Understanding the Immunohistochemistry CD45 LCA Test
The Immunohistochemistry CD45 LCA Test is a specialized diagnostic tool used in medical laboratories to identify and analyze the presence of leukocyte common antigen (LCA) in tissue samples. This test plays a crucial role in diagnosing various hematologic malignancies and immune disorders. CD45, a transmembrane protein tyrosine phosphatase, is widely expressed on the surface of all leukocytes, including lymphocytes, monocytes, granulocytes, and eosinophils, making it an essential marker for immunophenotyping in pathological investigations.
Symptoms Necessitating the CD45 LCA Test
Patients may be advised to undergo the CD45 LCA Test for a variety of reasons, primarily related to symptoms indicating potential lymphoid malignancies or other immune system-related disorders. Some of these symptoms include:
- Unexplained lymphadenopathy (swelling of the lymph nodes)
- Persistent fever without a known cause
- Night sweats and unexplained weight loss
- Fatigue and weakness that does not improve with rest
- Splenomegaly (enlargement of the spleen) or hepatomegaly (enlargement of the liver)
- Abnormal findings in blood tests, such as an unexplained increase in white blood cell count
These symptoms, while not exclusively indicative of cancer or immune disorders, warrant further investigation to rule out serious conditions. The CD45 LCA Test provides valuable information that aids in the diagnosis and classification of hematologic malignancies and helps in determining the appropriate course of treatment.
How the CD45 LCA Test Is Conducted
The test involves the collection of a tissue sample, typically through a biopsy of the affected organ or lymph node. This sample is then processed and stained using specific antibodies against the CD45 antigen. Under a microscope, the presence of CD45-positive cells can be detected, providing crucial information about the tissue’s cellular composition and the potential presence of malignancies.
Benefits of the CD45 LCA Test
This test offers several benefits in the clinical setting:
- Accuracy in Diagnosis: It provides a high level of specificity and sensitivity in identifying lymphoid cells and differentiating between various types of leukemias and lymphomas.
- Guidance for Treatment: The results can guide oncologists in choosing the most appropriate treatment plan, including chemotherapy, radiation therapy, or targeted therapies.
- Monitoring Disease Progression: For patients already diagnosed with a hematologic malignancy, the CD45 LCA Test can monitor disease progression or remission.
Test Cost
The cost of the Immunohistochemistry CD45 LCA Test at DNA Labs UAE is set at 410 AED. This price reflects the comprehensive analysis and detailed reporting provided by the laboratory’s experienced specialists. For more detailed information about the test and to schedule an appointment, please visit DNA Labs UAE.
Conclusion
The Immunohistochemistry CD45 LCA Test is a vital diagnostic tool in the field of hematology and oncology, providing critical insights into the nature of various immune and hematologic conditions. Its role in diagnosing, classifying, and monitoring diseases makes it indispensable for healthcare providers and patients alike. With the test readily available at DNA Labs UAE for 410 AED, individuals showing symptoms suggestive of lymphoid malignancies or other immune disorders are encouraged to consult their healthcare provider for further advice and testing.
