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5 Fluorouracil 5FU Toxicity Test

1,560 د.إ

-15%

The 5 Fluorouracil (5FU) Toxicity Test is a specialized diagnostic assessment designed to evaluate an individual’s risk of experiencing severe adverse reactions to the chemotherapy drug 5-fluorouracil (5FU) and other fluoropyrimidine-based medications. These drugs are commonly used in the treatment of various cancers, including colorectal, stomach, and breast cancers. The test is particularly significant because a subset of the population has a genetic variation that impairs their ability to metabolize 5FU properly, leading to increased toxicity and severe side effects.

DNA Labs UAE offers this crucial test for individuals undergoing or about to start treatment with 5FU. By analyzing specific genes, such as DPYD and TYMS, that influence the metabolism of 5FU, the test can help identify patients at risk of toxicity. This information enables healthcare providers to adjust the drug dosage or consider alternative treatments, thereby minimizing the risk of severe side effects.

The cost of the 5 Fluorouracil (5FU) Toxicity Test at DNA Labs UAE is 1560 AED. Given the potential for preventing life-threatening side effects, the test represents a critical step in personalizing cancer treatment, ensuring that it is both safe and effective for each patient.

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5 FLUOROURACIL 5FU TOXICITY Test

Test Details:

The 5-fluorouracil (5FU) toxicity test is a laboratory test used to measure the levels of 5FU in the blood to assess its toxicity. 5FU is a chemotherapy drug commonly used to treat various types of cancer, including breast, colon, and stomach cancers. The test is usually performed before starting 5FU treatment and during the course of treatment to monitor the drug’s concentration in the blood. It helps determine if the drug is within the therapeutic range or if it is causing toxicity.

Components:

  • DPYD Gene

Price:

1560.0 AED

Sample Condition:

4 mL (2 mL min.) whole blood from 1 Lavender Top (EDTA) tube. Ship refrigerated. DO NOT FREEZE. Duly filled Genomics clinical Information Requisition Form (Form 20) is mandatory.

Report Delivery:

1 week

Method:

PCR, Sequencing

Test Type:

Pharmacogenomics

Doctor:

Oncologist

Test Department:

MOLECULAR DIAGNOSTICS

Pre Test Information:

Duly filled Genomics clinical Information Requisition Form (Form 20) is mandatory.

Test Procedure:

The test involves drawing a blood sample from the patient, usually through a vein in the arm. The blood sample is then sent to a laboratory for analysis. The laboratory technicians use specialized equipment to measure the concentration of 5FU in the blood. The results of the test are usually reported in micrograms per milliliter (g/mL) or nanograms per milliliter (ng/mL).

Test Results and Interpretation:

The therapeutic range for 5FU varies depending on the specific cancer being treated and the individual patient’s characteristics. Healthcare providers compare the test results with the therapeutic range to determine if the drug dosage needs to be adjusted. Toxic levels of 5FU can lead to severe side effects, such as bone marrow suppression, gastrointestinal problems, and damage to the liver. By monitoring the drug levels, healthcare providers can adjust the dosage or make necessary interventions to prevent or manage toxicity.

Importance of Regular Monitoring:

It is important for patients undergoing 5FU treatment to follow their healthcare provider’s instructions regarding the timing and frequency of the test. Regular monitoring of 5FU levels can help ensure the drug is effective in treating cancer while minimizing the risk of toxicity.

Test Name 5 FLUOROURACIL 5FU TOXICITY Test
Components *DPYD Gene
Price 1560.0 AED
Sample Condition 4 mL (2 mL min.) whole blood from 1 Lavender Top (EDTA) tube. Ship refrigerated. DO NOT FREEZE. Duly filled Genomics clinical Information Requisition Form (Form 20) is mandatory.
Report Delivery 1 week
Method PCR, Sequencing
Test type Pharmacogenomics
Doctor Oncologist
Test Department: MOLECULAR DIAGNOSTICS
Pre Test Information Duly filled Genomics clinical Information Requisition Form (Form 20) is mandatory.
Test Details

The 5-fluorouracil (5FU) toxicity test is a laboratory test used to measure the levels of 5FU in the blood to assess its toxicity. 5FU is a chemotherapy drug commonly used to treat various types of cancer, including breast, colon, and stomach cancers.

The test is usually performed before starting 5FU treatment and during the course of treatment to monitor the drug’s concentration in the blood. It helps determine if the drug is within the therapeutic range or if it is causing toxicity.

Toxic levels of 5FU can lead to severe side effects, such as bone marrow suppression, gastrointestinal problems, and damage to the liver. By monitoring the drug levels, healthcare providers can adjust the dosage or make necessary interventions to prevent or manage toxicity.

The test involves drawing a blood sample from the patient, usually through a vein in the arm. The blood sample is then sent to a laboratory for analysis. The laboratory technicians use specialized equipment to measure the concentration of 5FU in the blood.

The results of the test are usually reported in micrograms per milliliter (g/mL) or nanograms per milliliter (ng/mL). The therapeutic range for 5FU varies depending on the specific cancer being treated and the individual patient’s characteristics. Healthcare providers compare the test results with the therapeutic range to determine if the drug dosage needs to be adjusted.

It is important for patients undergoing 5FU treatment to follow their healthcare provider’s instructions regarding the timing and frequency of the test. Regular monitoring of 5FU levels can help ensure the drug is effective in treating cancer while minimizing the risk of toxicity.