Symptoms of LRBA Gene Immunodeficiency Common Variable Type 8 Genetic Test
The LRBA gene plays a pivotal role in the human immune system, and mutations in this gene can lead to a condition known as LRBA deficiency. This deficiency falls under the broader category of immunodeficiency disorders, specifically classified as Common Variable Immunodeficiency Type 8 (CVID8). Recognizing the symptoms associated with LRBA deficiency is crucial for early diagnosis and management of the condition. DNA Labs UAE offers a comprehensive genetic test to identify mutations in the LRBA gene, providing invaluable information for affected individuals and their families.
Understanding LRBA Deficiency
LRBA deficiency is a rare genetic disorder that impairs the body’s immune system, making it difficult to fight off infections effectively. This condition is autosomal recessive, meaning that an individual must inherit two copies of the mutated gene, one from each parent, to develop the disorder. The LRBA gene itself is essential for the proper functioning of immune cells, and mutations can lead to a range of immune system problems.
Key Symptoms of LRBA Deficiency
The symptoms of LRBA deficiency can vary widely among affected individuals but generally include:
- Recurrent infections: Individuals with LRBA deficiency often experience frequent bacterial, viral, and fungal infections due to the weakened immune system.
- Autoimmune disorders: The condition can lead to the development of autoimmune diseases, where the immune system mistakenly attacks the body’s own tissues.
- Chronic diarrhea: Gastrointestinal issues, including persistent diarrhea, are common in individuals with LRBA deficiency.
- Failure to thrive: Children with LRBA deficiency may experience growth delays or failure to gain weight appropriately.
- Respiratory issues: Recurrent respiratory infections, such as pneumonia and bronchitis, are frequently observed.
It’s important to note that the severity and combination of symptoms can vary significantly from one individual to another.
LRBA Gene Immunodeficiency Common Variable Type 8 Genetic Test at DNA Labs UAE
DNA Labs UAE offers a specialized genetic test designed to detect mutations in the LRBA gene, aiding in the diagnosis of LRBA deficiency. The test is an essential tool for individuals experiencing symptoms suggestive of immunodeficiency disorders or for those with a family history of LRBA deficiency. Early and accurate diagnosis can lead to better management of the condition, improving the quality of life for affected individuals.
The cost of the LRBA Gene Immunodeficiency Common Variable Type 8 Genetic Test is 4400 AED. For more information on the test and how to proceed with testing, please visit our website at DNA Labs UAE.
Conclusion
LRBA deficiency is a complex condition that can significantly impact an individual’s health and quality of life. Recognizing the symptoms early on and undergoing genetic testing can provide a clear diagnosis, guiding treatment and management strategies. DNA Labs UAE is committed to providing accurate and comprehensive genetic testing services, including the LRBA Gene Immunodeficiency Common Variable Type 8 Genetic Test, to support individuals and families affected by this condition.
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