Oncology Diseases

The CALR gene, known scientifically as Calreticulin, plays a significant role in the human body, impacting various physiological processes, including calcium homeostasis and the proper functioning of the immune system. Mutations in this gene have been closely associated with certain types of blood disorders, particularly Myeloproliferative Neoplasms (MPNs). MPNs are a group of disorders characterized […]

In the realm of genetic diagnostics and personalized medicine, understanding the intricate relationship between our genes and health conditions is paramount. Among the myriad of genetic disorders, carcinoid tumors associated with the SDHD gene represent a significant area of concern due to their potential impact on the intestinal tract. DNA Labs UAE, a leading genetic […]

The PRKAR1A gene plays a pivotal role in the normal functioning of the body’s cells, influencing how they grow, divide, and communicate with one another. Mutations in this gene are associated with Carney Complex Type 1, a rare genetic disorder that affects multiple systems in the body and predisposes individuals to various benign and malignant […]

Understanding the CDC20 Gene Cell Cycle Disorder and the Importance of CDC20 Related Genetic Testing The CDC20 gene plays a critical role in the cell cycle, specifically in the activation of the anaphase-promoting complex/cyclosome (APC/C), which is essential for the transition from metaphase to anaphase during cell division. Mutations or dysregulation in the CDC20 gene […]

Beckwith-Wiedemann Syndrome (BWS) is a complex genetic disorder that affects many parts of the body. It is characterized by a wide range of symptoms and features, which can vary significantly from one individual to another. The syndrome is primarily known for causing overgrowth and an increased risk of developing childhood cancer. The CDKN1C gene plays […]

Symptoms of NRAS Gene Colorectal Cancer Hereditary Genetic Test Colorectal cancer is a significant health concern globally, affecting millions of individuals each year. It is the development of cancer from the colon or rectum, parts of the large intestine. Among the various factors that contribute to the onset of colorectal cancer, genetic mutations play a […]

Understanding Beckwith-Wiedemann Syndrome (BWS) Beckwith-Wiedemann Syndrome (BWS) is a congenital growth disorder that leads to large body size, large organs (organomegaly), and other symptoms. It is a rare condition, affecting approximately 1 in 10,400 newborns worldwide. BWS is associated with abnormalities in the chromosomal region 11p15, where genetic changes increase the risk of developing this […]

Colorectal cancer stands as one of the leading causes of cancer-related deaths worldwide. However, a significant proportion of these cases have a hereditary component, notably the Hereditary Nonpolyposis Colorectal Cancer (HNPCC) or Lynch Syndrome. Central to this condition is the mutation of the MSH2 gene, a critical player in DNA repair mechanisms. Understanding the symptoms […]

Beckwith-Wiedemann Syndrome (BWS) is a genetic disorder that affects many parts of the body and is characterized by overgrowth. It is a condition present from birth and varies greatly in how it affects individuals. One of the genes associated with this syndrome is the H19 gene, and testing for abnormalities in this gene can help […]

Understanding the implications of genetic mutations and their effects on our health is a pivotal aspect of modern medicine. One such condition that has garnered attention is Hereditary Nonpolyposis Colorectal Cancer (HNPCC), also known as Lynch Syndrome. This condition is significantly associated with mutations in the MLH1 gene, among others. In this context, DNA Labs […]