In the realm of medical diagnostics, the evolution of testing methodologies has been pivotal in the early detection and treatment of various diseases. Among these advancements, Immunohistochemistry (IHC) stands out, particularly the DOG-1 test, which has become a cornerstone in identifying gastrointestinal stromal tumors (GISTs). DNA Labs UAE, a leading genetic laboratory, offers a comprehensive Immunohistochemistry DOG-1 Test, designed to detect the presence of Discovered on GIST-1 protein, which is crucial for diagnosing GISTs. This article aims to elucidate the symptoms that necessitate the DOG-1 test, its significance, and the associated cost.
Symptoms Necessitating the DOG-1 Test
Gastrointestinal stromal tumors (GISTs) often remain asymptomatic in their early stages, making them challenging to diagnose. However, as they grow, they can exhibit symptoms that should prompt further investigation through tests like DOG-1. Symptoms indicative of GISTs and warranting the DOG-1 test include:
- Abdominal pain or discomfort, often the first indicator.
- Noticeable lump or mass in the abdomen.
- Feeling of fullness, even after eating a small meal.
- Blood in stool or vomit, indicating potential bleeding within the gastrointestinal tract.
- Anemia caused by chronic bleeding leading to fatigue and weakness.
- Unintended weight loss, which can be a sign of various cancers, including GISTs.
Understanding the DOG-1 Test
The DOG-1 test is a specialized Immunohistochemistry assay designed to detect the DOG-1 protein, which is overexpressed in the majority of GISTs. This test is performed on a tissue sample, usually obtained through a biopsy of the suspected tumor. The presence of DOG-1 protein is a strong indicator of GIST, making this test a crucial component in the diagnostic process. It helps differentiate GISTs from other types of tumors within the gastrointestinal tract, ensuring accurate diagnosis and appropriate treatment planning.
Significance of the DOG-1 Test
The early detection of GISTs can significantly impact the treatment outcome. The DOG-1 test plays a vital role in not only diagnosing GISTs but also in determining the prognosis and guiding the treatment strategy. It is particularly important for identifying tumors that do not express the more commonly known c-KIT protein, thereby broadening the spectrum of diagnosable GISTs. Furthermore, the test’s results can influence decisions regarding surgical resection, the necessity of adjuvant therapy, and the selection of targeted therapies, making it an indispensable tool in the management of GISTs.
Cost of the DOG-1 Test at DNA Labs UAE
At DNA Labs UAE, the Immunohistochemistry DOG-1 Test is offered at a cost of 410 AED. This price reflects the comprehensive nature of the test, including the meticulous process of tissue sampling, preparation, and the specialized staining technique required to identify the DOG-1 protein. Given the test’s importance in the accurate diagnosis and treatment planning for GISTs, it represents a valuable investment in health. For more information or to schedule a test, please visit DNA Labs UAE.
Conclusion
Recognizing the symptoms that may indicate a gastrointestinal stromal tumor is crucial for timely diagnosis and treatment. The Immunohistochemistry DOG-1 Test, available at DNA Labs UAE, is a key diagnostic tool in identifying these tumors, offering hope for affected individuals through early detection. With a cost of 410 AED, it is an accessible option for those seeking answers and a path towards effective treatment. Understanding the significance of this test and recognizing the symptoms that necessitate it can be the first steps towards a successful recovery journey.
