Symptoms of ZFYVE26 Gene SPG15 Genetic Test Hereditary spastic paraplegia type 15 (SPG15), also known as ZFYVE26-related spastic paraplegia, is a complex form of hereditary spastic paraplegia. It is characterized by progressive weakness and spasticity of the legs, often in combination with other neurological and systemic manifestations. This condition is caused by mutations in the […]











