Hyper-IgE Syndrome (HIES), also known as Job’s Syndrome, is a rare, primary immunodeficiency disorder characterized by high levels of serum IgE, eczema, and recurrent skin and lung infections. A significant cause of this syndrome is mutations in the STAT3 gene, leading to what is commonly referred to as STAT3-Hyper-IgE Recurrent Infection Syndrome. Recognizing the symptoms of this genetic condition is crucial for early diagnosis and management. DNA Labs UAE offers a comprehensive genetic test for this syndrome, aiding in the accurate diagnosis and better understanding of the condition.
Symptoms of STAT3-Hyper-IgE Recurrent Infection Syndrome
The symptoms of STAT3-Hyper-IgE Recurrent Infection Syndrome are diverse and affect multiple organ systems. Recognizing these symptoms is the first step towards diagnosis and management:
- Recurrent Skin Infections: Patients often experience recurrent skin infections, such as boils and abscesses, which can be severe and difficult to treat.
- Eczema: Eczema or atopic dermatitis is a common symptom, characterized by itchy, inflamed, and red skin.
- Recurrent Lung Infections: Frequent lung infections, including pneumonia, are hallmark symptoms of this syndrome, which can lead to lung damage over time.
- High Serum IgE Levels: One of the defining characteristics of this condition is elevated levels of IgE in the blood, often reaching tens of thousands IU/ml, far exceeding the normal range.
- Skeletal Abnormalities: Patients may also present with skeletal abnormalities such as scoliosis, craniosynostosis, and a characteristic facial appearance.
- Dental Irregularities: Delayed shedding of primary teeth or retention of baby teeth is another symptom associated with this syndrome.
Early identification of these symptoms is crucial for the management and treatment of STAT3-Hyper-IgE Recurrent Infection Syndrome. Genetic testing plays a pivotal role in the diagnosis of this condition.
Genetic Test for STAT3-Hyper-IgE Recurrent Infection Syndrome
DNA Labs UAE offers a specialized genetic test for STAT3-Hyper-IgE Recurrent Infection Syndrome. This test is designed to detect mutations in the STAT3 gene, providing conclusive evidence of the syndrome. The genetic test is a critical tool for healthcare providers, enabling them to make an accurate diagnosis and tailor treatment plans specifically for the patient’s needs.
The cost of the STAT3 gene Hyper-IgE Recurrent Infection Syndrome Genetic Test is 4400 AED. This investment can significantly impact the patient’s quality of life, offering insights into the condition that were previously unattainable. Early diagnosis can lead to better management of symptoms and a reduction in the frequency and severity of infections.
For more information about the STAT3 gene Hyper-IgE Recurrent Infection Syndrome Genetic Test and to schedule a test, please visit DNA Labs UAE.
In conclusion, STAT3-Hyper-IgE Recurrent Infection Syndrome is a complex condition that requires a comprehensive approach for diagnosis and management. Recognizing the symptoms early and opting for genetic testing can make a significant difference in the lives of those affected. DNA Labs UAE is committed to providing advanced genetic testing services, including the STAT3 gene test, to help patients and healthcare providers navigate the challenges of this rare syndrome.
