Understanding Beckwith-Wiedemann Syndrome (BWS)
Beckwith-Wiedemann Syndrome (BWS) is a congenital growth disorder that leads to large body size, large organs (organomegaly), and other symptoms. It is a rare condition, affecting approximately 1 in 10,400 newborns worldwide. BWS is associated with abnormalities in the chromosomal region 11p15, where genetic changes increase the risk of developing this condition.
Symptoms of Beckwith-Wiedemann Syndrome
BWS presents a range of symptoms, which can vary significantly among individuals. Some of the most common signs include:
- Macrosomia (large body size at birth)
- Macroglossia (enlarged tongue)
- Abdominal wall defects such as omphalocele or umbilical hernia
- Ear creases or pits
- Neonatal hypoglycemia (low blood sugar levels in newborns)
- Organomegaly (enlarged organs), particularly the liver, kidneys, and pancreas
- Hemihyperplasia (one side of the body is larger than the other)
- Increased risk of developing certain types of tumors, such as Wilms tumor, hepatoblastoma, and neuroblastoma, especially in early childhood
It’s important to note that the presence and severity of these symptoms can vary. Some individuals with BWS may have mild symptoms, while others may experience more severe manifestations of the syndrome.
Genetic Testing for Beckwith-Wiedemann Syndrome
Genetic testing plays a crucial role in diagnosing Beckwith-Wiedemann Syndrome. DNA Labs UAE offers a comprehensive Chr. 11p15 Gene Beckwith-Wiedemann Syndrome Genetic Test that helps in confirming the diagnosis. This test specifically looks for abnormalities in the 11p15 region of the chromosome, which are indicative of BWS.
Why Choose DNA Labs UAE for Your Genetic Testing Needs?
Choosing DNA Labs UAE for genetic testing offers numerous benefits, including:
- State-of-the-art testing facilities
- Highly qualified and experienced geneticists and laboratory technicians
- Comprehensive genetic counseling services
- Fast and accurate test results
- Confidential handling of all genetic information
Cost of the Genetic Test
The cost of the Chr. 11p15 Gene Beckwith-Wiedemann Syndrome Genetic Test at DNA Labs UAE is 4400 AED. This cost is inclusive of the genetic test, pre-test counseling, and a detailed report of the findings. The investment in this test can provide invaluable information for families, enabling informed decisions regarding management and care for individuals with BWS.
Conclusion
Beckwith-Wiedemann Syndrome is a complex condition that requires a comprehensive approach to diagnosis and management. Genetic testing for BWS at DNA Labs UAE can provide families with the crucial information needed to understand the condition better and take proactive steps in caring for their loved ones. If you suspect that you or your child may have symptoms of BWS, consider reaching out to DNA Labs UAE for a consultation on the Chr. 11p15 Gene Beckwith-Wiedemann Syndrome Genetic Test.
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