In the ever-evolving field of medical science, precision and accuracy in diagnostics play pivotal roles in determining the course of treatment and ultimately, the patient’s outcome. Among the various diagnostic tools available, Immunohistochemistry (IHC) stands out for its ability to localize specific antigens in tissue sections with the help of antigen-antibody interactions that are visualized through a marker. One such marker that has garnered attention in recent years is CD163, which is primarily used to identify cells of the monocyte/macrophage lineage. This test, offered by DNA Labs UAE, is an invaluable tool in the diagnosis and research of various conditions, including inflammatory diseases and certain types of cancer.
Understanding the CD163 Marker
CD163 is a protein encoded by the CD163 gene in humans. It is a member of the scavenger receptor cysteine-rich (SRCR) superfamily and is exclusively expressed on the surface of monocytes and macrophages. Functionally, CD163 is involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes, thereby playing a critical role in anti-inflammatory processes. Due to its specific expression on certain cell types, CD163 serves as an important marker for identifying macrophages in tissue sections.
Symptoms Necessitating the CD163 Test
While the CD163 test itself is a diagnostic tool rather than a symptom, the need for this test arises in the context of various medical conditions that exhibit certain symptoms or clinical presentations. These include:
- Unexplained chronic inflammation
- Symptoms of autoimmune diseases
- Signs suggestive of certain types of cancers, particularly those affecting the hematopoietic system
- Conditions where macrophage activation or proliferation is a concern
- Monitoring the effectiveness of certain treatments targeting macrophages
Physicians might recommend the CD163 test as part of a diagnostic workup in patients presenting with these symptoms to better understand the underlying pathology and to tailor treatment strategies effectively.
Procedure and Test Cost
The Immunohistochemistry CD163 test is performed on a tissue sample, typically obtained through a biopsy of the affected area. This sample is then processed and stained using specific antibodies against CD163. The presence and distribution of CD163-expressing cells can provide valuable insights into the condition being investigated. DNA Labs UAE offers this highly specialized test at a cost of 510 AED. For more information and to schedule a test, interested parties can visit https://dnalabsuae.com/tests/immunohistochemistry-cd163-test/.
Importance of the CD163 Test in Medical Diagnostics
The CD163 test plays a crucial role in the diagnostic process for several reasons. Firstly, it helps in the accurate identification of macrophages in tissue samples, which can be indicative of various pathological conditions. Secondly, it aids in differentiating between different types of inflammatory and neoplastic conditions, thereby guiding the treatment approach. Lastly, monitoring the expression of CD163 can also be useful in assessing the response to certain treatments, especially in diseases where macrophages play a key role in the pathology.
In conclusion, the Immunohistochemistry CD163 test is a powerful diagnostic tool that adds precision to the diagnosis and management of various diseases. By offering this test, DNA Labs UAE contributes significantly to the field of medical diagnostics, aiding healthcare professionals in delivering targeted and effective care to their patients. The availability of this test at a reasonable cost further ensures that more patients can benefit from advanced diagnostic techniques, marking a step forward in personalized medicine.
