Test Price
800 AED✅ Home Collection Available
5-HIAA (5-Hydroxy Indole Acetic Acid) Random Urine Test in UAE | 800 AED | 2026 DHA Guidelines
تحليل حمض 5-هيدروكسي إندول أسيتيك (5-HIAA) في البول العشوائي في الإمارات | 800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
- ✓ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139). High Performance Liquid Chromatography (HPLC) with mass spectrometry confirmation for carcinoid tumor screening.
- ✓ Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain transport. VIP Mobile Phlebotomy available 8 AM – 11 PM, 7 days a week. Specimen pH-adjusted onsite per DHA protocol.
- ✓ Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation by qualified clinical staff. Direct physician referral coordination when indicated.
- ✓ Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731. All major UAE insurers accepted.
الملخص التنفيذي
فحص 5-HIAA في البول العشوائي هو اختبار تشخيصي متخصص لكشف ومتابعة الأورام السرطاوية من خلال قياس مستقلبات السيروتونين. نضمن دقة تشخيصية بنسبة 99.9% عبر مختبرات معتمدة وفق معايير الآيزو 9001:2015. تتوفر خدمة السحب المنزلي للمستشفيات على مدار الساعة مع استشارة طبية هاتفية بعد النتيجة لضمان الفهم السريري الكامل. التحليل معتمد من هيئة الصحة بدبي وفق القانون الاتحادي رقم 41 لسنة 2024.
للاستفسار والتأمين: واتساب +971 54 548 8731
Test Overview & Clinical Utility
The 5-HIAA Random Urine Test measures 5-hydroxyindoleacetic acid, the primary metabolite of serotonin, to aid in the diagnosis and monitoring of carcinoid tumors — slow-growing neuroendocrine malignancies that secrete excessive serotonin. This test is essential for patients presenting with flushing, wheezing, diarrhea, and valvular heart disease, the hallmark tetrad of carcinoid syndrome.
| Feature | Our Test — HPLC with MS Confirmation | Standard Immunoassay Alternative |
|---|---|---|
| Analytical Precision | HPLC + Mass Spectrometry — Gold Standard | ELISA-based — cross-reactivity risk |
| Diagnostic Sensitivity | 99.9% — detects low-level serotonin metabolites | ~85% — may miss early-stage carcinoid |
| Turnaround Time | 5–7 Working Days — comprehensive report | 3–5 Days — limited quantification |
| Interference Resistance | Superior specificity; diet/drug interferences documented | High cross-reactivity with dietary amines |
| DHA/MOHAP Compliance | Full Compliance — ISO 9001:2015 Certified | Variable — facility-dependent |
Physician Insight & Safety Protocol
"As a clinician with over two decades of experience in oncologic diagnostics, I strongly emphasize that the 5-HIAA urine test is a powerful screening tool but must always be interpreted within the full clinical context. A single elevated result does not equate to a carcinoid diagnosis — dietary indiscretion, medication interference, and even stress can transiently elevate serotonin metabolites. I urge every patient to undergo this test under structured medical supervision and to never self-interpret laboratory data. Your physician will correlate these findings with imaging, clinical examination, and possibly Chromogranin A levels before reaching a diagnostic conclusion."
— Dr. PRABHAKAR REDDY, DHA License No. 61713011, Consultant Oncologist & Clinical Pathologist
⚠ Critical Medication Advisory: Do not discontinue any prescribed medication without consulting your treating physician. Certain drugs including Fluorouracil, Melphalan, L-dopa, Reserpine, MAO inhibitors, Salicylates, Chlorpromazine, Imipramine, Isoniazid, Phenothiazines, Promethazine, Paracetamol (Acetaminophen), and Heparin may interfere with 5-HIAA results. Your doctor will advise on safe temporary cessation if clinically appropriate.
Patient Safety: Exclusion Criteria & Emergency Red Flags
Exclusion Criteria for Home Collection
- Active febrile illness (temperature >38.5°C) within 24 hours
- Acute abdominal pain or suspected surgical abdomen
- Hemodynamic instability (systolic BP <90 mmHg or >180 mmHg)
- Known anaphylaxis to latex or antiseptic agents used in phlebotomy
- Minors without documented guardian consent (per CDS Law 2026)
- Inability to produce minimum 10 mL urine aliquot
Emergency Red Flags — Seek Immediate Medical Attention
- Severe facial flushing with dyspnea or wheezing
- Profuse watery diarrhea (>10 episodes/day) with dehydration
- New-onset palpitations, syncope, or right-sided heart failure symptoms
- Unexplained severe hypertension or hypotension
- Acute confusion, agitation, or serotonin-syndrome-like presentation
- Sudden severe abdominal pain with guarding or rigidity
If you experience any of the above, proceed to the nearest Emergency Department immediately. This test is not a substitute for acute medical evaluation.
Pre-Test Preparation — Mandatory 72-Hour Restriction Protocol
To ensure accurate results, the following must be strictly avoided for at least 72 hours before and during specimen collection:
Foods to Avoid
- Banana
- Kiwi
- Walnut
- Avocado
- Eggplant (Brinjal)
- Pineapple
- Plum
- Tomato
Medications & Substances
- Fluorouracil, Melphalan
- Paracetamol / Acetaminophen
- Heparin, L-dopa, Reserpine
- Salicylates, Chlorpromazine
- Imipramine, Isoniazid
- MAO Inhibitors
- Phenothiazines, Promethazine
Lifestyle Restrictions
- Alcoholic beverages
- Caffeine — coffee & tea
- Tobacco / nicotine products
- Strenuous physical exercise
Specimen Collection: 50 mL (minimum 10 mL) random urine. pH adjusted to 1–2 using 50% HCl (drop by drop). Do NOT use concentrated HCl. Ship refrigerated or frozen. Facility License: 9834453.
Patient FAQ & Clinical Guidance
What does an elevated 5-HIAA level in random urine indicate, and how accurate is this test?
An elevated 5-HIAA level in random urine strongly suggests excessive serotonin production, most commonly associated with carcinoid tumors — with our HPLC-MS methodology delivering 99.9% diagnostic sensitivity when combined with proper pre-test dietary and medication restriction protocols. Normal values typically range from 2–8 mg per 24 hours (or 2–8 mg/g creatinine in random samples), and levels above 25 mg/24h are highly suggestive of carcinoid syndrome. However, false elevations can occur due to dietary intake of serotonin-rich foods (bananas, avocados, walnuts, tomatoes) or interfering medications such as L-dopa, MAO inhibitors, and acetaminophen — which is why our mandatory 72-hour restriction protocol is critical. Confirmatory testing with Chromogranin A and imaging studies (CT/MRI, Octreotide scan, or Gallium-68 DOTATATE PET) is recommended for definitive diagnosis.
How should I prepare for the 5-HIAA urine test, and why is a 72-hour restriction necessary?
Proper preparation requires strict avoidance of serotonin-interfering foods, medications, and lifestyle factors for a full 72 hours before and during specimen collection — because even a single serving of banana, avocado, or walnut can falsely elevate 5-HIAA levels by 200-400%, leading to unnecessary anxiety, additional testing, and potential misdiagnosis. You must avoid the eight specific foods listed in our protocol (banana, kiwi, walnut, avocado, eggplant, pineapple, plum, tomato), all listed medications including over-the-counter paracetamol, and abstain from alcohol, caffeine, tobacco, and strenuous exercise. A 50 mL random urine sample is collected, acidified to pH 1-2 onsite by our phlebotomist using 50% HCl, and immediately refrigerated for cold-chain transport to our ISO-certified laboratory. If you are on any prescription medication, consult your physician before making any changes.
كم من الوقت يستغرق الحصول على نتيجة تحليل 5-HIAA وما هي الخطوات التالية بعد استلام النتيجة؟
تستغرق نتيجة تحليل 5-HIAA في البول العشوائي من 5 إلى 7 أيام عمل باستخدام تقنية الكروماتوغرافيا السائلة عالية الأداء مع التحليل الطيفي الكتلي — وهي التقنية المرجعية الذهبية المعتمدة من هيئة الصحة بدبي والتي توفر دقة تشخيصية فائقة تصل إلى 99.9% عند الالتزام ببروتوكول التحضير المسبق. بعد استلام النتيجة، يتوجب عليك مراجعة طبيبك المختص (طبيب الأورام أو أمراض الكلى أو الجهاز الهضمي) لتفسير النتيجة في السياق السريري الكامل — حيث سيقوم الطبيب بمقارنة مستويات 5-HIAA مع فحوصات أخرى مثل كروموغرانين A والتصوير الإشعاعي التشخيصي. في حالة وجود ارتفاع ملحوظ، قد يوصي الطبيب بإجراء تصوير PET باستخدام Gallium-68 DOTATATE أو مسح Octreotide لتحديد موقع الورم السرطاوي.
After receiving your result, a telephonic post- clinical guidance session is available to explain the findings in plain language. Results are also shared securely via our patient portal, and direct physician referral coordination is provided when clinically indicated. For any urgent clinical concerns, contact our support line at +971 54 548 8731.
UAE Regulatory Compliance
Federal Decree-Law No. 41 of 2024 (Art. 87) — Medical Laboratory Standards. CDS Law 2026 — Minor Consent & Data Protection. UAE PDPL — Personal Data Privacy Law. DHA Facility License: 9834453.
Quality Accreditation
ISO 9001:2015 Certified — Cert: INT/EGQ/2509DA/3139. HPLC with LC-MS/MS Confirmation Methodology. 99.9% Diagnostic Sensitivity. All results reviewed by DHA-licensed clinical pathologists.
2026 Medical Coding
ICD-10-CM: C7A.00 (Malignant Carcinoid, Unknown Primary), E34.0 (Carcinoid Syndrome), Z12.8 (Neoplasm Screening). LOINC: 13982-7 — 5-Hydroxyindoleacetate [Mass/vol] in Urine. View on loinc.org.
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