Understanding Immunohistochemistry Microsatellite Instability Panel Test
At DNA Labs UAE, we offer a comprehensive range of genetic tests, including the Immunohistochemistry Microsatellite Instability (MSI) Panel Test. This test plays a crucial role in diagnosing and managing various types of cancer. Microsatellite instability is a condition of genetic hypermutability (predisposition to mutation) that results from impaired DNA mismatch repair (MMR). The test is particularly significant in the context of colorectal cancer, among others, where it can guide treatment decisions and provide prognostic information.
Symptoms Leading to the Recommendation of MSI Testing
The decision to proceed with MSI testing is often based on certain symptoms or clinical scenarios that suggest a higher risk of cancers associated with Lynch Syndrome or other conditions leading to MSI. These symptoms include:
- Family History: A strong family history of colorectal cancer, endometrial cancer, or other Lynch Syndrome-associated cancers.
- Early Onset of Cancer: Diagnosis of cancer at a younger age, especially if diagnosed before the age of 50.
- Multiple Cancers: Individuals who have been diagnosed with more than one cancer, particularly if at least one is a Lynch Syndrome-associated cancer.
- Abnormal Cancer Screening Results: Abnormal results from previous cancer screenings that may indicate Lynch Syndrome or other genetic conditions leading to an increased risk of cancer.
What Does the Immunohistochemistry Microsatellite Instability Panel Test Involve?
The Immunohistochemistry Microsatellite Instability Panel Test involves analyzing cancer tissue to check for the presence of proteins produced by the MMR genes. The absence of one or more of these proteins suggests microsatellite instability. This test is a less invasive option and can serve as a preliminary step before more comprehensive genetic testing for Lynch Syndrome and other conditions.
Benefits of the MSI Panel Test
There are several benefits to undergoing an MSI Panel Test, including:
- Targeted Treatment: Identifying MSI can help in tailoring cancer treatment more effectively. For instance, tumors with high levels of MSI may respond better to certain types of immunotherapy.
- Prognostic Value: The presence of MSI has been associated with a better overall prognosis in certain types of cancer.
- Risk Assessment: For individuals with cancer, identifying MSI can help assess the risk of developing other cancers, potentially leading to more personalized surveillance strategies.
- Family Planning: For families with a history of Lynch Syndrome, MSI testing can provide valuable information for genetic counseling and decision-making regarding family planning.
Cost of the Immunohistochemistry Microsatellite Instability Panel Test
At DNA Labs UAE, we are committed to providing our clients with accessible and high-quality diagnostic services. The cost of the Immunohistochemistry Microsatellite Instability Panel Test is set at 2020 AED. This price reflects our dedication to offering advanced genetic testing solutions at competitive rates.
Why Choose DNA Labs UAE?
Choosing DNA Labs UAE for your genetic testing needs ensures access to state-of-the-art facilities, highly qualified professionals, and a commitment to accuracy and confidentiality. Our Immunohistochemistry Microsatellite Instability Panel Test is conducted with the utmost precision, providing you with reliable results that can guide your healthcare decisions. For more information on this test and to schedule your appointment, please visit our website at https://dnalabsuae.com/tests/immunohistochemistry-microsatellite-instability-panel-test/.
At DNA Labs UAE, we understand the importance of reliable, accurate genetic testing in managing your health and well-being. Our team is dedicated to providing you with the support and information you need throughout the testing process, ensuring that you make informed decisions about your healthcare. Trust us to be your partner in navigating the complexities of genetic health.
