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AML Panel Cytogenetics and FISH AMLETO Inv16 PML-RARA MLL Test

Original price was: 4,940 د.إ.Current price is: 4,450 د.إ.

-10%

The “AML Panel Cytogenetics and FISH AMLETO Inv16 PML-RARA MLL Test” is a comprehensive diagnostic assessment designed to identify specific genetic abnormalities associated with Acute Myeloid Leukemia (AML). This test is pivotal in the diagnosis and management of AML, a type of cancer that affects the blood and bone marrow, characterized by the rapid growth of abnormal white blood cells. The panel includes cytogenetic analysis and Fluorescence In Situ Hybridization (FISH) to detect chromosomal alterations such as Inv16, PML-RARA, and MLL rearrangements, which are crucial for determining prognosis, guiding treatment decisions, and monitoring response to therapy.

Performed at DNA Labs UAE, a state-of-the-art facility known for its advanced diagnostic services, this test is priced at 4450 AED. The laboratory utilizes cutting-edge technology and adheres to stringent quality control measures to ensure accurate and reliable results. By identifying specific genetic mutations and chromosomal changes, the AML Panel Cytogenetics and FISH test provides essential information that helps clinicians tailor treatment strategies to the individual needs of their patients, ultimately aiming to improve outcomes in those affected by Acute Myeloid Leukemia.

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AML PANEL Cytogenetics and FISH AMLETO inv16 PMLRARA MLL Test

Test Name: AML PANEL Cytogenetics and FISH AMLETO inv16 PMLRARA MLL Test

Components: Sodium Heparin Vacutainer (2ml)

Price: 4450.0 AED

Sample Condition: Bone marrow / Peripheral blood (Transport immediately)

Report Delivery: 5-7 days

Method: Cell Culture + FISH

Test type: Genetics

Doctor: Gynecologist

Test Department:

Pre Test Information: AML PANEL (Cytogenetics + FISH AML/ETO, inv(16), PML/RARA, MLL) can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.

Test Details

The AML panel typically includes cytogenetic analysis and fluorescence in situ hybridization (FISH) for specific genetic abnormalities associated with acute myeloid leukemia (AML). The panel includes testing for the following genetic abnormalities:

  1. AML/ETO: This FISH test detects the t(8;21) translocation, which results in the fusion of the AML1 and ETO genes. This translocation is associated with a subtype of AML called AML with t(8;21) (also known as AML-M2).
  2. inv(16): This FISH test detects the inversion of chromosome 16, which results in the formation of the CBFB-MYH11 fusion gene. This abnormality is associated with a subtype of AML called AML with inv(16) (also known as AML-M4Eo).
  3. PML/RARA: This FISH test detects the t(15;17) translocation, which results in the fusion of the PML and RARA genes. This translocation is associated with a subtype of AML called acute promyelocytic leukemia (APL) or AML-M3.
  4. MLL: This FISH test detects rearrangements involving the MLL gene (also known as KMT2A), which can occur through various translocations, insertions, or inversions. MLL rearrangements are associated with a subset of AML cases, particularly in infants and young children.

By analyzing these genetic abnormalities, the AML panel helps in the diagnosis, classification, and prognosis of AML patients. The results of the panel can guide treatment decisions, as some genetic abnormalities may have specific targeted therapies available.

Test Name AML PANEL Cytogenetics and FISH AMLETO inv16 PMLRARA MLL Test
Components Sodium Heparin Vacutainer (2ml)
Price 4450.0 AED
Sample Condition Bone marrow \/ Peripheral blood (Transport immediately)
Report Delivery 5-7 days
Method Cell Culture + FISH
Test type Genetics
Doctor Gynecologist
Test Department:
Pre Test Information AML PANEL (Cytogenetics + FISH AML/ETO, inv(16), PML/RARA, MLL]) can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.
Test Details

The AML panel typically includes cytogenetic analysis and fluorescence in situ hybridization (FISH) for specific genetic abnormalities associated with acute myeloid leukemia (AML). The panel includes testing for the following genetic abnormalities:

1. AML/ETO: This FISH test detects the t(8;21) translocation, which results in the fusion of the AML1 and ETO genes. This translocation is associated with a subtype of AML called AML with t(8;21) (also known as AML-M2).

2. inv(16): This FISH test detects the inversion of chromosome 16, which results in the formation of the CBFB-MYH11 fusion gene. This abnormality is associated with a subtype of AML called AML with inv(16) (also known as AML-M4Eo).

3. PML/RARA: This FISH test detects the t(15;17) translocation, which results in the fusion of the PML and RARA genes. This translocation is associated with a subtype of AML called acute promyelocytic leukemia (APL) or AML-M3.

4. MLL: This FISH test detects rearrangements involving the MLL gene (also known as KMT2A), which can occur through various translocations, insertions, or inversions. MLL rearrangements are associated with a subset of AML cases, particularly in infants and young children.

By analyzing these genetic abnormalities, the AML panel helps in the diagnosis, classification, and prognosis of AML patients. The results of the panel can guide treatment decisions, as some genetic abnormalities may have specific targeted therapies available.