Symptoms and Testing information for Immunohistochemistry H3K27M H3K27me3 Test

Symptoms and Testing information for Immunohistochemistry H3K27M H3K27me3 Test

In the realm of medical diagnostics, the precision and specificity of tests are paramount to understanding and treating various conditions. One such advanced diagnostic approach is the Immunohistochemistry H3K27M H3K27me3 Test, a specialized test offered by DNA Labs UAE. This test plays a crucial role in the diagnosis and management of certain types of brain tumors, specifically those involving alterations in the H3K27M and H3K27me3 proteins. Understanding the symptoms that necessitate this test, its implications, and the logistics surrounding it, such as cost, is essential for patients and healthcare providers alike.

Symptoms Necessitating the H3K27M H3K27me3 Test

The H3K27M H3K27me3 test is primarily used in the context of neurological conditions, particularly brain tumors. The mutation of the H3K27M gene and the subsequent alterations in the H3K27me3 protein expression are closely associated with certain high-grade gliomas. Patients who exhibit symptoms indicative of such tumors may be recommended for this test. These symptoms include, but are not limited to:

  • Headaches that worsen over time
  • Seizures or convulsions
  • Neurological deficits such as weakness, numbness, or loss of coordination
  • Changes in personality or cognitive functions
  • Visual disturbances

These symptoms are not exclusive to tumors with H3K27M mutations but are concerning for a possible underlying brain tumor. The specific detection of H3K27M mutation and H3K27me3 protein expression through immunohistochemistry provides valuable information for diagnosis and treatment planning.

Understanding the Test and Its Implications

The Immunohistochemistry H3K27M H3K27me3 Test is a sophisticated diagnostic tool that involves examining tumor tissue samples under a microscope with specific antibodies that react with the H3K27M and H3K27me3 proteins. This test helps in identifying the presence of these proteins, thereby indicating the mutation status of the tumor. The presence of H3K27M mutation and altered H3K27me3 expression is a significant marker for certain pediatric and adult brain tumors, influencing treatment decisions and prognostication.

Test Cost and Availability

Understanding the financial aspect of medical testing is crucial for patients and their families. At DNA Labs UAE, the Immunohistochemistry H3K27M H3K27me3 Test is offered at a cost of 590 AED. This cost is reflective of the specialized nature of the test and the valuable insights it provides for managing complex brain tumors. For more information on the test and to schedule an appointment, interested individuals can visit DNA Labs UAE.

Conclusion

The Immunohistochemistry H3K27M H3K27me3 Test represents a critical advancement in the diagnostic capabilities for brain tumors. By identifying specific genetic mutations and protein expressions, this test aids in the accurate diagnosis, treatment planning, and prognostication of brain tumors. Recognizing the symptoms that may warrant this test, understanding its implications, and being aware of its cost are important steps in accessing the necessary care. DNA Labs UAE is committed to providing this essential service, supporting patients and healthcare providers in the fight against brain tumors.

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