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AML FISH PANEL FISH AMLETO inv16 PMLRARA MLL Test

Name: AML FISH PANEL FISH AMLETO inv16 PMLRARA MLL Test
SKU: TEST-4716
Price: 2970 AED
Availability: InStock

Original price was: 3,960 د.إ.Current price is: 2,970 د.إ.

-25%

The AML FISH Panel is a specialized diagnostic test used in the detection of genetic abnormalities associated with Acute Myeloid Leukemia (AML), a type of cancer that affects the blood and bone marrow. This panel specifically targets the identification of chromosomal alterations such as inv16, PML-RARA, and MLL rearrangements, which are crucial for the diagnosis, prognosis, and treatment planning of AML.

The inv(16) mutation involves the inversion of chromosome 16, which is commonly associated with a subtype of AML known as M4Eo. The PML-RARA fusion gene results from the translocation between chromosomes 15 and 17, characteristic of Acute Promyelocytic Leukemia (APL), a subtype of AML. The MLL gene rearrangement involves various translocations affecting the MLL gene on chromosome 11q23, which are found in different types of leukemia, including AML.

Performed at DNA Labs UAE, the AML FISH Panel employs Fluorescence In Situ Hybridization (FISH) technology, a powerful technique that allows for the visualization of specific genetic changes in the chromosomes of individual cells. This test is particularly valuable for patients suspected of having AML, as it helps in confirming the diagnosis, determining the specific subtype of leukemia, and guiding treatment decisions based on the genetic profile of the disease.

The cost of the AML FISH Panel test at DNA Labs UAE is 2970 AED. Given the complexity of the test and the critical information it provides, it represents a significant step towards personalized medicine in the treatment of AML, offering patients targeted therapy options based on their specific genetic abnormalities.

Description

AML FISH PANEL FISH AMLETO inv16 PMLRARA MLL Test

Test Name: AML FISH PANEL FISH AMLETO inv16 PMLRARA MLL Test

Components: Sodium Heparin Vacutainer (2ml)

Price: 2970.0 AED

Sample Condition: Bone marrow / Peripheral blood (Transport immediately)

Report Delivery: 5-7 days

Method: FISH

Test type: Genetics

Doctor: Oncology

Test Department: Pre Test Information

Pre Test Information: AML FISH PANEL (FISH AML/ETO, inv(16), PML/RARA, MLL) can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.

Test Details: The AML FISH panel is a genetic test used to detect specific chromosomal abnormalities associated with acute myeloid leukemia (AML). This panel includes four specific genetic abnormalities:

AML/ETO: This test detects the presence of a fusion gene between the AML1 (also known as RUNX1) gene and the ETO (also known as RUNX1T1) gene. This fusion gene is found in a subset of AML cases and is associated with a favorable prognosis.
inv(16): This test detects the presence of an inversion of chromosome 16. This chromosomal abnormality is associated with the fusion gene CBFB-MYH11, which is found in a subtype of AML known as acute myelomonocytic leukemia with abnormal eosinophils (AML-M4Eo).
PML/RARA: This test detects the presence of a fusion gene between the PML (promyelocytic leukemia) gene and the RARA (retinoic acid receptor alpha) gene. This fusion gene is characteristic of acute promyelocytic leukemia (APL), a subtype of AML that is highly sensitive to treatment with all-trans retinoic acid (ATRA).
MLL: This test detects rearrangements involving the MLL (mixed lineage leukemia) gene. MLL rearrangements are associated with a poor prognosis in AML, particularly in infants and young children.

The AML FISH panel is used to aid in the diagnosis and risk stratification of AML patients. It provides important information about the specific genetic abnormalities present in the leukemia cells, which can help guide treatment decisions and predict patient outcomes.

Test Name	AML FISH PANEL FISH AMLETO inv16 PMLRARA MLL Test
Components	Sodium Heparin Vacutainer (2ml)
Price	2970.0 AED
Sample Condition	Bone marrow \/ Peripheral blood (Transport immediately)
Report Delivery	5-7 days
Method	FISH
Test type	Genetics
Doctor	Oncology
Test Department:
Pre Test Information	AML FISH PANEL (FISH AML/ETO, inv(16), PML/RARA, MLL]) can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.
Test Details	The AML FISH panel is a genetic test used to detect specific chromosomal abnormalities associated with acute myeloid leukemia (AML). This panel includes four specific genetic abnormalities: 1. AML/ETO: This test detects the presence of a fusion gene between the AML1 (also known as RUNX1) gene and the ETO (also known as RUNX1T1) gene. This fusion gene is found in a subset of AML cases and is associated with a favorable prognosis. 2. inv(16): This test detects the presence of an inversion of chromosome 16. This chromosomal abnormality is associated with the fusion gene CBFB-MYH11, which is found in a subtype of AML known as acute myelomonocytic leukemia with abnormal eosinophils (AML-M4Eo). 3. PML/RARA: This test detects the presence of a fusion gene between the PML (promyelocytic leukemia) gene and the RARA (retinoic acid receptor alpha) gene. This fusion gene is characteristic of acute promyelocytic leukemia (APL), a subtype of AML that is highly sensitive to treatment with all-trans retinoic acid (ATRA). 4. MLL: This test detects rearrangements involving the MLL (mixed lineage leukemia) gene. MLL rearrangements are associated with a poor prognosis in AML, particularly in infants and young children. The AML FISH panel is used to aid in the diagnosis and risk stratification of AML patients. It provides important information about the specific genetic abnormalities present in the leukemia cells, which can help guide treatment decisions and predict patient outcomes.