Pachyonychia Congenita (PC) is a rare genetic disorder that primarily affects the skin and nails. It is characterized by a variety of symptoms that can significantly impact the quality of life of those affected. One specific subtype of this condition, known as Pachyonychia Congenita Type 3, is linked to mutations in the KRT6A gene. Understanding the symptoms of this condition is crucial for early diagnosis and management. DNA Labs UAE offers a genetic test specifically designed to identify mutations in the KRT6A gene, aiding in the diagnosis of Pachyonychia Congenita Type 3. This test is priced at 4400 AED. For more information, please visit DNA Labs UAE.
Symptoms of KRT6A Gene Pachyonychia Congenita Type 3
Pachyonychia Congenita Type 3 is a condition that manifests in several ways, primarily affecting the skin, nails, and, in some cases, the mouth and eyes. The symptoms can vary significantly from one individual to another but generally include the following:
- Thickened Nails: One of the hallmark symptoms of PC is the thickening of the nails on both hands and feet. This can lead to discomfort and difficulty in performing daily tasks.
- Painful Plantar Keratoderma: Many individuals with PC experience painful calluses on the soles of their feet. These calluses can make walking or standing uncomfortable or even painful.
- Oral Lesions: Mouth sores or leukokeratosis (white patches) inside the mouth are common among those with PC, including those with the Type 3 variant.
- Follicular Keratosis: This symptom involves the development of small, hard bumps around hair follicles, primarily on the elbows and knees.
- Cysts: Some individuals may develop cysts in various parts of the body, including the scalp, back, and underarms.
It’s important to note that the severity and combination of symptoms can vary widely among individuals. Early diagnosis through genetic testing can provide valuable information for managing the condition.
Genetic Test for KRT6A Gene Pachyonychia Congenita Type 3
DNA Labs UAE offers a comprehensive genetic test for the KRT6A gene to help diagnose Pachyonychia Congenita Type 3. This test is specifically designed to identify mutations in the KRT6A gene that are responsible for the condition. The test is priced at 4400 AED and can provide crucial information for individuals and families affected by PC.
Early diagnosis is key to managing the symptoms of PC effectively. With the right interventions, individuals with PC can lead a more comfortable life. The genetic test offered by DNA Labs UAE is a valuable tool in the diagnostic process, providing a clear understanding of the genetic underpinnings of the condition.
For more information on the KRT6A gene Pachyonychia Congenita Type 3 genetic test and to schedule a test, please visit DNA Labs UAE. Early diagnosis and intervention can make a significant difference in the lives of those affected by Pachyonychia Congenita Type 3.
