Understanding the complex nature of genetic disorders is crucial for the provision of appropriate medical care and guidance. Among these, the ZBTB24 Gene Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome Type 2 (ICF2) stands out due to its rarity and the unique challenges it presents. DNA Labs UAE is at the forefront of diagnosing this condition through comprehensive genetic testing. This article aims to shed light on the symptoms of ICF2 and the details of the genetic test provided by DNA Labs UAE, including its cost.
Symptoms of ZBTB24 Gene Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome Type 2
ICF syndrome is characterized by a triad of symptoms: immunodeficiency, centromeric instability, and facial anomalies. Specifically, for Type 2, caused by mutations in the ZBTB24 gene, patients may exhibit the following symptoms:
- Immunodeficiency: This is often the most critical aspect of ICF2. Patients may have a significantly reduced ability to fight infections, leading to recurrent respiratory infections, gastrointestinal infections, and an increased risk of autoimmune disorders.
- Centromeric Instability: This refers to abnormalities in the structure of chromosomes, particularly in the centromere region. It is usually detected through specialized genetic testing.
- Facial Anomalies: Individuals with ICF2 may have distinct facial features. These can include a flat nasal bridge, epicanthic folds, and a small lower jaw.
- Growth and Development: Growth delays and developmental challenges are common, including difficulties in speech and motor skills.
It is important to note that the severity and combination of symptoms can vary widely among individuals with ICF2. Early diagnosis and intervention are crucial for managing the condition effectively.
ZBTB24 Gene Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome Type 2 Genetic Test at DNA Labs UAE
DNA Labs UAE offers a comprehensive genetic test for ICF2, targeting the ZBTB24 gene. This test is pivotal for confirming the diagnosis, which can then guide the management and treatment strategies for the affected individuals.
The genetic test involves a detailed analysis of the ZBTB24 gene to identify mutations that cause the syndrome. It is recommended for individuals showing symptoms of ICF2, those with a family history of the condition, or parents who may be carriers of the gene mutation.
The cost of the ZBTB24 gene test at DNA Labs UAE is 4400 AED. This includes the full analysis, a detailed report, and a consultation to discuss the findings. The test is conducted using the latest genetic sequencing technologies, ensuring high accuracy and reliability.
For more information and to schedule a test, visit DNA Labs UAE.
Conclusion
ICF2 is a complex genetic disorder that requires comprehensive care and management. Understanding the symptoms and undergoing genetic testing for the ZBTB24 gene mutation is crucial for individuals and families affected by this condition. DNA Labs UAE provides a reliable genetic test for ICF2, helping to pave the way for better management and care for those affected. With the right support and medical care, individuals with ICF2 can lead fulfilling lives.
