid Carcinoma
Price: 2380.0 AED
Sample Condition
2 mL (0.5 mL min.) serum from 1 Red Top (No Additive) tube for each timed specimen. Do not use SST gel barrier tubes. All containers must be clearly marked with time drawn and submitted with 1 test request form. Draw overnight fasting baseline specimen. With patient supine, administer Calcium Gluconate IV 2 mg/kg body weight over 1 min. followed by Pentagastrin IV bolus 0.5 ug/kg body weight over 5 sec. Draw additional specimens at 1, 2, 5 and 10 min. Ship frozen. DO NOT THAW.
Report Delivery
SampleMon / Thu by 4 pm; Report Same day
Method
Chemiluminescent Immunoassay
Test Type
Cancer
Doctor
Oncologist
Test Department
Pre Test Information
Overnight fasting is mandatory.
Test Details
The calcitonin stimulation test, also known as the pentagastrin test, is a medical procedure used to assess the functioning of the thyroid gland. It involves the administration of pentagastrin, a synthetic hormone that stimulates the release of calcitonin from the thyroid gland.
During the test, the patient is given an intravenous injection of pentagastrin. This hormone acts on the C cells of the thyroid gland, which are responsible for producing calcitonin. As a response to pentagastrin, the C cells release calcitonin into the bloodstream.
Calcitonin is a hormone that plays a crucial role in regulating calcium levels in the body. It acts to decrease the levels of calcium in the blood by inhibiting its release from the bones and increasing its excretion by the kidneys.
By measuring the levels of calcitonin in the blood before and after the pentagastrin injection, doctors can evaluate the functioning of the thyroid gland. If the levels of calcitonin increase significantly after the injection, it indicates that the thyroid gland is functioning normally. However, if there is a minimal or no increase in calcitonin levels, it may indicate an abnormality in the thyroid gland, such as a tumor.
The calcitonin stimulation test is primarily used in the diagnosis and monitoring of medullary thyroid cancer (MTC). MTC is a rare form of thyroid cancer that arises from the C cells of the thyroid gland. High levels of calcitonin are characteristic of MTC, and the test helps in confirming the diagnosis and monitoring the effectiveness of treatment.
It is important to note that the calcitonin stimulation test should only be performed by qualified healthcare professionals in a controlled medical setting. The procedure may have some side effects, including nausea, flushing, and changes in blood pressure. Therefore, it is essential to discuss the risks and benefits of the test with a healthcare provider before undergoing the procedure.
| Test Name | CALCITONIN STIMULATION BY CALCIUM – PENTAGASTRIN Test |
|---|---|
| Components | For suspected Medullary Thyroid Carcinoma |
| Price | 2380.0 AED |
| Sample Condition | 2 mL (0.5 mL min.) serum from 1 Red Top (No Additive) tube foreach timed specimen.Do not use SST gel barrier tubes. All containersmust be clearly marked with time drawn and submitted with 1 test request form. Draw overnight fasting baseline specimen. With patient supine, administer Calcium Gluconate IV 2 mg\/ kg body weight over 1 min. followed by Pentagastrin IV bolus 0.5 ug\/kg body weight over 5 sec. Draw additional specimens at 1, 2, 5 and 10 min. Ship frozen. DO NOT THAW. |
| Report Delivery | SampleMon / Thu by 4 pm; Report Same day |
| Method | Chemiluminescent Immunoassay |
| Test type | Cancer |
| Doctor | Oncologist |
| Test Department: | |
| Pre Test Information | Overnight fasting is mandatory. |
| Test Details | The calcitonin stimulation test, also known as the pentagastrin test, is a medical procedure used to assess the functioning of the thyroid gland. It involves the administration of pentagastrin, a synthetic hormone that stimulates the release of calcitonin from the thyroid gland. During the test, the patient is given an intravenous injection of pentagastrin. This hormone acts on the C cells of the thyroid gland, which are responsible for producing calcitonin. As a response to pentagastrin, the C cells release calcitonin into the bloodstream. Calcitonin is a hormone that plays a crucial role in regulating calcium levels in the body. It acts to decrease the levels of calcium in the blood by inhibiting its release from the bones and increasing its excretion by the kidneys. By measuring the levels of calcitonin in the blood before and after the pentagastrin injection, doctors can evaluate the functioning of the thyroid gland. If the levels of calcitonin increase significantly after the injection, it indicates that the thyroid gland is functioning normally. However, if there is a minimal or no increase in calcitonin levels, it may indicate an abnormality in the thyroid gland, such as a tumor. The calcitonin stimulation test is primarily used in the diagnosis and monitoring of medullary thyroid cancer (MTC). MTC is a rare form of thyroid cancer that arises from the C cells of the thyroid gland. High levels of calcitonin are characteristic of MTC, and the test helps in confirming the diagnosis and monitoring the effectiveness of treatment. It is important to note that the calcitonin stimulation test should only be performed by qualified healthcare professionals in a controlled medical setting. The procedure may have some side effects, including nausea, flushing, and changes in blood pressure. Therefore, it is essential to discuss the risks and benefits of the test with a healthcare provider before undergoing the procedure. |
