BCR-ABL1 Quantification by DD PCR Test

Cost: AED 1800.0

Test Details:

BCR-ABL1 quantification by droplet digital PCR (ddPCR) is a method used to measure the amount of the BCR-ABL1 fusion gene in a sample. This fusion gene is commonly found in patients with chronic myeloid leukemia (CML) and is used as a biomarker for disease progression and response to treatment.

The ddPCR technique involves partitioning the sample into thousands of individual droplets, each containing a single DNA molecule. The droplets are then subjected to PCR amplification, with fluorescent probes targeting the BCR-ABL1 fusion gene and a reference gene.

After PCR amplification, the droplets are analyzed using a droplet reader, which counts the number of positive and negative droplets for each target. The ratio of positive droplets for the BCR-ABL1 fusion gene to the reference gene can be used to determine the relative abundance of the fusion gene in the sample.

This quantification is typically reported as a percentage or as a standardized international scale (IS) value. BCR-ABL1 quantification by ddPCR is a highly sensitive and precise method, capable of detecting and quantifying low levels of the fusion gene.

It is commonly used in clinical laboratories for monitoring CML patients during treatment, as well as for detecting minimal residual disease (MRD) after treatment. Overall, BCR-ABL1 quantification by ddPCR is an important tool in the management of CML patients, allowing for accurate monitoring of disease progression and response to therapy.

Test Components:

• Streck Tube

Price:

AED 1800.0

Sample Condition:

Peripheral Blood

Report Delivery:

2-3 days

Method:

Droplet Digital PCR

Test Type:

Genetics

Doctor:

Oncology

Test Department:

Pre Test Information

BCR-ABL1 Quantification by DD PCR can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.