Symptoms of CYBB Gene Granulomatous Disease Chronic X-Linked
Chronic Granulomatous Disease (CGD) is a rare, inherited immunodeficiency disorder that affects the body’s ability to fight off certain types of infections and inflammations. It is caused by mutations in the CYBB gene, which is located on the X chromosome, making the disease X-linked. This gene is crucial for the proper functioning of phagocytes, a type of white blood cell that plays a vital role in the immune response by engulfing and destroying bacteria and fungi.
Individuals with CGD are more susceptible to infections caused by specific bacteria and fungi. The symptoms can vary widely among affected individuals, ranging from mild to severe, and may include:
- Recurrent bacterial and fungal infections
- Granulomas, which are masses or nodules caused by inflammation, often found in the lungs, liver, skin, or lymph nodes
- Persistent diarrhea
- Skin rashes
- Failure to thrive in infancy
- Fevers
- Abdominal pain
- Pneumonia
- Weight loss
Due to the X-linked nature of the disease, males are primarily affected, while females can be carriers and may exhibit milder symptoms or none at all. Early diagnosis and treatment are crucial to manage symptoms and prevent severe infections.
Genetic Testing for CYBB Gene Granulomatous Disease
Genetic testing plays a critical role in the diagnosis of CYBB Gene Granulomatous Disease. DNA Labs UAE offers a comprehensive CYBB Gene Granulomatous Disease Chronic X-Linked Genetic Test designed to identify mutations in the CYBB gene. This test is vital for confirming the diagnosis, understanding the risk of passing the condition to future generations, and making informed decisions regarding treatment and management.
The test involves collecting a DNA sample, typically through a blood draw or cheek swab, which is then analyzed in the laboratory for the presence of mutations in the CYBB gene. The process is straightforward, with minimal discomfort to the patient.
Cost of the Genetic Test
The cost of the CYBB Gene Granulomatous Disease Chronic X-Linked Genetic Test at DNA Labs UAE is 4400 AED. This investment covers the comprehensive analysis required to accurately identify mutations in the CYBB gene, providing invaluable information for affected individuals and their families.
Understanding the genetic basis of Chronic Granulomatous Disease can significantly impact the management of the condition. With accurate diagnosis, individuals can receive targeted treatments and interventions to improve their quality of life and reduce the risk of severe infections.
For more information on the CYBB Gene Granulomatous Disease Chronic X-Linked Genetic Test and to schedule a test, please visit DNA Labs UAE.
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