Focal Segmental Glomerulosclerosis (FSGS) is a complex kidney disorder characterized by scarring (sclerosis) in the kidney’s filtering units, known as glomeruli. This condition can lead to severe kidney damage and, ultimately, kidney failure. Among the genetic variants contributing to the development of FSGS, mutations in the INF2 gene are significant, leading to a specific subtype known as Focal Segmental Glomerulosclerosis Type 5. Recognizing the symptoms of this genetic condition is crucial for early diagnosis and management. DNA Labs UAE offers a comprehensive genetic test for this condition, providing a pivotal resource for individuals and families affected by this challenging disease.
Symptoms of INF2 Gene Focal Segmental Glomerulosclerosis Type 5
The symptoms associated with FSGS Type 5 due to INF2 gene mutations can vary widely among individuals but typically include the following:
- Proteinuria: Excessive levels of protein in the urine, which can lead to frothy urine or swelling in the body (edema), particularly around the eyes, feet, and ankles.
- Hematuria: Blood in the urine, which may be visible to the naked eye or detectable only through a urine test.
- Hypertension: High blood pressure, which can be difficult to control and may contribute to further kidney damage.
- Progressive Kidney Failure: A gradual loss of kidney function, which may lead to symptoms such as fatigue, weakness, and changes in urine output.
It’s important to note that these symptoms can develop gradually and may initially be mild or attributed to other causes. Early detection through genetic testing can provide valuable information for managing the condition effectively.
Genetic Test for INF2 Gene Focal Segmental Glomerulosclerosis Type 5
DNA Labs UAE offers a specialized genetic test designed to identify mutations in the INF2 gene associated with FSGS Type 5. This test is a crucial tool for individuals who have a family history of FSGS or who exhibit symptoms of the disease. The genetic test involves a simple blood draw or saliva sample, and the process is straightforward and minimally invasive.
The cost of the genetic test for INF2 Gene Focal Segmental Glomerulosclerosis Type 5 at DNA Labs UAE is 4400 AED. While the cost may seem significant, it’s important to consider the value of early diagnosis and the potential to tailor treatment strategies based on the genetic findings. Early intervention can slow the progression of kidney damage and improve the quality of life for those affected by this condition.
For more information about the genetic test and to schedule an appointment, please visit DNA Labs UAE.
Conclusion
Focal Segmental Glomerulosclerosis Type 5 due to INF2 gene mutations presents a significant challenge to affected individuals and their families. However, advances in genetic testing offer hope for early diagnosis and personalized treatment plans. DNA Labs UAE is at the forefront of providing such genetic testing services, enabling patients and healthcare providers to take proactive steps in managing the condition. Recognizing the symptoms and understanding the importance of genetic testing are the first steps toward better outcomes for those impacted by this form of FSGS.
