Symptoms of MM Panel Cytogenetics and FISH del11q del13q IgH del17p Test
Multiple Myeloma (MM) is a type of blood cancer that affects the plasma cells in the bone marrow. These cancerous cells can cause damage to the bones, immune system, kidneys, and red blood cell count. Identifying the genetic abnormalities associated with multiple myeloma can be crucial for determining the prognosis and tailoring the most effective treatment strategies. One such advanced diagnostic test is the MM Panel Cytogenetics and FISH del11q del13q IgH del17p Test, offered by DNA Labs UAE. This test is designed to detect specific genetic deletions and abnormalities that are often found in multiple myeloma patients, including deletions at 11q, 13q, and 17p, as well as rearrangements involving the immunoglobulin heavy chain (IgH) gene.
Understanding the Symptoms Linked to These Genetic Abnormalities
Patients with multiple myeloma may not initially present with symptoms, which makes genetic testing an important tool for early detection and management. However, when symptoms do appear, they can vary widely depending on the progression of the disease and the specific genetic abnormalities present. Common symptoms associated with multiple myeloma include:
- Bone pain: Especially in the spine or chest, which can be a result of bone damage from proliferating cancer cells.
- Anemia: A decrease in red blood cells causing fatigue and weakness, which can occur when the bone marrow is overcrowded with cancer cells.
- Increased susceptibility to infections: Due to the impact of myeloma on the immune system.
- High levels of calcium in the blood: Resulting from bone breakdown, which can cause excessive thirst, nausea, constipation, and confusion.
- Kidney dysfunction: As a result of the buildup of myeloma protein in the kidneys.
- Weight loss and decreased appetite: Common in individuals with advanced disease.
Identifying the presence of deletions such as del11q, del13q, and del17p, as well as IgH rearrangements, can help predict the aggressiveness of the disease and guide treatment decisions. For example, the deletion of chromosome 17p (del17p) is associated with a poorer prognosis and may influence the choice of therapy to more aggressive treatments.
The Role of MM Panel Cytogenetics and FISH Test in Diagnosis and Management
The MM Panel Cytogenetics and FISH del11q del13q IgH del17p Test plays a critical role in the diagnosis and management of multiple myeloma. By detecting specific genetic abnormalities, healthcare providers can better understand the disease’s behavior, predict its progression, and customize treatment plans to improve patient outcomes. This test is particularly important for newly diagnosed patients and those who have relapsed or shown resistance to standard treatments.
The cost of the MM Panel Cytogenetics and FISH Test at DNA Labs UAE is 3600 AED. While the cost may seem significant, the value it brings in enabling a personalized treatment approach that can lead to better outcomes and potentially extended survival for multiple myeloma patients is immeasurable.
For more detailed information about the MM Panel Cytogenetics and FISH del11q del13q IgH del17p Test and to schedule an appointment, please visit DNA Labs UAE.
Early detection and precise diagnosis are key to effectively managing multiple myeloma. With advancements in genetic testing, such as the MM Panel Cytogenetics and FISH Test, patients have a better chance at a tailored treatment strategy, offering hope to those affected by this complex disease.
