APOC2 Gene Apolipoprotein C-II deficiency Genetic Test
Components:
- Price: 4400.0 AED
Sample Condition:
Blood or Extracted DNA or One drop Blood on FTA Card
Report Delivery:
3 to 4 Weeks
Method:
NGS Technology
Test Type:
Metabolic Disorders
Doctor:
General Physician
Test Department:
Genetics
Pre Test Information:
Clinical History of Patient who is going for APOC2 Gene Apolipoprotein C-II deficiency NGS Genetic DNA Test
A Genetic Counselling session to draw a pedigree chart of family members affected with Apolipoprotein C-II deficiency
Test Details:
The APOC2 gene is responsible for producing apolipoprotein C-II, a protein that plays a crucial role in the metabolism of lipoproteins, particularly triglyceride-rich particles called chylomicrons and very low-density lipoproteins (VLDLs). Apolipoprotein C-II activates the enzyme lipoprotein lipase (LPL), which breaks down triglycerides in these lipoproteins, allowing their uptake by tissues for energy production.
Apolipoprotein C-II deficiency is a rare genetic disorder characterized by low levels or absence of apolipoprotein C-II. This deficiency impairs the function of LPL, leading to elevated levels of triglycerides in the blood, a condition known as hypertriglyceridemia. Individuals with APOC2 deficiency are at an increased risk of developing recurrent episodes of pancreatitis, a painful inflammation of the pancreas.
NGS (Next-Generation Sequencing) genetic testing is a type of genetic test that uses advanced sequencing technologies to analyze multiple genes simultaneously. In the context of APOC2 deficiency, NGS genetic testing can identify mutations or variations in the APOC2 gene that may be responsible for the condition. This testing method allows for a comprehensive analysis of the entire gene, enabling the detection of both common and rare genetic variants associated with APOC2 deficiency.
NGS genetic testing for APOC2 deficiency can provide valuable information for diagnosis, genetic counseling, and management of individuals suspected to have or at risk for this condition. It can help confirm the diagnosis, identify carriers of the gene mutation, and guide treatment decisions, such as dietary modifications, lifestyle changes, and potential drug interventions to manage hypertriglyceridemia and prevent pancreatitis episodes.
| Test Name | APOC2 Gene Apolipoprotein C-II deficiency Genetic Test |
|---|---|
| Components | |
| Price | 4400.0 AED |
| Sample Condition | Blood or Extracted DNA or One drop Blood on FTA Card |
| Report Delivery | 3 to 4 Weeks |
| Method | NGS Technology |
| Test type | Metabolic Disorders |
| Doctor | General Physician |
| Test Department: | Genetics |
| Pre Test Information | Clinical History of Patient who is going for APOC2 Gene Apolipoprotein C-II deficiency NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Apolipoprotein C-II deficiency |
| Test Details |
The APOC2 gene is responsible for producing apolipoprotein C-II, a protein that plays a crucial role in the metabolism of lipoproteins, particularly triglyceride-rich particles called chylomicrons and very low-density lipoproteins (VLDLs). Apolipoprotein C-II activates the enzyme lipoprotein lipase (LPL), which breaks down triglycerides in these lipoproteins, allowing their uptake by tissues for energy production. Apolipoprotein C-II deficiency is a rare genetic disorder characterized by low levels or absence of apolipoprotein C-II. This deficiency impairs the function of LPL, leading to elevated levels of triglycerides in the blood, a condition known as hypertriglyceridemia. Individuals with APOC2 deficiency are at an increased risk of developing recurrent episodes of pancreatitis, a painful inflammation of the pancreas. NGS (Next-Generation Sequencing) genetic testing is a type of genetic test that uses advanced sequencing technologies to analyze multiple genes simultaneously. In the context of APOC2 deficiency, NGS genetic testing can identify mutations or variations in the APOC2 gene that may be responsible for the condition. This testing method allows for a comprehensive analysis of the entire gene, enabling the detection of both common and rare genetic variants associated with APOC2 deficiency. NGS genetic testing for APOC2 deficiency can provide valuable information for diagnosis, genetic counseling, and management of individuals suspected to have or at risk for this condition. It can help confirm the diagnosis, identify carriers of the gene mutation, and guide treatment decisions, such as dietary modifications, lifestyle changes, and potential drug interventions to manage hypertriglyceridemia and prevent pancreatitis episodes. |
