In the realm of prenatal diagnostics, the evolution of genetic testing has opened up new avenues for expecting parents to gain insights into their unborn child’s health. Among the forefront of these advancements is the Prenatal Diagnostic Screening by Karyotyping and FISH (Fluorescence In Situ Hybridization) for chromosomes 13, 18, 21, X, and Y. Offered by DNA Labs UAE, this comprehensive test is designed to detect chromosomal abnormalities that could lead to developmental and genetic disorders.
Symptoms Leading to the Recommendation of Prenatal Diagnostic Screening
Typically, prenatal diagnostic screening is recommended when there are indications or risks of genetic abnormalities. These can arise from various factors such as advanced maternal age, family history of genetic disorders, or abnormal results from previous prenatal screenings. Specific symptoms and conditions that may prompt a healthcare provider to recommend this screening include:
- Abnormal ultrasound findings
- Increased risk of Down syndrome, Edwards syndrome, or Patau syndrome
- History of miscarriages or stillbirths
- Parental concerns about genetic diseases due to family history
Understanding Karyotyping and FISH
Karyotyping is a laboratory technique that allows scientists to view an individual’s chromosomes in a cell. It helps in identifying and evaluating the size, shape, and number of chromosomes, thereby detecting any abnormalities. On the other hand, FISH is a more targeted approach that uses fluorescent probes to visualize specific chromosomes or parts of chromosomes. It is particularly useful in detecting microdeletions or duplications that might not be visible through karyotyping.
What Does the Test Screen For?
The Prenatal Diagnostic Screening by Karyotyping and FISH for 13, 18, 21, X, and Y chromosomes focuses on identifying abnormalities associated with the most common chromosomal conditions:
- Trisomy 13 (Patau Syndrome): Characterized by severe intellectual disability and physical abnormalities in many parts of the body.
- Trisomy 18 (Edwards Syndrome): Associated with a high rate of miscarriage. Babies that are born often have complex medical and developmental problems.
- Trisomy 21 (Down Syndrome): The most common chromosomal condition, known for causing intellectual disabilities and distinctive facial features.
- Monosomy X (Turner Syndrome): Affects females, leading to short stature and infertility, among other health issues.
- Klinefelter Syndrome (XXY): Affects males, leading to infertility and other physical changes.
Test Cost and Procedure
The cost of the Prenatal Diagnostic Screening by Karyotyping and FISH for 13, 18, 21, X, and Y chromosomes at DNA Labs UAE is 3600 AED. The procedure involves collecting a sample of the amniotic fluid or chorionic villus sampling (CVS) from the pregnant woman. This sample is then analyzed in the laboratory using both karyotyping and FISH techniques to identify any chromosomal abnormalities.
Why Choose DNA Labs UAE?
Choosing DNA Labs UAE for prenatal diagnostic screening comes with the assurance of accuracy, confidentiality, and support. The lab is equipped with state-of-the-art technology and staffed by a team of expert geneticists and counselors who provide comprehensive support throughout the testing process. For more information on this test, visit DNA Labs UAE.
Conclusion
Prenatal diagnostic screening by karyotyping and FISH for chromosomes 13, 18, 21, X, and Y offers expecting parents a valuable tool for early detection of chromosomal abnormalities. While the decision to undergo such testing is deeply personal, understanding the symptoms, procedure, and benefits can help in making an informed choice. DNA Labs UAE stands ready to provide this crucial service, combining expertise with compassionate care to support families during this important part of their journey.
