Alpha Thalassemia is a blood disorder reducing the production of hemoglobin, the iron-containing protein in red blood cells that carries oxygen to cells throughout the body. This condition is caused by mutations in the HBA1 and HBA2 genes. Identifying the presence of these mutations is crucial for diagnosis, treatment, and family planning. DNA Labs UAE offers a comprehensive gene analysis for Alpha Thalassemia through the HBA1 – HBA2 Test, priced at 4800 AED.
Symptoms of Alpha Thalassemia
Alpha Thalassemia is characterized by a wide range of symptoms, depending on the severity of the condition. It is divided into two main types: Alpha Thalassemia Minor and Alpha Thalassemia Major (also known as Hemoglobin H disease and Hydrops Fetalis, respectively). The symptoms can vary significantly from mild to life-threatening.
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Mild Alpha Thalassemia (Silent Carrier or Alpha Thalassemia Minor): Individuals often exhibit no symptoms and may not know they carry the gene mutations. It is usually detected through routine blood tests.
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Hemoglobin H Disease: Symptoms may include chronic anemia, fatigue, pale skin, jaundice, and an enlarged spleen. These symptoms are more pronounced and can affect the quality of life.
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Hydrops Fetalis: This is the most severe form of Alpha Thalassemia and is usually fatal before or shortly after birth. It is characterized by an inability of the fetus to produce functional hemoglobin, leading to severe anemia and heart failure.
Importance of the HBA1 – HBA2 Test
The HBA1 – HBA2 Test is a genetic analysis that identifies mutations in the HBA1 and HBA2 genes, responsible for Alpha Thalassemia. This test is crucial for:
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Detecting carriers of the Alpha Thalassemia trait, especially in regions where the condition is prevalent or if there is a family history of the disease.
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Providing a definitive diagnosis for individuals exhibiting symptoms of Alpha Thalassemia.
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Informing couples of their risk of having a child with Alpha Thalassemia, facilitating informed family planning decisions.
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Guiding treatment plans for those diagnosed with the condition, particularly in determining the necessity and frequency of blood transfusions or iron chelation therapy.
Test Cost and Procedure
The HBA1 – HBA2 Test offered by DNA Labs UAE is priced at 4800 AED. The test involves a simple blood draw from the arm, which is then analyzed in the laboratory for genetic mutations. The procedure is straightforward and has minimal risks, similar to any routine blood test. Results are typically available within a few weeks and provide valuable information for managing Alpha Thalassemia.
Conclusion
Alpha Thalassemia is a genetic condition that can have significant health implications. Early detection through the HBA1 – HBA2 Test is essential for managing the condition and planning for a healthy future. DNA Labs UAE is committed to providing accurate and comprehensive genetic testing services to help individuals and families understand their genetic health. For more information on the Alpha Thalassemia Gene Analysis HBA1 – HBA2 Test, visit DNA Labs UAE.
