ABL Gene Load Test Cost AED:900.0
Are you looking for information on the ABL Gene Load Test? Look no further! DNA Labs UAE offers the ABL Gene Load Test at a cost of AED 900.0. Read on to learn more about the test components, sample condition, report delivery, and more.
Test Name: ABL Gene Load Test
Components: Whole Blood, Culture Cells
Price: 900.0 AED
Sample Condition: Whole Blood, Culture Cells
Report Delivery: 3rd Working Day Email: 36 hours. On phone: 24 hours
Method: Real Time PCR
Test Type: Viral
Doctor: Physician
Test Department: Genetics
Pre Test Information: Before undergoing the ABL Gene Load Test, patients need to sign a consent document and bring any clinical history related to the test.
What is the ABL Gene Load Test?
The ABL gene load test is a diagnostic test used to determine the amount or level of the ABL gene in a sample. The ABL gene codes for a protein called Abelson tyrosine kinase, which plays a role in cell signaling and regulation.
This test is commonly used in the field of oncology to monitor and assess the response to treatment in patients with chronic myeloid leukemia (CML). In CML, there is a specific chromosomal abnormality known as the Philadelphia chromosome, which causes the fusion of the ABL gene with another gene called BCR. This fusion gene, called BCR-ABL, produces a protein with abnormal tyrosine kinase activity that promotes the growth and survival of cancer cells.
How is the ABL Gene Load Test performed?
The ABL gene load test is typically performed using a technique called quantitative reverse transcription polymerase chain reaction (qRT-PCR). This involves converting the RNA molecules produced by the BCR-ABL fusion gene into complementary DNA (cDNA) using reverse transcription. The cDNA is then amplified using PCR, and the amount of amplified cDNA is quantified.
The results of the ABL gene load test are reported as a ratio of BCR-ABL transcripts to a control gene, such as the ABL gene itself or another reference gene. This ratio is compared to a standardized baseline or threshold to determine the level of BCR-ABL expression. A lower ratio indicates a lower disease burden and a better response to treatment, while a higher ratio indicates a higher disease burden and a poorer response to treatment.
Benefits of the ABL Gene Load Test
The ABL gene load test is a valuable tool in monitoring and managing CML patients. It provides important information about the disease progression and treatment response, helping healthcare professionals make informed decisions regarding treatment adjustments. Additionally, the test can also be used to detect early signs of relapse.
Don’t wait any longer! Contact DNA Labs UAE today to schedule your ABL Gene Load Test and gain valuable insights into your condition.
| Test Name | ABL Gene Load Test |
|---|---|
| Components | |
| Price | 900.0 AED |
| Sample Condition | Whole Blood, Culture Cells |
| Report Delivery | 3rd Working Day Email:-36 hours.On phone: 24 hours |
| Method | Real Time PCR |
| Test type | Viral |
| Doctor | Physician |
| Test Department: | Genetics |
| Pre Test Information | Need to sign Consent document and bring any clinical history of patient forABL Gene Load Test |
| Test Details |
The ABL gene load test is a diagnostic test used to determine the amount or level of the ABL gene in a sample. The ABL gene is a gene that codes for a protein called Abelson tyrosine kinase, which is involved in cell signaling and regulation. This test is commonly used in the field of oncology to monitor and assess the response to treatment in patients with chronic myeloid leukemia (CML). In CML, there is a specific chromosomal abnormality called the Philadelphia chromosome, which results in the fusion of the ABL gene with another gene called BCR. This fusion gene, known as BCR-ABL, produces a protein with abnormal tyrosine kinase activity that promotes the growth and survival of cancer cells. The ABL gene load test measures the quantity of BCR-ABL transcripts, which are the RNA molecules produced by the BCR-ABL fusion gene. By quantifying the BCR-ABL transcripts, the test can provide information about the disease burden and response to treatment in CML patients. The ABL gene load test is typically performed using a technique called quantitative reverse transcription polymerase chain reaction (qRT-PCR). This technique involves converting the RNA molecules into complementary DNA (cDNA) using reverse transcription, and then amplifying the cDNA using PCR. The amount of amplified cDNA is then quantified, which reflects the level of BCR-ABL transcripts in the sample. The results of the ABL gene load test are reported as a ratio of BCR-ABL transcripts to a control gene, such as the ABL gene itself or another reference gene. This ratio is then compared to a standardized baseline or threshold to determine the level of BCR-ABL expression. A lower ratio indicates a lower disease burden and a better response to treatment, while a higher ratio indicates a higher disease burden and a poorer response to treatment. Overall, the ABL gene load test is a valuable tool in monitoring and managing CML patients, as it provides important information about the disease progression and treatment response. It helps healthcare professionals make informed decisions regarding treatment adjustments and can also be used to detect early signs of relapse. |
