Understanding the implications of Human Leukocyte Antigen (HLA) antibodies, particularly Panel Reactive Antibodies (PRA) Class II, is crucial for individuals undergoing organ transplantation or facing autoimmune conditions. The presence of these antibodies can significantly affect the success rate of transplants and the management of autoimmune diseases. DNA Labs UAE offers a comprehensive HLA – Panel Reactive IgG Antibodies PRA Class II Quantitative Test, priced at 2460 AED, to assess the presence and concentration of these antibodies. This test plays a pivotal role in pre-transplant evaluation and in monitoring patients with autoimmune disorders.
What are HLA Panel Reactive IgG Antibodies PRA Class II?
Human Leukocyte Antigens (HLA) are proteins found on the surface of most cells in the human body. They play a critical role in the immune system’s ability to distinguish between self and non-self. The immune system can produce antibodies against HLA antigens, known as HLA antibodies, in response to exposure to foreign human tissue. This can occur through transfusions, pregnancies, or previous transplants. Panel Reactive Antibodies (PRA) Class II specifically target the HLA class II molecules, which are primarily found on immune system cells. The presence of these antibodies can lead to complications in organ transplantation and certain autoimmune diseases.
Symptoms Associated with High Levels of HLA PRA Class II Antibodies
While the presence of HLA PRA Class II antibodies themselves may not directly cause symptoms, their effects can manifest in various ways, particularly in the context of organ transplantation and autoimmune diseases:
- Rejection of Transplanted Organs: Individuals with high levels of these antibodies are at a higher risk of rejecting transplanted organs. This is because the immune system recognizes the transplanted organ as foreign and attacks it.
- Autoimmune Disorders: Certain autoimmune conditions are associated with the presence of HLA antibodies. These antibodies can exacerbate symptoms of diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA).
- Difficulty in Finding Compatible Donors: For patients requiring organ transplants, high levels of HLA antibodies can make it challenging to find a compatible donor, leading to longer wait times for transplantation.
Importance of the HLA PRA Class II Quantitative Test
The HLA PRA Class II Quantitative Test offered by DNA Labs UAE is a crucial diagnostic tool for assessing the risk of organ transplant rejection and managing autoimmune diseases. By quantitatively measuring the levels of HLA PRA Class II antibodies, healthcare providers can make informed decisions regarding pre-transplant immunosuppressive therapies, donor selection, and post-transplant monitoring. Furthermore, this test can help in the diagnosis and management of autoimmune diseases by identifying the presence of specific antibodies associated with these conditions.
Cost and Accessibility of the Test
The cost of the HLA PRA Class II Quantitative Test at DNA Labs UAE is 2460 AED. This test is accessible through their state-of-the-art laboratory facilities, ensuring accurate and reliable results. For more information or to schedule a test, please visit DNA Labs UAE.
Conclusion
The presence of HLA PRA Class II antibodies is a significant factor in the success of organ transplants and the management of autoimmune diseases. The HLA PRA Class II Quantitative Test provided by DNA Labs UAE offers a comprehensive assessment of these antibodies, aiding in the effective management and treatment of patients. With the test priced at 2460 AED, it is a valuable resource for patients and healthcare providers alike in the UAE.
