Pachyonychia Congenita (PC) is a rare genetic disorder that primarily affects the skin and nails. It is caused by mutations in several genes, including the KRT16 gene, which plays a crucial role in the development and maintenance of the skin and its appendages. DNA Labs UAE offers a comprehensive genetic test for the KRT16 gene to diagnose Pachyonychia Congenita Type 1, providing vital information for affected individuals and their families. This article delves into the symptoms of this condition and details the genetic testing process available at DNA Labs UAE.
Symptoms of Pachyonychia Congenita Type 1
Pachyonychia Congenita Type 1, caused by mutations in the KRT16 gene, manifests through a variety of symptoms primarily affecting the skin and nails. The most common symptoms include:
- Thickened Nails: One of the hallmark symptoms of PC Type 1 is the thickening of the nails on both hands and feet, which can cause discomfort and affect mobility.
- Painful Skin Lesions: Individuals with PC Type 1 often develop painful blisters and calluses on the soles of their feet, which can severely impact their ability to walk and perform daily activities.
- Oral Leukokeratosis: White patches may appear on the tongue and inside of the mouth, which are generally not painful but can be a source of discomfort.
- Follicular Keratosis: This symptom involves the development of small, bump-like lesions around hair follicles, primarily on the elbows and knees.
- Palmoplantar Keratoderma: A thickening of the skin on the palms of the hands and soles of the feet, which can be both painful and uncomfortable.
These symptoms can vary significantly in severity among individuals, and the impact on quality of life can be substantial. Early and accurate diagnosis through genetic testing is crucial for managing the condition effectively.
KRT16 Gene Pachyonychia Congenita Type 1 Genetic Test at DNA Labs UAE
DNA Labs UAE offers a specialized genetic test for diagnosing Pachyonychia Congenita Type 1. This test specifically looks for mutations in the KRT16 gene, which are responsible for the condition. The process involves collecting a small sample of saliva or blood from the patient, which is then analyzed in our state-of-the-art laboratory. Our team of experts uses advanced genetic sequencing techniques to identify any mutations in the KRT16 gene that may be causing the condition.
The cost of the KRT16 gene Pachyonychia Congenita Type 1 genetic test is 4400 AED. While the price may seem high, it is a valuable investment in your health and well-being, providing crucial information for managing the condition and improving quality of life.
For more information and to schedule a test, please visit our website at DNA Labs UAE.
Why Choose DNA Labs UAE for Your Genetic Testing Needs?
DNA Labs UAE is a leading provider of genetic testing services in the United Arab Emirates. Our laboratory is equipped with the latest technology, and our team of geneticists and medical professionals are highly trained and experienced in the field of genetic diagnostics. We are committed to providing accurate, reliable, and confidential genetic testing services to our clients. By choosing DNA Labs UAE for your KRT16 gene test, you are ensuring that you receive the highest standard of care and the most precise results available.
Understanding the genetic basis of Pachyonychia Congenita Type 1 through the KRT16 gene test can significantly impact the management and treatment of the condition. It enables affected individuals and their families to make informed decisions about their health and lifestyle, potentially reducing the severity of symptoms and improving overall quality of life.
If you or a loved one are experiencing symptoms consistent with Pachyonychia Congenita Type 1, consider scheduling a genetic test with DNA Labs UAE today. Early diagnosis can be a crucial step in managing the condition effectively and leading a healthier, more comfortable life.
