Symptoms of OGDH Gene Alpha-Ketoglutarate Dehydrogenase Deficiency Genetic Test
The OGDH gene is responsible for encoding a subunit of the alpha-ketoglutarate dehydrogenase complex, an enzyme critical for the Krebs cycle, a key energy-producing process in the mitochondria. Deficiency in this enzyme due to mutations in the OGDH gene can lead to a range of metabolic and neurological symptoms, making it crucial for affected individuals to undergo genetic testing. DNA Labs UAE offers a comprehensive genetic test for OGDH gene alpha-ketoglutarate dehydrogenase deficiency, ensuring accurate diagnosis and the possibility of tailored management plans for affected individuals.
Understanding the Symptoms
Symptoms of OGDH gene alpha-ketoglutarate dehydrogenase deficiency can vary widely among individuals but generally involve neurological and metabolic disturbances. These symptoms may include:
- Developmental delay and intellectual disability
- Muscle weakness and hypotonia (reduced muscle tone)
- Ataxia (lack of muscle coordination affecting speech, eye movements, and ability to swallow)
- Seizures, which can vary in severity and frequency
- Lactic acidosis, a buildup of lactate in the body which can lead to nausea, vomiting, abdominal pain, and rapid breathing
- Episodes of encephalopathy, which can manifest as confusion, lethargy, and coma in severe cases
Early diagnosis through genetic testing is critical for managing symptoms and improving the quality of life for those affected by this deficiency.
Why Choose DNA Labs UAE for Genetic Testing?
DNA Labs UAE is at the forefront of genetic testing, offering a specialized test for OGDH gene alpha-ketoglutarate dehydrogenase deficiency. The test cost is 3200 AED, reflecting the comprehensive nature of this analysis, which includes detailed genetic counseling and support throughout the process. By choosing DNA Labs UAE, individuals can expect:
- Accurate and reliable genetic testing conducted by experienced professionals
- Comprehensive pre- and post-test counseling to help understand the implications of test results
- A detailed report that explains the findings in an understandable manner
- Guidance on management and treatment options based on the latest research
For more information and to schedule a test, please visit DNA Labs UAE.
Conclusion
OGDH gene alpha-ketoglutarate dehydrogenase deficiency is a rare but potentially serious condition that can lead to a variety of metabolic and neurological symptoms. Understanding the symptoms and undergoing timely genetic testing can be crucial steps in managing this condition effectively. DNA Labs UAE provides a reliable genetic test for this deficiency, helping individuals and families navigate the challenges associated with this condition with confidence and support.
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